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Brazilian Medicinal Plants with Antiamyloidogenic Activity
Amyloid fibrillation is a process involved in a large set of pathologies, including diabetes and Alzheimer’s. Although Brazil has a large...
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Chemical Composition of Flowers of Yucca elephantipes Cultivated in Georgia
Three sesquiterpene glycosides, i.e., nerolidol derivatives, and steroidal glycosides of the 3-furostanol and 1-spirostanol series, one of which was...
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Chemical Compositions and Pharmacological Activities of Iberis amara L. (A Review)
Iberis amara L. belongs to the family of Brassicaceae, which is native to Southern Europe. It is a bloomer cultivated as an ornamental and medicinal...
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A New 26-Norlanostanoid from the Fruiting Bodies of Ganoderma philippii
A new nortriterpenoid, 26-nor-11,22-dioxolanost-8-en-3β,7β,15α-triol ( 1 ), was isolated from the EtOAc extract of the fruiting bodies of Ganoderma...
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In Vitro Cytotoxic Potential of Ethanol Extract of Dictyopteris acrostichoides Against Human Cancer Cells
Ethanol extracts of Caulerpa racemose (Forsskål) J.Agardh, 1873, Dictyopteris acrostichoides (J.Agardh) Bornet, 1885, Halimeda opuntia (Linnaeus)...
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Lipoxygenase and α-Glucosidase Inhibitory Constituents of Phlomis stewartii
Two new sphingolipids, stewartins A: [(2S,3S,4R)-2-{[(2R,11E)-2-hydroxyoctadec-11-enoyl]amino}tetraeicosane-1,3,4-triol-1- O - β -D-glucopyranoside, 1 ]...
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Cytotoxic Isopimarane Diterpenoids from Kaempferia koratensis Rhizomes
Two new isopimarane diterpenoids, koratanes A and B, were identified from the rhizomes of Kaempferia koratensis Picheans., Zingiberaceae, together...
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Pharmacokinetics of ginsenosides following repeated oral administration of red ginseng extract significantly differ between species of experimental animals
We aimed to investigate ginsenoside pharmacokinetics in mice and rats following the repeated oral administration of red ginseng extract (RGE)...
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Triterpenoids from Dysoxylum genus and their biological activities
This study aims to analyze the ethnobotanical, chemical, and biological activities of triterpenoid compounds isolated from the Dysoxylum genus of the...
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Phytochemistry and pharmacology of plants in the genus Chaenomeles
Chaenomeles plants belong to the Rosaceae family and include five species, Chaenomeles speciosa (Sweet) Nakai, Chaenomeles sinensis (Thouin) Koehne, Ch...
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Ginkwanghols A and B, osteogenic coumaric acid-aliphatic alcohol hybrids from the leaves of Ginkgo biloba
Ginkgo biloba (Ginkgoaceae), commonly known as “ginkgo”, is called a living fossil, and it has been cultivated early in human history for various...
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Identification of compounds from chufa (Eleocharis dulcis) peels with inhibitory acrylamide formation activity
Five compounds were isolated from the peels of chufa ( Eleocharis dulcis (Burm.f.) Trin. ex Hensch., Cyperaceae). The chemical structures were...
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Cytotoxic Steroids from Sonchus arvensis
A new steroid, 22Z,24R-5α,6α-epoxyergosta-8(14),22-(Z)-diene-3β,7α-diol ( 1 ), and seven known steroids were isolated from Sonchus arvensis L. The...
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Structure elucidation of small organic molecules by contemporary computational chemistry methods
Small molecules derived from natural sources such as plants, fungi, bacteria, or synthetic materials have served as promising drug candidates for a...
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Astragali Radix: comprehensive review of its botany, phytochemistry, pharmacology and clinical application
Astragali Radix ( A. Radix ) is the dried root of Astragalus membranaceus var. mongholicus (Bge) Hsiao or Astragalus membranaceus (Fisch.) Bge.,...
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Biological roles of cytochrome P450 1A1, 1A2, and 1B1 enzymes
Human cytochrome P450 enzymes (CYPs) play a critical role in various biological processes and human diseases. CYP1 family members, including CYP1A1,...
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Trichothecene and tremulane sesquiterpenes from a hallucinogenic mushroom Gymnopilus junonius and their cytotoxicity
Gymnopilus junonius (Fr.) P. D. Orton (Cortinariaceae) is a hallucinogenic mushroom, a well-known poisonous mushroom that is widely known as "big...
