Search
Search Results
-
Serum inflammatory biomarkers are associated with increased choroidal thickness in keratoconus
Inflammation may play a significant role in Keratoconus (KC), but the relationship between inflammatory markers and choroidal thickness (CT) is...
-
Immunomodulatory response in an experimental model of brain death
Liver transplantation has come a long way and is now regarded as the gold standard treatment for end-stage liver failure. The great majority of...
-
Glucocorticoids’ treatment impairs the medium-term immunogenic response to SARS-CoV-2 mRNA vaccines in Systemic Lupus Erythematosus patients
Limited data exists on SARS-CoV-2 sustained-response to vaccine in patients with rheumatic diseases. This study aims to evaluate neutralizing...
-
Sparsely methylated mitochondrial cell free DNA released from cardiomyocytes contributes to systemic inflammatory response accompanied by atrial fibrillation
Systemic inflammation is assumed to be the consequence and the cause of atrial fibrillation (AF); however, the underlying mechanism remains unclear....
-
Sepsis modulates cortical excitability and alters the local and systemic hemodynamic response to seizures
Non-convulsive seizures and status epilepticus are frequent and associated with increased mortality in septic patients. However, the mechanism...
-
Steroid treatment suppresses the CD4+ T-cell response to the third dose of mRNA COVID-19 vaccine in systemic autoimmune rheumatic disease patients
Prolonged steroid treatment has a suppressive effect on the immune system, however, its effect on the cellular response to mRNA vaccine is unknown....
-
Evodiae Fructus extract suppresses inflammatory response in HaCaT cells and improves house dust mite-induced atopic dermatitis in NC/Nga mice
This study was conducted to assess the effect of Evodiae Fructus 70% ethanol extract (EFE) on the pathology of atopic dermatitis using in vitro and...
-
Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice
Toll-like receptor 9 (TLR9) recognizes self-DNA and plays intricate roles in systemic lupus erythematosus (SLE). However, the molecular mechanism...
-
A cross-sectional National Health and Nutrition Examination survey-based study of the association between systemic immune-inflammation index and blood urea nitrogen levels in United States adolescents
Blood urea nitrogen (BUN) level is one of the commonly used indicators to assess renal function and systemic immune-inflammatory status. In the...
-
Mass spectrometry analysis of gut tissue in acute SIV-infection in rhesus macaques identifies early proteome alterations preceding the interferon inflammatory response
HIV infection damages the gut mucosa leading to chronic immune activation, increased morbidities and mortality, and antiretroviral therapies, do not...
-
Dietary fatty acids differentially affect secretion of pro-inflammatory cytokines in human THP-1 monocytes
Monocytes are a major population of circulating immune cells that play a crucial role in producing pro-inflammatory cytokines in the body. The...
-
A single-arm, open-label pilot study of neuroimaging, behavioral, and peripheral inflammatory correlates of mindfulness-based stress reduction in multiple sclerosis
Multiple sclerosis (MS) is a chronic neurological disease frequently associated with significant fatigue, anxiety, depression, and stress. These...
-
Metformin selectively dampens the acute inflammatory response through an AMPK-dependent mechanism
Metformin is a first-line drug in the treatment of type-2 diabetes mellitus (T2DM). In addition to its antigluconeogenic and insulin-sensitizing...
-
Kaempferol mitigates reproductive dysfunctions induced by Naja nigricollis venom through antioxidant system and anti-inflammatory response in male rats
Naja nigricollis Venom (NnV) contains complex toxins that affects various vital systems functions after envenoming. The venom toxins have been...
-
Muscle mass as a modifier of stress response in acute ischemic stroke patients
Stroke triggers a systemic inflammatory response over the ensuing days after the cerebral insult. The age and comorbidities of the stroke population...
-
Central role for neurally dysregulated IL-17A in dynamic networks of systemic and local inflammation in combat casualties
Dynamic Network Analysis (DyNA) and Dynamic Hypergraphs (DyHyp) were used to define protein-level inflammatory networks at the local (wound effluent)...
-
Promotion of the inflammatory response in mid colon of complement component 3 knockout mice
To determine whether complement component 3 (C3) deficiency affects its receptor downstream-mediated inflammatory response, the current study was...
-
Osteoblast/osteocyte-derived interleukin-11 regulates osteogenesis and systemic adipogenesis
Exercise results in mechanical loading of the bone and stimulates energy expenditure in the adipose tissue. It is therefore likely that the bone...
-
A break in mitochondrial endosymbiosis as a basis for inflammatory diseases
Mitochondria retain bacterial traits due to their endosymbiotic origin, but host cells do not recognize them as foreign because the organelles are...
-
Exploring the association between dietary Inflammatory Index and chronic pain in US adults using NHANES 1999–2004
Chronic pain, a substantial public health issue, may be influenced by dietary patterns through systemic inflammation. This cross-sectional study...
