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Solid-Phase Fluorimetric Determination of Some Nonsteroidal Anti-Inflammatory Drugs in Medicines with the Aid of a Smartphone
A fast and simple method for determining the active ingredients of non-steroidal anti-inflammatory drugs (NSAIDs) meloxicam and tolfenamic,...
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Evaluation of the knowledge, practices, and attitudes of community pharmacists towards adverse effects of non-steroidal anti-inflammatory drugs (NSAIDs): a cross-sectional study
BackgroundNonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly used over-the-counter medications for the treatment of pain, fever, and...
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Structural Features and Anti-Inflammatory Activity of 13-(N-Arylaminocarbonyl)-9-Methyl-11-Thioxo-8-Oxa-10,12-Diazatricyclo-[7.3.1.02,7]Trideca-2,4,6-Trienes and Their 10-N-Phenyl-Substituted Derivatives
A study of the structural features and anti-inflammatory activity of 13-( N -arylaminocarbonyl)-9-methyl-11-thioxo-8-oxa-10,12-diazatricyclo[7.3.1.0 2,7 ]...
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Nanoemulsion Improves the Anti-inflammatory Activity of Carvacrol upon Oral Administration
Carvacrol is the main phenolic monoterpene isolated from the essential oils of plants from the genus Origanum L., Lamiaceae. Carvacrol has several...
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Anti-Inflammatory, Wound Healing, and Hepatoprotective Effects of Ethanol Extract of Rice Bran in Rodent Models
Rice bran is an essential co-product in rice meals with many biological activities. This study was aimed at evaluating the anti-inflammatory, wound...
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Synthesis of 5,5′-(Disulfanediyl)bis[3-phenyl-1,3,4-thiadiazole-2(3H)-thione] and Study of Its Anti-Inflammatory Activity
5,5′-(Disulfanediyl)bis[3-phenyl-1,3,4-thiadiazole-2(3 H )-thione] was synthesized by oxidative condensation in the presence of chloride ions. The...
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Anti-Inflammatory and Analgesic Activity of Ethanolic Extract of Tubers and Different Fractions of Eulophia nuda Lindl.
Recently, in human and animal diseases, inflammation and pain have become the focus of scientific research as it affects more people than any other...
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Anti-inflammatory Activity of Total Alkaloids in Nelumbo nucifera and Simultaneous Determination of Major Bisbenzylisoquinolines
Plumula nelumbinis , the green embryo of the mature seeds of Nelumbo nucifera Gaertn., Nelumbonaceae, is widely used in traditional Chinese medicine...
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Synthesis and Investigation of Antinociceptive, Anti-Inflammatory, and Ulcerogenic Potential of L-Tryptophan and L-Proline Sulfamide Derivatives
The aim of this work was to study the systemic antinociceptive and anti-inflammatory effects and to evaluate the gastropathic effects of L -proline...
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Anti-inflammatory and Antinociceptive Potential of Verbascum latisepalum
Verbascum L. species are mainly used for inflammatory diseases and against malaria in traditional medicine. Therefore, we aimed to assess the in vivo ...
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Role of proteinase-activated receptors 1 and 2 in nonsteroidal anti-inflammatory drug enteropathy
BackgroundThe use of nonsteroidal anti-inflammatory drugs (NSAIDs) can promote lower gastrointestinal detrimental effects. Proteinase-activated...
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Potential of natural products in inflammation: biological activities, structure–activity relationships, and mechanistic targets
A balance between the development and suppression of inflammation can always be found in the body. When this balance is disturbed, a strong...
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Evaluation of analgesic and anti-inflammatory activity of purine-2,6-dione-based TRPA1 antagonists with PDE4/7 inhibitory activity
BackgroundTo verify the validity of the proposed pain treatment approach, which is based on concomitant blocking of the Transient Receptor Potential...
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Potential drugs for the treatment of Alzheimer’s disease
It is well known that amyloid precursor protein (APP), the enzyme β-secretase 1 (BACE1), cyclooxygenase 2 (COX-2), nicastrin (NCT), and...
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Anti-inflammatory Clerodane Dinorditerpenoids from the Tinospora sinensis Leaves
Using various chromatographic methods, one new clerodane dinorditerpenoid, tinosinodane, and fourteen known compounds, tinosposinenside C,...
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Synthesis and Anti-Inflammatory Activity of N,6-Diaryl-4-Methyl-2-Thioxo-1,2,3,6-Tetrahydropyrimidine-5-Carboxamides
Previously unreported N ,6-Diaryl-4-methyl-2-thioxo-1,2,3,6-tetrahydropyrimidine-5-carboxamides were synthesized by reacting acetoacetanilides with a...
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Benefits and Risks of Nonsteroidal Anti-inflammatory Drugs: Methodologic Limitations Lead to Clinical Uncertainties
Nonsteroidal anti-inflammatory drugs (NSAIDs) include traditional (tNSAIDs), such as ibuprofen, naproxen, and diclofenac, as well as selective...
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Lipid-lowering drugs and cancer: an updated perspective
Statins and non-statin medications used for the management of dyslipidemia have been shown to possess antitumor properties. Since the use of these...
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Glycoalkaloids of Plants in the Family Solanaceae (Nightshade) as Potential Drugs
Worldwide interest in medicinal plants and related drugs is growing because of the increased spectrum of new synthetic drugs. In this context,...
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Be wary of adverse events when considering pharmacotherapies for spine-related pain in elderly patients
Take care when considering pharmacotherapy for spine-related pain in elderly patients as drug-related adverse events are more likely to occur and to...