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Showing 1-20 of 884 results
  1. Combination of treatments with transoral endoscopic thyroidectomy vestibular approach (TOETVA) for Graves’ disease

    Although the success rates of non-surgical treatments for Graves’ disease such as antithyroid medication and radioiodine ablation were good, there...

    Yi-Ju Wu, Yen-Hsiang Chang, ... Yi Ting Yang in Scientific Reports
    Article Open access 16 February 2023
  2. The influence of thionamides on intra-thyroidal uptake of 131I during radioiodine-131 treatment of Graves’ disease

    Graves’ disease is one of the most common causes of hyperthyroidism. Guideline recommendations advocate the intake of thionamides for at least...

    Christian Happel, Benjamin Bockisch, ... Daniel Groener in Scientific Reports
    Article Open access 01 December 2023
  3. Comprehensive immunophenotypic analysis reveals the pathological involvement of Th17 cells in Graves' disease

    Graves' disease (GD) is an organ-specific autoimmune disease, but there are a few studies that have evaluated how immunophenotypes are related to...

    Keiichi Torimoto, Yosuke Okada, ... Yoshiya Tanaka in Scientific Reports
    Article Open access 07 October 2022
  4. Biological and substitute parents in Beaker period adult–child graves

    Joint inhumations of adults and children are an intriguing aspect of the shift from collective to single burial rites in third millennium BC Western...

    Nicoletta Zedda, Katie Meheux, ... Maxime Brami in Scientific Reports
    Article Open access 31 October 2023
  5. EZH2 as a major histone methyltransferase in PDGF-BB-activated orbital fibroblast in the pathogenesis of Graves’ ophthalmopathy

    Graves’ ophthalmopathy (GO) is an extra-thyroidal complication of Graves’ disease which can lead to vision loss in severe cases. Currently,...

    Sopita Visamol, Tanapat Palaga, ... Sita Virakul in Scientific Reports
    Article Open access 04 April 2024
  6. Possible interplay between estrogen and the BAFF may modify thyroid activity in Graves’ disease

    A link between sex hormones and B-cell activating factor (BAFF), a crucial immunoregulator of autoimmune thyroid disease (AITD), may exist. The study...

    Chao-Wen Cheng, Wen-Fang Fang, ... Jiunn-Diann Lin in Scientific Reports
    Article Open access 01 November 2021
  7. Expansion of inflammatory monocytes in periphery and infiltrated into thyroid tissue in Graves’ disease

    Monocytes are important mediators of immune system and are reported to be altered in autoimmune disorders. Little is known about the pathological...

    **nxin Chen, Yanqiu Wang, ... Shu Wang in Scientific Reports
    Article Open access 29 June 2021
  8. Neural network-based method for diagnosis and severity assessment of Graves’ orbitopathy using orbital computed tomography

    Computed tomography (CT) has been widely used to diagnose Graves’ orbitopathy, and the utility is gradually increasing. To develop a neural network...

    Jaesung Lee, Wangduk Seo, ... Jeong Kyu Lee in Scientific Reports
    Article Open access 15 July 2022
  9. Automated detection of enlarged extraocular muscle in Graves’ ophthalmopathy with computed tomography and deep neural network

    This study aimed to develop a diagnostic software system to evaluate the enlarged extraocular muscles (EEM) in patients with Graves’ ophthalmopathy...

    Kaori Hanai, Hitoshi Tabuchi, ... Masato Hashimoto in Scientific Reports
    Article Open access 26 September 2022
  10. Risk of incident autoimmune diseases in patients with newly diagnosed psoriatic disease: a nationwide population-based study

    There are limited large population-based cohort studies on the risk of incident autoimmune diseases among patients with newly diagnosed psoriatic...

    Joon Min Jung, Ye-Jee Kim, ... Sung Eun Chang in Scientific Reports
    Article Open access 05 October 2023
  11. Effects of various extraocular muscle enlargement patterns on muscle diameter index in graves ophthalmopathy patients: a retrospective cohort study

    Graves ophthalmopathy (GO) patients often undergo retrobulbar injection of glucocorticoids (GCs) as a common therapeutic approach. This study aimed...

    Junjie Yang, ** Chen, ... Fagang Jiang in Scientific Reports
    Article Open access 07 October 2023
  12. Vasoactive intestinal peptide axis is dysfunctional in patients with Graves’ disease

    Vasoactive intestinal peptide (VIP) is a neuropeptide with potent immunoregulatory properties. Reduced serum VIP levels and alterations in VIP...

    M. Carrión, A. M. Ramos-Leví, ... Mónica Marazuela in Scientific Reports
    Article Open access 03 August 2020
  13. Vitamin D supplementation does not prevent the recurrence of Graves’ disease

    Recent literature has reported a higher prevalence of vitamin D deficiency among people with Graves’ disease. No study has examined the effect of...

    Yoon Young Cho, Yun Jae Chung in Scientific Reports
    Article Open access 08 January 2020
  14. Comprehensive analysis of chemokine gene polymorphisms in Korean children with autoimmune thyroid disease

    Chemokines are chemotactic cytokines that can cause directed migration of leukocytes. The aim of this study was to examine differences in single...

    Chungwoo Shin, In-Cheol Baek, ... Byung-Kyu Suh in Scientific Reports
    Article Open access 20 September 2023
  15. Phenome of coeliac disease vs. inflammatory bowel disease

    Coeliac disease (CeD) is characterized by gliadin-induced intestinal inflammation appearing in genetically susceptible individuals, such as HLA-DQ2.5...

    Moritz Kleinjans, Carolin V. Schneider, ... Pavel Strnad in Scientific Reports
    Article Open access 26 August 2022
  16. Morphometric and volumetric analysis of lacrimal glands in patients with thyroid eye disease

    Assessment of morphometric and volumetric changes in lacrimal glands in thyroid eye disease, its clinical manifestations in relation of disease...

    Ana Starčević, Zoran Radojičić, ... Igor Djoric in Scientific Reports
    Article Open access 28 September 2023
  17. Real-time quantitation of thyroidal radioiodine uptake in thyroid disease with monitoring by a collar detection device

    Radioactive iodine (RAI) is safe and effective in most patients with hyperthyroidism but not all individuals are cured by the first dose, and most...

    Prasanna Santhanam, Lilja Solnes, ... Paul W. Ladenson in Scientific Reports
    Article Open access 16 September 2021
  18. Purine metabolism-related genes and immunization in thyroid eye disease were validated using bioinformatics and machine learning

    Thyroid eye disease (TED), an autoimmune inflammatory disorder affecting the orbit, exhibits a range of clinical manifestations. While the disease...

    Zixuan Wu, Yuan Gao, ... **aolei Yao in Scientific Reports
    Article Open access 26 October 2023
  19. Start codon variant in LAG3 is associated with decreased LAG-3 expression and increased risk of autoimmune thyroid disease

    Autoimmune thyroid disease (AITD) is a common autoimmune disease. In a GWAS meta-analysis of 110,945 cases and 1,084,290 controls, 290 sequence...

    Saedis Saevarsdottir, Kristbjörg Bjarnadottir, ... Kari Stefansson in Nature Communications
    Article Open access 09 July 2024
  20. Diagnoses of obstetric and postpartum thyroid disease: a Danish validation study

    Different diagnoses of thyroid disease are available in the 10th International Classification of Diseases (ICD-10), but the validity of diagnoses...

    Anne Myrup Houmøller, Katrine Gerlif, ... Stine Linding Andersen in Scientific Reports
    Article Open access 16 April 2024
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