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Secondary Metabolites of Oplopanax elatus: Possibilities for Standardization of a Multiphytoadaptogen for Preventive Oncology
An herbal formulation of a multiphytoadaptogen (MPA) developed at the N. N. Blokhin Cancer Center and containing phytocomponents from Oplopanax elatus ...
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Pharmacokinetics of ginsenosides following repeated oral administration of red ginseng extract significantly differ between species of experimental animals
We aimed to investigate ginsenoside pharmacokinetics in mice and rats following the repeated oral administration of red ginseng extract (RGE)...
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Mitochondrial connection to ginsenosides
Mitochondria play an essential role in energy synthesis and supply, thereby maintaining cellular function, survival, and energy homeostasis via...
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Therapeutic effects of ginsenosides on breast cancer growth and metastasis
Breast cancer is the most common cause of cancer-related deaths among women worldwide. Thus, the development of new and effective low-toxicity drugs...
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Ginsenoside Rg5 as an anticancer drug: a comprehensive review on mechanisms, structure–activity relationship, and prospects for clinical advancement
Cancer remains one of the leading causes of death in the world. Despite the considerable success of conventional treatment strategies, the incidence...
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Ginsenoside from ginseng: a promising treatment for inflammatory bowel disease
Inflammatory bowel disease (IBD) is an autoimmune disease mediated by immune disorder and termed as one of the most refractory diseases by the Word...
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A Potential Method for Standardization of Multiphytoadaptogen: Tandem Mass Spectrometry for Analysis of Biologically Active Substances from Rhodiola rosea
Tandem mass spectrometry (HPLC-MS/MS) was used to analyze biologically active compounds in extracts of the tuber and roots of Rhodiola rosea (family Crassulaceae...
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Analysis of Eleutherosides by Tandem Mass Spectrometry: Possibilities of Standardizing a Multi-Phytoadaptogen Formulation for Preventive Oncology
The major bioactive constituents in extracts from roots of Eleutherococcus senticosus (Rupr. & Maxim) (Araliaceae) and in a multi-adaptogen herbal...
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Neurological disorders of COVID-19: insights to applications of natural products from plants and microorganisms
In addition to the typical respiratory manifestations, various disorders including involvement of the nerve system have been detected in COVID-19...
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Interactions of ginseng with therapeutic drugs
Ginseng is the most frequently used herbal medicine for immune system stimulation and as an adjuvant with prescribed drugs owing to its numerous...
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DISCUSSION OF HERBAL DRUGS BASED ON THE BIOGENETIC CLASSIFICATION OF THEIR MAIN ACTIVE COMPONENTS
Honey is prepared by honey-bees (Apis mellifera) from the nectar and honeydew of flowers. After chemical conversion by the gastric juices in the...
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Ultrasonication processed Panax ginseng berry extract induces apoptosis through an intrinsic apoptosis pathway in HepG2 cells
Ginseng’s major active components, ginsenosides, have been known to show anti-cancer, neuroprotective, and anti-inflammatory activities....
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Biotransformation of Ginsenosides Re and Rg1 by the Bacterium Microbacterium sp. GT35
The bacterium Microbacterium sp. GT35 was found to be capable of transforming Re and Rg 1 , principal ginsenosides of the 20(S)-protopanaxatriol...
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Anticonvulsant mechanism of saponins fraction from adventitious roots of Ficus religiosa: possible modulation of GABAergic, calcium and sodium channel functions
In our previous studies, quantified saponins-rich fraction from adventitious root extract of Ficus religiosa L., Moraceae, showed anticonvulsant...
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Biotransformation of the Principal Ginsenosides of Panax ginseng Into Minor Glycosides Through the Action of Bacterium Paenibacillus sp. BG134
The bacterium Paenibacillus sp. BG134 was capable of biotransforming the principal 20(S)-protopanaxadiol ginsenosides Rc, Rb 2 , Rd, and Rb 1 into the...
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Tissue distribution and excretion of herbal components after intravenous administration of a Chinese medicine (Shengmai injection) in rat
Shengmai injection, consisting of Panax ginseng , Radix ophiopogonis and Schisandra chinensis , is a widely used Chinese medicine for the treatment of...
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Preparation and characterization of mucoadhesive enteric-coating ginsenoside-loaded microparticles
Ginsenoside saponins are phytochemically extracted from red ginseng and have been regarded as the principal components manifesting the pharmacologic...
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Ginsenoside compound K inhibits angiogenesis via regulation of sphingosine kinase-1 in human umbilical vein endothelial cells
Ginsenoside compound K (CK) is a metabolite of the protopanaxadiol-type saponins of Panax ginseng C.A. Meyer (Araliaceae), has long been used to...
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