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Deucravacitinib in plaque psoriasis: a profile of its use
Deucravacitinib (SOTYKTU™) is a tyrosine kinase 2 (TYK2) inhibitor that expands the availability of effective oral treatments for the management of...
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Tapinarof cream 1% in plaque psoriasis: a profile of its use
Tapinarof (VTAMA ® ) cream 1%, a topical, non-steroidal, aryl hydrocarbon receptor agonist, presents a valuable addition to the therapy options for...
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Spesolimab in generalised pustular psoriasis flares: a profile of its use
Spesolimab (Spevigo ® ) is a promising new treatment for generalised pustular psoriasis (GPP) flares. GPP is a rare and life-threatening...
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Novel Psoriasis Treatment: Development and Evaluation of a Thermo-Sensitive Pro-Penetrating Hydrogel Based on Coptis chinensis and Phellodendron amurense
Psoriasis is a chronic papulosquamous skin disease whose current treatments have severe side effects, which limits their long-term application....
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Treat psoriasis with traditional and novel topical therapies
The mainstay topical treatments for psoriasis are corticosteroids and/or vitamin D analogues, with retinoids, calcineurin inhibitors, salicylic acid...
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Several approved biologic agents are now available to treat paediatric plaque psoriasis
Off-label treatments are widely used in the treatment of paediatric psoriasis, which are prescribed on the basis of efficacy and safety data derived...
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Pruritus in psoriasis and atopic dermatitis: current treatments and new perspectives
Psoriasis and atopic dermatitis (AD) are two common chronic inflammatory skin diseases. Although showing different etiology and clinical...
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Psoriatic arthritis: the role of the nonphysician clinician in the diagnosis and treatment of patients with psoriasis
Psoriatic arthritis is a clinically heterogeneous, chronic, and progressive disease that develops in up to 30% of patients with psoriasis and is...
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Ceramides and sphingolipids are more than simple building blocks
Ceramides and sphingolipids are long chain fatty acids, which are components of the stratum corneum layer of the skin. The composition of ceramides,...
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Modulatory role of vitamins A, B3, C, D, and E on skin health, immunity, microbiome, and diseases
Disruption of the skin barrier and immunity has been associated with several skin diseases, namely atopic dermatitis (AD), psoriasis, and acne....
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Safety and Effectiveness of Multiple Switching Between Originators and Biosimilars: Literature Review and Status Report on Interchangeability
To date, numerous biosimilars are available in Europe and the practice of switching between originator and biosimilar or between two different...
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Modulation of allergic contact dermatitis via gut microbiota modified by diet, vitamins, probiotics, prebiotics, and antibiotics
Allergic contact dermatitis is one of the most common recorded occupational diseases. There are many different substances that the skin comes into...
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Dimethyl Fumarate Ameliorates the Amyotrophic Lateral Sclerosis Symptoms in Tg-SOD1G93A Mice
Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disorder that affects motor neurons and has limited therapeutic...
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Journey from Serendipity to Biologics
The world today is largely focused on biologics-based treatment for many diseases as it is a very specific way to treat any disease and also happens...
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Guselkumab in psoriatic arthritis: a profile of its use
Guselkumab (TREMFYA ® ), a fully human immunoglobulin G1λ (IgG1λ) monoclonal antibody that selectively targets interleukin (IL)-23, is an effective and...
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Determine and remove the drug trigger, usually antibiotics, that causes acute generalised exanthematous pustulosis
A wide range of drugs has been associated with the development of acute generalised exanthematous pustulosis (AGEP). Although AGEP is rare and...
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Validation of a Test System Based on Enzyme-Linked Immunosorbent Assay for the Evaluation of Etanercept Pharmacokinetics in Patients
A test system based on solid-phase ELISA was developed for the assay of etanercept patients’ in biological fluids for the purpose of evaluating the...
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mRNA level of ROCK1, RHOA, and LIMK2 as genes associated with apoptosis in evaluation of effectiveness of adalimumab treatment
BackgroundPsoriasis is a multifactorial autoimmune disease, which underlies the abnormalities of the apoptotic process. In cases of psoriasis and...
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Various Formulations of Glycyrrhizic Acid and the Possibility of Their Use in Virus-Associated and Inflammatory Diseases
Pharmaceuticals containing glycyrrhizic acid that exhibit a pleiotropic effect and reduce the risk of progression of cervical lesions associated with...
