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Many drugs are available for hypertension, with more in development
Hypertension is a global health issue that is associated with an increased risk for poor cardiovascular outcomes and kidney failure. A wide range of...
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Hypertension self-care practice and its associated factors in Bale Zone, Southeast Ethiopia: A multi-center cross-sectional study
BackgroundHypertension is a serious threat to public health globally owing to its high prevalence and related complications. It is the main risk...
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Polypill Concept in the Treatment of Arterial Hypertension (Review)
This review discusses relevant issues of antihypertensive therapy with fixed-dose combination pills (polypills). Special features of polypills are...
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Hypoxia-inducible factors and essential hypertension: narrative review of experimental and clinical data
Hypoxia-inducible factor (HIFs) is a new class of drug developed for the management of anemia in chronic kidney disease (CKD) patients. HIFs increase...
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Cannabidiol may prevent the development of congestive hepatopathy secondary to right ventricular hypertrophy associated with pulmonary hypertension in rats
BackgroundPulmonary hypertension (PH) can cause right ventricular (RV) failure and subsequent cardiohepatic syndrome referred to as congestive...
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Dapagliflozin attenuates myocardial remodeling in hypertension by activating the circadian rhythm signaling pathway
Sodium-glucose cotransporter 2 inhibitor (SGLT2i) is a new kind of antidiabetic drug which has shown beneficial effects in reducing heart...
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Using government data to understand the use and availability of medicines for hypertension and diabetes: lessons from Peru
BackgroundRegular measurement of the availability and use of key medicines for non-communicable diseases allows the tracking of progress to achieve...
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Diabetes, hypertension and dyslipidemia medication prescribing in Qatari primary care settings: a retrospective analysis of electronic medical records
BackgroundGlobally, non-communicable diseases (NCDs) are recognised as a leading cause of morbidity and mortality. Medications and medicines...
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Severe hypertension in children needs a rapid response and thorough investigation
Severe hypertension (HTN) in children requires urgent treatment. If end organ renal, neurological or cardiac damage is suspected, intravenous...
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Evaluation of management and factors associated with hypertension control in hemodialysis patients at a tertiary-care hospital in Pakistan
BackgroundHypertension is highly prevalent and poorly controlled among hemodialysis patients. However, published information regarding the management...
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Protective effect of nicotinamide and l-arginine against monocrotaline-induced pulmonary hypertension in rats: gender dependence
BackgroundThe purpose of this paper was to examine the effects of nicotinamide (ND) and l -arginine ( l -ARG) on pulmonary vascular and heart changes...
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Review of evidence on using ACEi and ARBs in patients with hypertension and COVID-19
COVID-19 has recently become a major pandemic with associated socioeconomic dimensions. Mortality statistics suggest that COVID-19 is more lethal in...
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Self-care practice among adult hypertensive patients at ambulatory clinic of tertiary teaching Hospital in Ethiopia: a cross-sectional study
BackgroundGlobally, hypertension is a major public health problem and a strong predictor of cardiovascular disease complications. To reduce and...
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Salubrious effects of ulinastatin and quercetin alone or in combination in endothelial dysfunction and vascular dementia
BackgroundVascular dementia is the second most prevalent form of dementia. Hypertension is the leading risk factor for endothelial dysfunction and...
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Over-Prescription of the Imidazoline Receptor Agonists: Evidence for Restriction of the Therapeutic Indication
BackgroundMajor antihypertensive drug classes (but not Imidazoline Receptor Agonists) have been demonstrated to reduce cardiovascular morbidity and...
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Hypertension control among euvolemic hypertensive hemodialysis patients in Malaysia: a prospective follow-up study
ObjectivesExisting literature does not provide enough information on evaluation of factors associated with pre-dialysis controlled hypertension among...
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A quantitative comparison of essential cardiovascular medicines from countries in the Southern African Development Community to the WHO model essential medicines list
BackgroundGlobally, cardiovascular disease (CVD) is a leading cause of death and disproportionately affects low- and middle-income countries (LMICs)....
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Don’t overlook monoamine oxidase inhibitors in psychiatric practice
Monoamine oxidase inhibitors (MAOIs), including phenelzine, tranylcypromine, moclobemide and selegiline are established and effective antidepressants...
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Acute coronary syndrome and its treatment outcomes in Ethiopia: a systematic review and meta-analysis
BackgroundAcute coronary syndrome (ACS) is the principal cause of death in develo** countries including Ethiopia. No study reports the overall...
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Evaluation of diclofenac utilization patterns before and after digital risk minimization intervention in outpatient settings in Montenegro
IntroductionRisk minimization measures are one of the most important tools in ensuring safe use of medicines. The evaluation of their effectiveness...