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DNA-based assessment of root lesion nematode infections in cereal roots
Root lesion nematodes (RLN) of the genus Pratylenchus are causing significant damage in cereal production worldwide. Due to climate change and...
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Silica nanoparticles-induced cytotoxicity and genotoxicity in A549 cell lines
Among the myriad of nanoparticles, silica nanoparticles (SiO 2 NPs) have gained significant attention since they are extensively produced and used...
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Evaluation of a saliva molecular point of care for the detection of SARS-CoV-2 in ambulatory care
Rapid identification of SARS-CoV-2-infected individuals is a cornerstone for the control of virus spread. The sensitivity of SARS-CoV-2 RNA detection...
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Expanding diversity of bunyaviruses identified in mosquitoes
Mosquitoes interact with various organisms in the environment, and female mosquitoes in particular serve as vectors that directly transmit a number...
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Analysis of the impact of DGAT1 p.M435L and p.K232A variants on pre-mRNA splicing in a full-length gene assay
DGAT1 is playing a major role in fat metabolism and triacylglyceride synthesis. Only two DGAT1 loss-of-function variants altering milk production...
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Commercially available SARS-CoV-2 RT-qPCR diagnostic tests need obligatory internal validation
Although infection with severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) does not appear to be as serious a threat to public health as it...
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Evaluating the performance characteristics of five lateral flow assays for the detection of the SARS-CoV-2 nucleocapsid antigen
In response to the COVID-19 pandemic, lateral flow assays (LFAs) for the detection of SARS-CoV-2 antigen have been proposed as a complementary option...
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Comparison of RT-dPCR and RT-qPCR and the effects of freeze–thaw cycle and glycine release buffer for wastewater SARS-CoV-2 analysis
Public health efforts to control the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic rely on accurate information on the spread...
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KLF15 suppresses tumor growth and metastasis in Triple-Negative Breast Cancer by downregulating CCL2 and CCL7
Kruppel like factor 15 (KLF15), a transcriptional factor belonging to the Kruppel-like factor (KLF) family of genes, has recently been reported as a...
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Simultaneous monitoring of eight human respiratory viruses including SARS-CoV-2 using liquid chromatography-tandem mass spectrometry
Diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection has primarily been achieved using reverse transcriptase...
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Human viral nucleic acids concentrations in wastewater solids from Central and Coastal California USA
We measured concentrations of SARS-CoV-2, influenza A and B virus, respiratory syncytial virus (RSV), mpox virus, human metapneumovirus, norovirus...
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Development of an optimized colorimetric RT-LAMP for SARS-CoV-2 assay with enhanced procedure controls for remote diagnostics
The coronavirus pandemic accentuated the need for molecular diagnostic tests. A technique highly used to this end is the Polymerase Chain Reaction...
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A semi-automated, isolation-free, high-throughput SARS-CoV-2 reverse transcriptase (RT) loop-mediated isothermal amplification (LAMP) test
Shortages of reverse transcriptase (RT)-polymerase chain reaction (PCR) reagents and related equipment during the COVID-19 pandemic have demonstrated...
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Occurrence and characterization of viruses infecting Amorphophallus in Yunnan, China
Viral diseases are becoming an important problem in Amorphophallus production due to the propagation of seed corms and their trade across regions. In...
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The surface modification of the silica-coated magnetic nanoparticles and their application in molecular diagnostics of virus infection
The study presents a series of examples of magnetic nanoparticle systems designed for the diagnosis of viral diseases. In this interdisciplinary...
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Association of polymorphisms in TGFB1, XRCC1, XRCC3 genes and CD8 T-lymphocyte apoptosis with adverse effect of radiotherapy for prostate cancer
The genetic background of each person might affect the severity of radiotherapy (RT)-induced normal tissue toxicity. The aim of study was to evaluate...
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FISH improves risk stratification in acute leukemia by identifying KMT2A abnormal copy number and rearrangements
Most cases of acute leukemia (AL) with KMT2A rearrangement ( KMT2A -r) have a dismal prognosis. Detection of this aberration in Chinese adult patients...
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The potential key genes and pathways associated with Wilms tumor in quest of proper candidates for diagnostic and therapeutic purposes
To designate the probable most important differentially expressed genes and genetic pathways in Wilms tumor and assess their expression and...
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Identification of RNF150 as the hub gene associated with microsatellite instability in gastric cancer
Gastric cancer (GC) is a common digestive tract malignancy with the sixth global incidence and third cancer-related deaths, respectively....
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Validation of the Idylla GeneFusion assay to detect fusions and MET exon-skip** in non-small cell lung cancers
Gene fusions and MET exon skip** drive oncogenesis in 8–9% and 3% of non-small cell lung cancers (NSCLC) respectively. Their detection are...
