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The effect of decellularization protocols on characterizations of thermoresponsive and light-curable corneal extracellular matrix hydrogels
To compare the effects of two decellularization protocols on the characteristics of fabricated COrnea Matrix (COMatrix) hydrogels. Porcine corneas...
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Interindividual heterogeneity affects the outcome of human cardiac tissue decellularization
The extracellular matrix (ECM) of engineered human cardiac tissues corresponds to simplistic biomaterials that allow tissue assembly, or animal...
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Supercritical carbon dioxide decellularization of plant material to generate 3D biocompatible scaffolds
The use of plant-based biomaterials for tissue engineering has recently generated interest as plant decellularization produces biocompatible...
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Removal of an abluminal lining improves decellularization of human umbilical arteries
The decellularization of long segments of tubular tissues such as blood vessels may be improved by perfusing decellularization solution into their...
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Development and qualification of clinical grade decellularized and cryopreserved human esophagi
Tissue engineering is a promising alternative to current full thickness circumferential esophageal replacement methods. The aim of our study was to...
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The impact of decellularization methods on extracellular matrix derived hydrogels
Tissue-derived decellularized biomaterials are ideal for tissue engineering applications as they mimic the biochemical composition of the native...
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Pressurized carbon dioxide as a potential tool for decellularization of pulmonary arteries for transplant purposes
Vascular bio-scaffolds produced from decellularized tissue offer a promising material for treatment of several types of cardiovascular diseases....
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Capturing effects of blood flow on the transplanted decellularized nephron with intravital microscopy
Organ decellularization creates cell-free, collagen-based extracellular matrices that can be used as scaffolds for tissue engineering applications....
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Bioengineering of vascularized porcine flaps using perfusion-recellularization
Large volume soft tissue defects greatly impact patient quality of life and function while suitable repair options remain a challenge in...
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Complete Human Penile Scaffold for Composite Tissue Engineering: Organ Decellularization and Characterization
Reconstruction for total penile defects presents unique challenges due to its anatomical and functional complexity. Standard methods suffer from high...
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A non-linear mathematical model using optical sensor to predict heart decellularization efficacy
One of the main problems of the decellularization technique is the subjectivity of the final evaluation of its efficacy in individual organs. This...
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Macromolecular crowding regulates matrix composition and gene expression in human gingival fibroblast cultures
Standard cell cultures are performed in aqueous media with a low macromolecule concentration compared to tissue microenvironment. In macromolecular...
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Recellularized lymph node scaffolds with human adipose-derived stem cells enhance lymph node regeneration to improve lymphedema
To overcome the limitations of lymphedema treatment, human adipose-derived stem cells (hADSCs) were injected into decellularized lymph nodes to...
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A novel approach for the endothelialization of xenogeneic decellularized vascular tissues by human cells utilizing surface modification and dynamic culture
Decellularized xenogeneic vascular grafts can be used in revascularization surgeries. We have developed decellularization methods using high...
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Intravital microscopy datasets examining key nephron segments of transplanted decellularized kidneys
This study contains intravital microscopy (IVM) data examining the microarchitecture of acellular kidney scaffolds. Acellular scaffolds are cell-free...
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Generation of vascular chimerism within donor organs
Whole organ perfusion decellularization has been proposed as a promising method to generate non-immunogenic organs from allogeneic and xenogeneic...
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Evaluation of ethylene oxide, gamma radiation, dry heat and autoclave sterilization processes on extracellular matrix of biomaterial dental scaffolds
Scaffolds used to receive stem cells are a promising perspective of tissue regeneration research, and one of the most effective solutions to rebuild...
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Photocrosslinkable liver extracellular matrix hydrogels for the generation of 3D liver microenvironment models
Liver extracellular matrix (ECM)-based hydrogels have gained considerable interest as biomimetic 3D cell culture environments to investigate the...
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A decellularized human corneal scaffold for anterior corneal surface reconstruction
Allogenic transplants of the cornea are prone to rejection, especially in repetitive transplantation and in scarred or highly vascularized recipient...
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Spatially resolved proteomic map shows that extracellular matrix regulates epidermal growth
Human skin comprises stratified squamous epithelium and dermis with various stromal cells and the extracellular matrix (ECM). The basement membrane...
