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Combination of treatments with transoral endoscopic thyroidectomy vestibular approach (TOETVA) for Graves’ disease
Although the success rates of non-surgical treatments for Graves’ disease such as antithyroid medication and radioiodine ablation were good, there...
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The influence of thionamides on intra-thyroidal uptake of 131I during radioiodine-131 treatment of Graves’ disease
Graves’ disease is one of the most common causes of hyperthyroidism. Guideline recommendations advocate the intake of thionamides for at least...
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Comprehensive immunophenotypic analysis reveals the pathological involvement of Th17 cells in Graves' disease
Graves' disease (GD) is an organ-specific autoimmune disease, but there are a few studies that have evaluated how immunophenotypes are related to...
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Biological and substitute parents in Beaker period adult–child graves
Joint inhumations of adults and children are an intriguing aspect of the shift from collective to single burial rites in third millennium BC Western...
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EZH2 as a major histone methyltransferase in PDGF-BB-activated orbital fibroblast in the pathogenesis of Graves’ ophthalmopathy
Graves’ ophthalmopathy (GO) is an extra-thyroidal complication of Graves’ disease which can lead to vision loss in severe cases. Currently,...
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Possible interplay between estrogen and the BAFF may modify thyroid activity in Graves’ disease
A link between sex hormones and B-cell activating factor (BAFF), a crucial immunoregulator of autoimmune thyroid disease (AITD), may exist. The study...
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Expansion of inflammatory monocytes in periphery and infiltrated into thyroid tissue in Graves’ disease
Monocytes are important mediators of immune system and are reported to be altered in autoimmune disorders. Little is known about the pathological...
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Neural network-based method for diagnosis and severity assessment of Graves’ orbitopathy using orbital computed tomography
Computed tomography (CT) has been widely used to diagnose Graves’ orbitopathy, and the utility is gradually increasing. To develop a neural network...
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Automated detection of enlarged extraocular muscle in Graves’ ophthalmopathy with computed tomography and deep neural network
This study aimed to develop a diagnostic software system to evaluate the enlarged extraocular muscles (EEM) in patients with Graves’ ophthalmopathy...
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Risk of incident autoimmune diseases in patients with newly diagnosed psoriatic disease: a nationwide population-based study
There are limited large population-based cohort studies on the risk of incident autoimmune diseases among patients with newly diagnosed psoriatic...
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Effects of various extraocular muscle enlargement patterns on muscle diameter index in graves ophthalmopathy patients: a retrospective cohort study
Graves ophthalmopathy (GO) patients often undergo retrobulbar injection of glucocorticoids (GCs) as a common therapeutic approach. This study aimed...
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Vasoactive intestinal peptide axis is dysfunctional in patients with Graves’ disease
Vasoactive intestinal peptide (VIP) is a neuropeptide with potent immunoregulatory properties. Reduced serum VIP levels and alterations in VIP...
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Vitamin D supplementation does not prevent the recurrence of Graves’ disease
Recent literature has reported a higher prevalence of vitamin D deficiency among people with Graves’ disease. No study has examined the effect of...
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Comprehensive analysis of chemokine gene polymorphisms in Korean children with autoimmune thyroid disease
Chemokines are chemotactic cytokines that can cause directed migration of leukocytes. The aim of this study was to examine differences in single...
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Phenome of coeliac disease vs. inflammatory bowel disease
Coeliac disease (CeD) is characterized by gliadin-induced intestinal inflammation appearing in genetically susceptible individuals, such as HLA-DQ2.5...
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Morphometric and volumetric analysis of lacrimal glands in patients with thyroid eye disease
Assessment of morphometric and volumetric changes in lacrimal glands in thyroid eye disease, its clinical manifestations in relation of disease...
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Real-time quantitation of thyroidal radioiodine uptake in thyroid disease with monitoring by a collar detection device
Radioactive iodine (RAI) is safe and effective in most patients with hyperthyroidism but not all individuals are cured by the first dose, and most...
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Purine metabolism-related genes and immunization in thyroid eye disease were validated using bioinformatics and machine learning
Thyroid eye disease (TED), an autoimmune inflammatory disorder affecting the orbit, exhibits a range of clinical manifestations. While the disease...
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Start codon variant in LAG3 is associated with decreased LAG-3 expression and increased risk of autoimmune thyroid disease
Autoimmune thyroid disease (AITD) is a common autoimmune disease. In a GWAS meta-analysis of 110,945 cases and 1,084,290 controls, 290 sequence...
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Diagnoses of obstetric and postpartum thyroid disease: a Danish validation study
Different diagnoses of thyroid disease are available in the 10th International Classification of Diseases (ICD-10), but the validity of diagnoses...