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Safety of non-standard regimen of systemic steroid therapy in patients with Graves’ orbitopathy: a single-centre experience
BackgroundGraves’ orbitopathy (GO) is an autoimmune disorder of the orbit and retro-ocular tissues and the primary extrathyroidal manifestation of...
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Building a Competency Framework to Integrate Inter-disciplinary Precision Medicine Capabilities into the Medical Technology and Pharmaceutical Industry
IntroductionIntegration of precision medicine (PM) competencies across the Medical Technology and Pharmaceutical industry is critical to enable...
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Opportunities and Risks of UK Medical Device Reform
ObjectivesTo identify the potential opportunities and risks around future UK regulatory reform of medical devices.
DesignA mixed methods approach,...
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The Medical Information Scientific Process: Define, Research, Evaluate, Synthesize, and Share (DRESS)
Medical information (MI) professionals are primarily responsible for researching and responding to unsolicited requests for information on their...
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Drug poisoning in nursing homes: a retrospective study of data from the Danish Poison Information Centre
BackgroundMedication errors are common in nursing homes and may result in poisonings and hospitalizations.
ObjectiveThis study describes potential...
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Diabetes, hypertension and dyslipidemia medication prescribing in Qatari primary care settings: a retrospective analysis of electronic medical records
BackgroundGlobally, non-communicable diseases (NCDs) are recognised as a leading cause of morbidity and mortality. Medications and medicines...
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Incidence and control of steroid-induced hyperglycaemia in hospitalised patients at a tertiary care centre for lung diseases
BackgroundThe aim of this study was to determine the incidence of steroid-induced hyperglycaemia (SIH) in patients hospitalised at the tertiary...
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Principles and Considerations for Responsible Sharing of Safety Information Via the Medical Information Channel
The approach used by medical information services in answering unsolicited safety-related questions from health care professionals regarding...
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Depression in patients receiving pharmacotherapy for epilepsy: An audit in a tertiary care centre
BackgroundThe association of depression and epilepsy is thought to be bidirectional. The present study aimed to evaluate the prevalence of depression...
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Regulatory Pathways Supporting Expedited Drug Development and Approval in ICH Member Countries
Regulators and pharmaceutical companies across the world are intensifying efforts to get increasingly complex and innovative drugs to patients with...
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Systematic review for the development of a pharmaceutical and medical products prioritization framework
ObjectiveTo identify and analyze the criteria, approaches, and conceptual frameworks, used for national/international priority setting.
...
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Disaster Management and Emergency Preparedness in Low- and Middle-Income Countries
Disaster is an event that causes significant damage, destruction, and human suffering. The imbalance between needs and available resources...
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Patient Engagement and Patient Experience Data in Regulatory Review and Health Technology Assessment: A Global Landscape Review
BackgroundWorking with patients through meaningful patient engagement (PE) and incorporating patient experience data (PXD) is increasingly important...
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Intravenous human immunoglobulin utilization patterns and cost analysis in a Malaysian tertiary referral hospital
IntroductionWhile intravenous human immunoglobulin therapy is potentially lifesaving for rare diseases, the significant costs associated with its...
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Consider cannabinoids as an individual therapeutic trial in nociplastic pain
Nociplastic pain, which is characterized by widespread chronic pain and a range of central nervous system and other somatic symptoms, is associated...
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Counting the cost of public and philanthropic R&D funding: the case of olaparib
BackgroundLack of transparency around manufacturing costs, who bears the bulk of research and development costs and how total costs relate to the...
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Healthcare-associated infections in Africa: a systematic review and meta-analysis of point prevalence studies
BackgroundThere is limited data to describe the point-prevalence of healthcare-associated infections (HAIs) among patients at a regional level in...
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Adherence to metformin in adults with type 2 diabetes: a combined method approach
BackgroundMedication adherence, one of the most important aspects in the process of optimal medicines use, is unfortunately still a major challenge...
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Understanding system-focused barriers to the identification and reporting of medication errors and adverse drug events in emergency medical services
IntroductionEmergency medical services (EMS) represent an important and increasingly used entry point into the healthcare system. These services are...
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Drug-related problems and associated factors in Ethiopia: a systematic review and meta-analysis
BackgroundDrug-related problems (DRPs) can occur at any stages of medication use processes, and a single drug could be associated with multiple DRPs....
