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Ethical and coordinative challenges in setting up a national cohort study during the COVID-19 pandemic in Germany
With the outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), global researchers were confronted with major challenges. The...
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Knowledge, attitudes, and practices of the ethics in medical research among Moroccan interns and resident physicians
BackgroundIn Morocco, medical research ethics training was integrated into the medical curriculum during the 2015 reform. In the same year, a law on...
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Physicians’ attitudes in relation to end-of-life decisions in Neonatal Intensive Care Units: a national multicenter survey
BackgroundEnd-of-life decisions for neonates with adverse prognosis are controversial and raise ethical and legal issues. In Greece, data on...
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Comparison of the end-of-life decisions of patients with hospital-acquired pneumonia after the enforcement of the life-sustaining treatment decision act in Korea
BackgroundAlthough the Life-Sustaining Treatment (LST) Decision Act was enforced in 2018 in Korea, data on whether it is well established in actual...
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Normative framework of informed consent in clinical research in Germany, Poland, and Russia
BackgroundBiomedical research nowadays is increasingly carried out in multinational and multicenter settings. Due to disparate national regulations...
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Beyond translations, perspectives for researchers to consider to enhance comprehension during consent processes for health research in sub-saharan Africa: a sco** review
BackgroundLiterature on issues relating to comprehension during the process of obtaining informed consent (IC) has largely focused on the challenges...
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Exploring moral competence regression: a narrative approach in medical ethics education for medical students
BackgroundStudies from different countries report a stagnation or regression of moral competence in medical students between the first and the last...
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Research Ethics and Research Ethics Committees in Europe
In Europe, the topics of “research ethics” and “ethics committees” are becoming increasingly present in publications, university seminars, public...
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Ethical considerations for biobanking and use of genomics data in Africa: a narrative review
BackgroundBiobanking and genomic research requires collection and storage of human tissue from study participants. From participants’ perspectives...
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Personalized Treatments: Where Patient’s History and Biological Background Meet
Current studies on “personalized medicine” focus prevalently on network-based models of genome function. Since the eighties, the agenda of...
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How Competition for Funding Impacts Scientific Practice: Building Pre-fab Houses but no Cathedrals
In the research integrity literature, funding plays two different roles: it is thought to elevate questionable research practices (QRPs) due to...
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Case Studies of Global Governance for Health Research
This chapter is specified to a number of case studies to portray the challenges of Global Health Governance and Global Governance for Health Research...
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Unapproved clinical trials in Russia: exception or norm?
BackgroundIn modern Russia, any clinical investigation of a pharmaceutical for use in humans is subject to prior evaluation and approval by the...
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Development and validation of a tool to assess researchers’ knowledge of human subjects’ rights and their attitudes toward research ethics education in Saudi Arabia
BackgroundResearchers must adhere to ethical and scientific standards in their research involving human subjects; therefore, their knowledge of human...
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Oncologists’ perspective on advance directives, a French national prospective cross-sectional survey – the ADORE study
BackgroundThe often poor prognosis associated with cancer necessitates empowering patients to express their care preferences. Yet, the prevalence of...
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Relevance of Precision Medicine in Public Health Genomics and Global Health Genomics
Precision Medicine (PM) is anticipated to have significant impact on individual health, public health and global health. With advances in sequencing...
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Does teaching medical ethics ensure good knowledge, attitude, and reported practice? An ethical vignette-based cross-sectional survey among doctors in a tertiary teaching hospital in Nepal
BackgroundImportance of awareness of medical ethics and its integration into medical curriculum has been frequently highlighted. Study 1 aimed to...
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Institutional review boards in Saudi Arabia: the first survey-based report on their functions and operations
BackgroundInstitutional review boards (IRBs) are formally designated to review, approve, and monitor biomedical research. They are responsible for...
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Relevance of PM in Infectious and Non-communicable Chronic Diseases and Pandemics
Precision medicine (PM) in the form of Pharmacogenomics (PGx) promises the use of diagnostic testing to provide the best clinical decisions based on...
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Identifying facilitators of and barriers to the adoption of dynamic consent in digital health ecosystems: a sco** review
BackgroundConventional consent practices face ethical challenges in continuously evolving digital health environments due to their static, one-time...
