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A plasmid network from the gut microbiome of semi-isolated human groups reveals unique and shared metabolic and virulence traits
The plasmids in gut microbiomes have the potential to contribute to the microbiome community, as well as human health and physiology. Nevertheless,...
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Direct detection of iro B, stn and hil A virulence genes in Salmonella enterica serovar typhimurium from non-ripened cheese
BackgroundMicroorganisms' survival is based on the importance of growth factors found in the microbial environment, as well as their overwhelming...
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The cell envelope of Staphylococcus aureus selectively controls the sorting of virulence factors
Staphylococcus aureus bi-component pore-forming leukocidins are secreted toxins that directly target and lyse immune cells. Intriguingly, one of the...
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Genome analysis provides insight into hyper-virulence of Streptococcus suis LSM178, a human strain with a novel sequence type 1005
Streptococcus suis has been well-recognized as a zoonotic pathogen worldwide, and the diversity and unpredictable adaptive potential of sporadic...
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Promiscuity of response regulators for thioredoxin steers bacterial virulence
The exquisite specificity between a sensor kinase and its cognate response regulator ensures faithful partner selectivity within two-component pairs...
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The fliR gene contributes to the virulence of S. marcescens in a Drosophila intestinal infection model
Serratia marcescens is an opportunistic bacterium that infects a wide range of hosts including humans. It is a potent pathogen in a septic injury...
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A joinpoint regression model to determine COVID-19 virulence due to vaccination programme in India: a longitudinal analysis from 2020 to 2022
BackgroundIn late 2019, coronavirus disease, an acute respiratory illness caused by the novel coronavirus (SARS-CoV-2), was designated COVID-19 and...
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Delineating virulence of Vibrio campbellii: a predominant luminescent bacterial pathogen in Indian shrimp hatcheries
Luminescent vibriosis is a major bacterial disease in shrimp hatcheries and causes up to 100% mortality in larval stages of penaeid shrimps. We...
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Structure of the transcription open complex of distinct σI factors
Bacterial σ I factors of the σ 70 -family are widespread in Bacilli and Clostridia and are involved in the heat shock response, iron metabolism,...
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Full pathogen characterisation: species identification including the detection of virulence factors and antibiotic resistance genes via multiplex DNA-assays
Antibiotic resistances progressively cause treatment failures, and their spreading dynamics reached an alarming level. Some strains have already been...
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Shared antibiotic resistance and virulence genes in Staphylococcus aureus from diverse animal hosts
The emergence of methicillin-resistant Staphylococcus aureus (MRSA) poses an important threat in human and animal health. In this study, we ask...
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Shotgun-metagenomics based prediction of antibiotic resistance and virulence determinants in Staphylococcus aureus from periprosthetic tissue on blood culture bottles
Shotgun-metagenomics may give valuable clinical information beyond the detection of potential pathogen(s). Identification of antimicrobial resistance...
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Environmental factors sha** the gut microbiome in a Dutch population
The gut microbiome is associated with diverse diseases
1 –3 , but a universal signature of a healthy or unhealthy microbiome has not been identified,...
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Indole decreases the virulence of the bivalve model pathogens Vibrio tasmaniensis LGP32 and Vibrio crassostreae J2-9
Indole signaling plays an important role in bacterial pathogenesis. In this study, the impact of indole on biofilm formation, swimming and swarming...
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Structure of the master regulator Rns reveals an inhibitor of enterotoxigenic Escherichia coli virulence regulons
Enteric infections caused by the gram-negative bacteria enterotoxigenic Escherichia coli (ETEC), Vibrio cholerae , Shigella flexneri , and Salmonella...
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Genetic and virulence characteristics of a Raoultella planticola isolate resistant to carbapenem and tigecycline
Raoultella planticola is an emerging pathogen causing several infections in humans, and its roles in the propagation of antibiotic resistance genes...
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Targeting of Uropathogenic Escherichia coli papG gene using CRISPR-dot nanocomplex reduced virulence of UPEC
Urinary tract infections (UTI) are the most common infectious diseases in the world. It is becoming increasingly tough to treat because of emergence...
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Effect of volatile compounds produced by endophytic bacteria on virulence traits of grapevine crown gall pathogen, Agrobacterium tumefaciens
The volatile organic compounds (VOCs) produced by endophytic bacteria have a significant role in the control of phytopathogens. In this research, the...
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Spontaneous mutations in hlyD and tuf genes result in resistance of Dickeya solani IPO 2222 to phage ϕD5 but cause decreased bacterial fitness and virulence in planta
Lytic bacteriophages able to infect and kill Dickeya spp. can be readily isolated from virtually all Dickeya spp. containing environments, yet little...
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Complete genome sequence of fish-pathogenic Aeromonas hydrophila HX-3 and a comparative analysis: insights into virulence factors and quorum sensing
The gram-negative, aerobic, rod-shaped bacterium Aeromonas hydrophila , the causative agent of motile aeromonad septicaemia, has attracted increasing...
