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Leonurine Alleviates Alcoholic Steatohepatitis Through the TLR4/NF-κB Signalling Pathway
Leonurus japonicus Houtt., Lamiaceae, commonly called Chinese motherwort, has been used to treat inflammation and ulcerations. Leonurine is an...
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New Visualization Models of Designation Pathway and Group Categorization of Cell-Device and Protein-Device Combination Products in the United States
PurposeThe developer and sponsor of new cell-device and protein-device combination products in the United States needs to forecast which...
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A novel marine halophenol derivative attenuates lipopolysaccharide-induced inflammation in RAW264.7 cells via activating phosphoinositide 3-kinase/Akt pathway
Background2,4′,5′-Trihydroxyl-5,2′-dibromo diphenylmethanone (LM49), a novel active halophenol derivative synthesized by our group from marine...
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Policy developer’s perceptions on the implementation of National Health Insurance in South Africa: a qualitative study
BackgroundUniversal health coverage has gained significant momentum internationally as the policy solution to address healthcare system deficiencies...
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Elucidating the Osteogenic Potential of Naringin and Naringin–Cu(II) Complex: a Comprehensive In Vitro and In Vivo Study
This study investigates the molecular impact of naringin and naringin–Cu(II) complex on osteoblast differentiation using human osteoblastic cells and i...
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Current Prospects and Clinical Status of Microalgae Derived Chemotherapeutics
Globally, despite clinical advancements made over a decade, cancer remains a prominent cause of death. Numerous drugs have been chemically...
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Antibody-drug conjugates in cancer therapy: innovations, challenges, and future directions
The emergence of antibody-drug conjugates (ADCs) as a potential therapeutic avenue in cancer treatment has garnered significant attention. By...
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Camellia Oil Ameliorates the Intestinal Inflammation Stress in Female Drosophila melanogaster
Camellia oil, known as “Eastern olive oil,” is one of the most widely consumed edible oils in Asia and a key functional food for pregnant or...
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Evaluation of the Food and Drugs Authority, Ghana Regulatory Review Process: Challenges and Opportunities
PurposeThis study aimed to assess the current regulatory review process of the food and drugs authority (FDA) Ghana by identifying key milestones,...
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Nose
This chapter deals with preparations for nasal administration, with a local or a systemic effect. Classical nasal preparations were always associated...
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Recent advances in CRISPR technologies for genome editing
The discovery of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) system, and its development into...
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Potential Role of Herbal- and Bacterial-Derived Peptides Against Colorectal Cancer
Despite recent advances in the prevention, diagnosis, and treatment of colorectal cancer as the third cause of cancer death, the development of...
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Gastric cancer and mesenchymal stem cell-derived exosomes: from pro-tumorigenic effects to anti-cancer vehicles
Gastric cancer (GC) is one of the most prevalent malignancies in the world, with a high mortality rate in both women and men. Conventional...
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Faecal Untargeted Metabolomics Analysis Elucidates the Antihyperglycaemic Effect of Surfactin in High-Fat Diet/Streptozotocin-Induced Type 2 Diabetic Mice
Type 2 diabetes mellitus is accompanied by hyperglycaemia, liver dysfunction and intestinal dysbiosis. Bioactive peptides, as functional food,...
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AI/ML in Precision Medicine: A Look Beyond the Hype
Artificial Intelligence (AI) and Machine Learning (ML) are making headlines in medical research, especially in drug discovery, digital imaging,...
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Function and therapeutic development of exosomes for cancer therapy
Exosomes are extracellular vesicles, 50–150 nm in diameter, released by most cells. Exosomes contain several intracellular components, including DNA,...
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PLANT BIOTECHNOLOGY
Extensive research is underway worldwide on the production of active plant components from medicinal plants under controlled, reproducible conditions...
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Nanomedicine – Immune System Interactions: Limitations and Opportunities for the Treatment of Cancer
Nanoparticles interact with immune cells in many different ways. These interactions are crucially important for determining nanoparticles’ ability to...
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Technology Transfer Process
Technology transfer (TT) is a crucial step in the pharmaceutical industry to ensure that the documented knowledge, experience, and proven ability of...
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Quinoa and Chia Modulate AMPK/PPAR-ɣ Signaling in High-Fat Diet–Induced Obesity Rat Model
Obesity is one of the principal reasons behind a wide range of metabolic diseases and dramatic health complications. Recent studies shed the light on...
