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Structural insights into functional properties of the oxidized form of cytochrome c oxidase
Cytochrome c oxidase (C c O) is an essential enzyme in mitochondrial and bacterial respiration. It catalyzes the four-electron reduction of molecular...
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A highly sensitive uric acid electrochemical biosensor based on a nano-cube cuprous oxide/ferrocene/uricase modified glassy carbon electrode
A uric acid (UA) electrochemical biosensor was constructed using ferrocene (Fc) decorated cuprous oxide (Cu 2 O) enhanced electro-active...
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Crystal structures of multicopper oxidase CueO G304K mutant: structural basis of the increased laccase activity
The multicopper oxidase CueO is involved in copper homeostasis and copper (Cu) tolerance in Escherichia coli . The laccase activity of CueO G304K...
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Signal processing and generation of bioactive nitric oxide in a model prototissue
The design and construction of synthetic prototissues from integrated assemblies of artificial protocells is an important challenge for synthetic...
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Alkyne-tagged SERS nanoprobe for understanding Cu+ and Cu2+ conversion in cuproptosis processes
Simultaneously quantifying mitochondrial Cu + and Cu 2+ levels is crucial for evaluating the molecular mechanisms of copper accumulation-involved...
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Ultrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases
Oxidative stress is associated with many acute and chronic inflammatory diseases, yet limited treatment is currently available clinically. The...
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Silicon nitride: a potent solid-state bioceramic inactivator of ssRNA viruses
Surface inactivation of human microbial pathogens has a long history. The Smith Papyrus (2600 ~ 2200 B.C.) described the use of copper surfaces to...
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The Terminal Oxidase Cytochrome bd Promotes Sulfide-resistant Bacterial Respiration and Growth
Hydrogen sulfide (H 2 S) impairs mitochondrial respiration by potently inhibiting the heme-copper cytochrome c oxidase. Since many prokaryotes,...
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Changes in intracellular copper concentration and copper-regulating gene expression after PC12 differentiation into neurons
It is suspected that some neurodegenerative diseases are a result of the disturbance of copper (Cu) homeostasis, although it remains unclear whether...
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Copper content of staple seeds and grains grown in Kanam local government area, Nigeria
Copper is a trace mineral that plays an important role in human metabolism, largely because it allows many critical enzymes to function properly....
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Progress of marine biofouling and antifouling technologies
Adhesion of marine fouling organisms on artificial surfaces such as ship hulls causes many problems, including extra energy consumption, high...
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Protein-folding location can regulate manganese-binding versus copper- or zinc-binding
Metals are needed by at least one-quarter of all proteins
1 ,2 . Although metallochaperones3 ,4 ,5 ,6 ,7 ,8 insert the correct metal into some proteins, they...
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Carcinogenesis of asbestos switched on by inducing cross-linkage between DNA complementary pair bases
Since the beginning of the 1980s, Dai Qianhuan predicted based upon his di-region theory that the carcinogenesis switched on by the so-called...
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Metal-Complex-Catalyzed Cleavage of Biopolymers
Oxygen radical species such as the superoxide (O 2 - ), hydroxyl (· OH), and hydroperoxyl (· OOH) radicals...
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Milk and Milk Products
Milk is the normal secretion of the mammary glands for the feeding of the young of mammals. In the United States, the primary milk in commerce is...
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Metal-binding substances
Heavy metals, in traces, are essential for all forms of life. They are taken up by the living cell as cations, and their uptake is strictly regulated...
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Metal ions in biological systems
The study of the biological role of metal ions has a long history in medicine, in pharmacology and in toxicology but it is only recently that the...
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Browning Reactions
There are two important forms of browning, enzymatic and nonenzymatic. This color development is usually undesirable, but with a knowledge of the...
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Lipid Oxidation
Oxidation of lipids involves complex chemical reactions between lipids and oxygen mediated by a variety of catalysts. Active oxygen species such as...
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Carbohydrates
Carbohydrates are found throughout the world and, of all the biological substances in the plant kingdom other than water, they are present in the...