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Longitudinal uric acid has nonlinear association with kidney failure and mortality in chronic kidney disease
We investigated the shape of the relationship between longitudinal uric acid (UA) and the hazard of kidney failure and death in chronic kidney...
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Urinary vanin-1, tubular injury, and graft failure in kidney transplant recipients
We investigated whether urinary vascular non-inflammatory molecule-1 (vanin-1), a promising early-onset tubular injury marker, correlates with other...
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People with genetic kidney diseases on kidney replacement therapy have different clinical outcomes compared to people with other kidney diseases
Despite increasing awareness of genetic kidney disease prevalence, there is limited population-level information about long term outcomes of people...
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Sex disparities in mortality among patients with kidney failure receiving dialysis
Females are known to have a better survival rate than males in the general population, but previous studies have shown that this superior survival is...
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Polyphenol-rich açaí seed extract exhibits reno-protective and anti-fibrotic activities in renal tubular cells and mice with kidney failure
The main goal of this study was to evaluate the reno-protective effects of a phenolic-rich Açaí seed extract (ASE) in mice with kidney failure....
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The association between changes in echocardiography and risk of heart failure hospitalizations and death in adults with chronic kidney disease
Adults with chronic kidney disease (CKD) are at increased risk for develo** heart failure (HF). However, longitudinal cardiac remodeling in CKD has...
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Association between iron status markers and kidney outcome in patients with chronic kidney disease
Several studies conducted in patients with various stages of chronic kidney disease (CKD) have investigated the association of iron status markers,...
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Impact of iron status on kidney outcomes in kidney transplant recipients
Iron plays an important role in hemodynamics and the immunity, independent of anemia. Since dynamic changes occur in iron storage after kidney...
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The significance of chronic kidney disease, heart failure and cardiovascular disease for mortality in type 1 diabetes: nationwide observational study
People with type 1 diabetes have a substantially increased risk of premature death. This nationwide, register-based cohort study evaluated the...
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Human peritoneal tight junction, transporter and channel expression in health and kidney failure, and associated solute transport
Next to the skin, the peritoneum is the largest human organ, essentially involved in abdominal health and disease states, but information on...
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Comparison of long-term outcomes in simultaneous pancreas-kidney transplant versus simultaneous deceased donor pancreas and living donor kidney transplant
Simultaneous deceased donor pancreas and living donor kidney transplant (SPLK) has certain advantages over conventional simultaneous pancreas-kidney...
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Longitudinal genome-wide DNA methylation changes in response to kidney failure replacement therapy
Chronic kidney disease (CKD) is an emerging public health priority associated with high mortality rates and demanding treatment regimens, including...
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A Nuphar lutea plant active ingredient, 6,6′-dihydroxythiobinupharidine, ameliorates kidney damage and inflammation in a mouse model of chronic kidney disease
Chronic Kidney Disease (CKD) associated complications are associated with increased inflammation through the innate immune response, which can be...
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Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease
The kidney has large regenerative capacity, but this is compromised when kidney damage is excessive and renal tubular epithelial cells (TECs) undergo...
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Axillary mechanical circulatory support improves renal function prior to heart transplantation in patients with chronic kidney disease
Impaired kidney function is often associated with acute decompensation of chronic heart failure and portends a poor prognosis. Unfortunately, current...
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Association between urinary uric acid excretion and kidney outcome in patients with CKD
Inhibiting tubular urate reabsorption may protect the kidney from urate-induced tubular injury. However, this approach may promote intratubular uric...
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Impact of acute kidney injury and renal recovery status in deceased donor to kidney transplant outcome: results from the Thai national transplant registry
The influence of acute kidney injury (AKI) and renal recovery in deceased donor (DD) on long-term kidney transplant (KT) outcome has not previously...
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Choroidal and retinal thinning in chronic kidney disease independently associate with eGFR decline and are modifiable with treatment
In patients with chronic kidney disease (CKD), there is an unmet need for novel biomarkers that reliably track kidney injury, demonstrate...
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DNA methylation markers for kidney function and progression of diabetic kidney disease
Epigenetic markers are potential biomarkers for diabetes and related complications. Using a prospective cohort from the Hong Kong Diabetes Register,...
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Associations of air pollutant concentrations with longitudinal kidney function changes in patients with chronic kidney disease
This longitudinal cohort study investigated the associations of air pollutant exposures, including CO, NO, NO 2 , NO x , O 3 , PM 10 , PM 2.5 , and SO 2 , with...
