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Evaluation of the knowledge, practices, and attitudes of community pharmacists towards adverse effects of non-steroidal anti-inflammatory drugs (NSAIDs): a cross-sectional study
BackgroundNonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly used over-the-counter medications for the treatment of pain, fever, and...
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Solid-Phase Fluorimetric Determination of Some Nonsteroidal Anti-Inflammatory Drugs in Medicines with the Aid of a Smartphone
A fast and simple method for determining the active ingredients of non-steroidal anti-inflammatory drugs (NSAIDs) meloxicam and tolfenamic,...
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Synthesis of 5,5′-(Disulfanediyl)bis[3-phenyl-1,3,4-thiadiazole-2(3H)-thione] and Study of Its Anti-Inflammatory Activity
5,5′-(Disulfanediyl)bis[3-phenyl-1,3,4-thiadiazole-2(3 H )-thione] was synthesized by oxidative condensation in the presence of chloride ions. The...
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Synthesis and Investigation of Antinociceptive, Anti-Inflammatory, and Ulcerogenic Potential of L-Tryptophan and L-Proline Sulfamide Derivatives
The aim of this work was to study the systemic antinociceptive and anti-inflammatory effects and to evaluate the gastropathic effects of L -proline...
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Anti-inflammatory and Antinociceptive Potential of Verbascum latisepalum
Verbascum L. species are mainly used for inflammatory diseases and against malaria in traditional medicine. Therefore, we aimed to assess the in vivo ...
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Role of proteinase-activated receptors 1 and 2 in nonsteroidal anti-inflammatory drug enteropathy
BackgroundThe use of nonsteroidal anti-inflammatory drugs (NSAIDs) can promote lower gastrointestinal detrimental effects. Proteinase-activated...
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Potential of natural products in inflammation: biological activities, structure–activity relationships, and mechanistic targets
A balance between the development and suppression of inflammation can always be found in the body. When this balance is disturbed, a strong...
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Potential drugs for the treatment of Alzheimer’s disease
It is well known that amyloid precursor protein (APP), the enzyme β-secretase 1 (BACE1), cyclooxygenase 2 (COX-2), nicastrin (NCT), and...
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Benefits and Risks of Nonsteroidal Anti-inflammatory Drugs: Methodologic Limitations Lead to Clinical Uncertainties
Nonsteroidal anti-inflammatory drugs (NSAIDs) include traditional (tNSAIDs), such as ibuprofen, naproxen, and diclofenac, as well as selective...
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Synthesis and Anti-Inflammatory Activity of N,6-Diaryl-4-Methyl-2-Thioxo-1,2,3,6-Tetrahydropyrimidine-5-Carboxamides
Previously unreported N ,6-Diaryl-4-methyl-2-thioxo-1,2,3,6-tetrahydropyrimidine-5-carboxamides were synthesized by reacting acetoacetanilides with a...
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Be wary of adverse events when considering pharmacotherapies for spine-related pain in elderly patients
Take care when considering pharmacotherapy for spine-related pain in elderly patients as drug-related adverse events are more likely to occur and to...
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Pharmacological Properties of Acetylsalicylic Acid and its Complex with Glycyrrhizic Acid as a Promising Dosage form (Review)
The review summarizes current literature data on the mechanism of antithrombotic, anti-inflammatory, and antipyretic effects of acetylsalicylic acid...
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A multidisciplinary approach to verify and de-label of drug allergic histories in a university hospital in Thailand: a retrospective descriptive study
BackgroundMislabeling of drug allergic histories causes avoidable negative impacts on patients and healthcare system. Although multidisciplinary...
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Lipid-lowering drugs and cancer: an updated perspective
Statins and non-statin medications used for the management of dyslipidemia have been shown to possess antitumor properties. Since the use of these...
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Immunochemical Determination of Diclofenac in Tablets, Artificial Urine, and Surface Water Using Ruthenium and Rhenium Complexes
Methods using fluorescence polarization analysis and an amperometric immunosensor for the immunochemical determination of the non-steroidal...
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Role of Natural Flavonoid Products in Managing Osteoarthritis
Flavonoids belong to a subgroup of polyphenol bioactive compounds of plant origin. They are a topic of interest for their anti-inflammatory and...
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Ternary Solid Dispersion of Celecoxib Produced by the Solvent Method with Improved Solubility and Dissolution Properties
Celecoxib, the first cyclooxygenase-2 selective nonsteroidal anti-inflammatory drug, has a wide range of pharmacological effects, including...
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Synthesis and Anti-Inflammatory and Antiulcer Activity of a Glycyrrhizic Acid Conjugate with L-Phenylalanine Methyl Ester
A conjugate of glycyrrhizic acid (GA) with L-phenylalanine methyl ester was synthesized using N -hydroxysuccinimide and...
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Using Liposomal and Intranasal Drugs and Pioglitazone for the Treatment and Prevention of Alzheimer’s Disease (Review)
This review article provides information on the development of liposomal drug delivery systems to cross the blood(brain barrier (BBB). Information on...
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Formulation and Evaluation of Tamarind Seed Polysaccharide Gel for the Controlled Delivery of Aceclofenac
The purpose of this study was to develop a transdermal gel with the addition of different polymer ratios that incorporates 1.0 %w/w aceclofenac to...
