Search
Search Results
-
Shionone Relieves Ulcerative Colitis by Regulating the p38 MAPK/NF-κB Pathway
Ulcerative colitis is a serious intestinal disorder, which can lead to a variety of complications, and in severe cases, the risk of becoming...
-
The Role of Lycium barbarum (Goji Berry) in Apoptosis and Autophagy in the Experimental Ulcerative Colitis Model
Ulcerative colitis is one of the most common intestinal diseases in the world. Lycium barbarum (Goji Berry) is a type of fruit that is frequently...
-
Age is just a number with ulcerative colitis therapies
Limited data suggest that older patients with ulcerative colitis (UC) irrespective of late-onset UC or disease diagnosed before the age of 60 years,...
-
Ionically bridged dexamethasone sodium phosphate–zinc–PLGA nanocomplex in alginate microgel for the local treatment of ulcerative colitis
Colon-targeted oral drug delivery systems comprising nanoparticles and microparticles have emerged as promising tools for the treatment of ulcerative...
-
Influence of Biologically Active Peptides on the Course of Experimental Ulcerative Colitis
The lipid-transfer protein Ns-LTP1 was isolated from Nigella sativa seeds using a complex of chromatographic methods. Its effect on the course of...
-
In-Silico Study, Preparation and Biological Evaluation of 99MTC-Mesalamine Complex as Radiotracer for Diagnostics and Monitoring of Ulcerative Colitis in Mice
This work centralizes on pursuit ulcerative colitis localized in mice. High radiolabeling and purity were ensured during the formation of a...
-
Indole-3-acetic acid ameliorates dextran sulfate sodium-induced colitis via the ERK signaling pathway
Microbiota-derived catabolism of nutrients is closely related to ulcerative colitis (UC). The level of indole-3-acetic acid (IAA), a...
-
Subcutaneous vedolizumab in moderately to severely active ulcerative colitis or Crohn’s disease: a profile of its use
Vedolizumab (Entyvio ® ), a humanized monoclonal antibody targeting the α4β7 integrin, is effective and generally well tolerated as an induction and...
-
Tofacitinib in ulcerative colitis: a profile of its use
Oral tofacitinib (Xeljanz ® ) is a first-in-class, small molecule janus kinase (JAK) inhibitor that is approved for the treatment of moderate to severe...
-
A derivative of 3-(1,3-diarylallylidene)oxindoles inhibits dextran sulfate sodium-induced colitis in mice
BackgroundIA-0130 is a derivative of 3-(1,3-diarylallylidene)oxindoles, which is a selective estrogen receptor modulator (SERM). A previous study...
-
New gold(III) complexes TGS 121, 404, and 702 show anti-tumor activity in colitis-induced colorectal cancer: an in vitro and in vivo study
BackgroundChronic inflammation in the course of inflammatory bowel disease may result in colon cancer, or colitis-associated colorectal cancer...
-
When managing ulcerative colitis in older patients, understanding their overall health profile is key
Ulcerative colitis (UC) in patients aged > 60 years is increasingly common. The treatment of UC aims to induce and maintain clinical remission, with...
-
Therapeutic Effects of Resveratrol in Inflammatory Bowel Diseases: Shedding Light on the Role of Cellular and Molecular Pathways
Inflammatory bowel disease is a debilitating idiopathic inflammatory condition of the gastrointestinal tract. Generally, this illness contains two...
-
Anti-inflammatory and antibacterial effects of human cathelicidin active fragment KR-12 in the mouse models of colitis: a novel potential therapy of inflammatory bowel diseases
IntroductionInflammatory bowel diseases (IBD) are a group of chronic gastrointestinal tract disorders with complex etiology, with intestinal...
-
The association of the quality of sleep with proinflammatory cytokine profile in inflammatory bowel disease patients
BackgroundThe role of circadian rhythm abnormalities in patients with inflammatory bowel disease (IBD) remains relatively unknown. The aim of this...
-
The Antioxidant Activity and the Protective Effect of Rosa canina L. Fruit Against Intestinal Inflammation Induced by Hyperhomocysteinemia in Mice
Inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, are immune-mediated chronic inflammatory diseases of the...
-
Treatments of inflammatory bowel disease toward personalized medicine
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), is a chronic inflammatory disease characterized by...
-
Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives
Sophora is deemed as one of the most remarkable genera of Fabaceae, and the third largest family of flowering plants. The genus Sophora comprises...
-
Organ-Based Medicine
The core problem of both medicine and all biomedical research, which would also exist if all research had become reproducible, statistically correct,...