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Cytotoxic Plumbagin-5-O-α-l-Rhamnopyranoside from Plumbago indica
The chemical investigation of Plumbago indica L., Plumbaginaceae, has led to isolation and identification of one new naphthoquinone glycoside...
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Potential of natural products in inflammation: biological activities, structure–activity relationships, and mechanistic targets
A balance between the development and suppression of inflammation can always be found in the body. When this balance is disturbed, a strong...
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Vitamin K: a Potential Neuroprotective Agent
Neurodegeneration, a progressive disease due to the arrested development of atrophy and regression of neuron function, is the most common disorder...
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A Novel Compound from the Bark of Diospyros lotus and their Urease Inhibitory Activity
One novel dimeric naphthoquinone, 1′,4′-dihydroxy-5,8-dimethoxy-11,11′-dimethyl-[7,3′-binaphthalene]-1,4,5′,8′-tetraone, was isolated from the...
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Synthesis of Natural Product Derivatives as Larvicides Against Aedes aegypti
Larvicides are pesticides that kill insects during their early life stages. Aedes aegypti (Linnaeus, 1762), Diptera: Culicidae, usually breed in...
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Current Advancements for New Drug Discovery Against Dengue Virus: A Review (2015 – 2020)
Dengue fever is a viral ailment mostly found in tropical and sub-tropical communities. Dengue fever is spread by the mosquito Aedes aegypti....
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Anthraquinone and Naphthoquinone Derivatives from the Pericarps of Juglans sigillata
Four new anthraquinones ( 1–4 ), along with four known ones ( 5–8 ) and five known naphthoquinones ( 9–13 ), were isolated from the green pericarps of...
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Lawsonol, a New Bioactive Naphthoquinone Dimer From the Leaves of Lawsonia alba
A new bioactive naphthoquinone dimer, lawsonol[2-(1,4-dioxo-1,4-dihydronaphthalen-2-yloxy)-3-hydroxynaphthalene-1,4-dione] ( 1 ), was isolated from the...
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Lung Cancer-Targeted [131I]-Iodoshikonin as Theranostic Agent: Radiolabeling, In Vivo Pharmacokinetics and Biodistribution
Shikonin has been reported to exhibit high affinity toward lung cells and recited to inhibit the migration and invasion of lung cancer cells and...
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HPLC Determination of Myricitrin in Juglans nigra L. Bark
An HPLC method for quantitative determination of myricitrin in black walnut ( Julgans nigra L.) bark was developed. The content of the dominant...
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DISCUSSION OF HERBAL DRUGS BASED ON THE BIOGENETIC CLASSIFICATION OF THEIR MAIN ACTIVE COMPONENTS
Honey is prepared by honey-bees (Apis mellifera) from the nectar and honeydew of flowers. After chemical conversion by the gastric juices in the...
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Physicochemical Properties and Methods of Analysis of Vildagliptin (Review)
Vildagliptin is an oral agent which is a member of a new class of hypoglycemic drugs, dipeptidylpeptidase-4 (DPP-4) inhibitors. This review presents...
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Advances in plant-derived natural products for antitumor immunotherapy
In recent years, immunotherapy has emerged as a novel antitumor strategy in addition to traditional surgery, radiotherapy and chemotherapy. It...
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BIOSYNTHESIS OF PLANT SUBSTANCES; BIOGENETIC RELATIONSHIPS
The bioactive substances in medicinal plants will be discussed on the basis of their chemical structure, or more precisely, of a...
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Plumbagin engenders apoptosis in lung cancer cells via caspase-9 activation and targeting mitochondrial-mediated ROS induction
Plumbagin is a naturally-derived phytochemical which exhibits promising medicinal properties, including anticancer activities. In the present study,...
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Nutraceuticals Derived from Dietary Spices as Candidate Molecules in Targeting Glioma Signaling Pathways
Spices have been used by people for generations as a source of food flavors to increase culinary delicacy. These ingredients not only give the food...
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Antimicrobial compounds from marine actinomycetes
Marine actinomycetes were the main origin of marine natural products in the past 40 years. This review was to present the sources, structures and...
