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Proof of principle study: synchrotron X-ray fluorescence microscopy for identification of previously radioactive microparticles and elemental map** of FFPE tissues
Biobanks containing formalin-fixed, paraffin-embedded (FFPE) tissues from animals and human atomic-bomb survivors exposed to radioactive particulates...
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A proof of concept for a deep learning system that can aid embryologists in predicting blastocyst survival after thaw
The ability to understand whether embryos survive the thaw process is crucial to transferring competent embryos that can lead to pregnancy. The...
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A multicenter proof-of-concept study on deep learning-based intraoperative discrimination of primary central nervous system lymphoma
Accurate intraoperative differentiation of primary central nervous system lymphoma (PCNSL) remains pivotal in guiding neurosurgical decisions....
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A graph-based approach can improve keypoint detection of complex poses: a proof-of-concept on injury occurrences in alpine ski racing
For most applications, 2D keypoint detection works well and offers a simple and fast tool to analyse human movements. However, there remain many...
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Another operator-theoretical proof for the second-order phase transition in the BCS-Bogoliubov model of superconductivity
In the preceding papers, imposing certain complicated and strong conditions, the present author showed that the solution to the BCS-Bogoliubov gap...
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Do** of casted silk fibroin membranes with extracellular vesicles for regenerative therapy: a proof of concept
Bioactive material concepts for targeted therapy have been an important research focus in regenerative medicine for years. The aim of this study was...
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Virtual reality to understand pain-associated approach behaviour: a proof-of-concept study
Pain-associated approach and avoidance behaviours are critically involved in the development and maintenance of chronic pain. Empirical research...
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A non-invasive capacitive sensor to investigate the Leidenfrost phenomenon: a proof of concept study
A volatile sessile liquid droplet or a sublimating solid manifests levitation on its own vapor when placed on a sufficiently heated surface,...
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PET imaging of mitochondrial function in acute doxorubicin-induced cardiotoxicity: a proof-of-principle study
Mitochondrial dysfunction plays a key role in doxorubicin-induced cardiotoxicity (DIC). In this proof-of-principle study, we investigated whether PET...
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Proof of concept for multiplex amplicon sequencing for mutation identification using the MinION nanopore sequencer
Rapid, cost-effective identification of genetic variants in small candidate genomic regions remains a challenge, particularly for less well equipped...
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A pseudovirus-based platform to measure neutralizing antibodies in Mexico using SARS-CoV-2 as proof-of-concept
The gold-standard method to evaluate a functional antiviral immune response is to titer neutralizing antibodies (NAbs) against a viral pathogen. This...
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Semantic representation and comparative analysis of physical activity sensor observations using MOX2-5 sensor in real and synthetic datasets: a proof-of-concept-study
The widespread use of devices like mobile phones and wearables allows for automatic monitoring of human daily activities, generating vast datasets...
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Proof of concept and early development stage of market-oriented high iron and zinc rice expressing dicot ferritin and rice nicotianamine synthase genes
Micronutrient deficiencies such as iron (Fe), zinc (Zn), and vitamin A, constitute a severe global public health phenomenon. Over half of preschool...
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A proof-of-concept study to construct Bayesian network decision models for supporting the categorization of sudden unexpected infant death
Sudden infant death syndrome (SIDS) remains a leading cause of infant death in high-income countries. Supporting models for categorization of sudden...
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A proof of concept for machine learning-based virtual knap** using neural networks
Prehistoric stone tools are an important source of evidence for the study of human behavioural and cognitive evolution. Archaeologists use insights...
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Proof of concept nanotechnological approach to in vitro targeting of malignant melanoma for enhanced immune checkpoint inhibition
Immunotherapies, including immune checkpoint inhibitors, have limitations in their effective treatment of malignancies. The immunosuppressive...
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Classifying autism in a clinical population based on motion synchrony: a proof-of-concept study using real-life diagnostic interviews
Predictive modeling strategies are increasingly studied as a means to overcome clinical bottlenecks in the diagnostic classification of autism...
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Prediction of anastomotic insufficiency based on the mucosal microbiome prior to colorectal surgery: a proof-of-principle study
Anastomotic leakage (AL) is a potentially life-threatening complication following colorectal cancer (CRC) resection. In this study, we aimed to...
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Optical imaging spectroscopy for rapid, primary screening of SARS-CoV-2: a proof of concept
Effective testing is essential to control the coronavirus disease 2019 (COVID-19) transmission. Here we report a-proof-of-concept study on...
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Proof of crystal-field-perturbation-enhanced luminescence of lanthanide-doped nanocrystals through interstitial H+ do**
Crystal-field perturbation is theoretically the most direct and effective method of achieving highly efficient photoluminescence from trivalent...
