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Recent advances on Pestalotiopsis genus: chemistry, biological activities, structure–activity relationship, and biosynthesis
Strains of the fungal genus Pestalotiopsis are reported as large promising sources of structurally varied biologically active metabolites. Many...
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Recent progresses in marine microbial-derived antiviral natural products
Viruses have always been a class of pathogenic microorganisms that threaten the health and safety of human life worldwide. However, for a long time,...
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Pharmacological effects of harmine and its derivatives: a review
Harmine is isolated from the seeds of the medicinal plant, Peganum harmala L., and has been used for thousands of years in the Middle East and China....
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Recent Advances in Antiviral Benzimidazole Derivatives: A Mini Review
Benzimidazole ring system is well known for its potential for various biological activities. Recent research works have indicated the excellent...
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Phytochemistry and pharmacological activity of the genus artemisia
Artemisia and its allied species have been employed for conventional medicine in the Northern temperate regions of North America, Europe, and Asia...
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Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives
Sophora is deemed as one of the most remarkable genera of Fabaceae, and the third largest family of flowering plants. The genus Sophora comprises...
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Experimental study of antiparkinsonian action of the harmine hydrochloride original compound
BackgroundThe effects of chemical products on the nervous system have been studied by various scientists. In this work, the antiparkinsonian action...
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Anatomical characterization of ultra-structures, biominerals and histolocalization of metabolites in leaves of Genipa americana
Inserted in one of the largest families among the Angiosperms, Genipa americana L., Rubiaceae, can be found in all Brazilian territory, presenting...
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Apigenin, a novel candidate involving herb-drug interaction (HDI), interacts with organic anion transporter 1 (OAT1)
BackgroundApigenin is a flavonoid compound, widely distributed in natural plants. Various studies have suggested that apigenin has inhibitory effects...
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Antiviral effects of Phyllanthus urinaria containing corilagin against human enterovirus 71 and Coxsackievirus A16 in vitro
Human enterovirus 71 (EV71) and Coxsackievirus A16 (CA16) are major causative agents of hand, foot, and mouth disease (HFMD) especially in infants...
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Potent inhibition of Western Equine Encephalitis virus by a fraction rich in flavonoids and phenolic acids obtained from Achyrocline satureioides
Achyrocline satureioides (Lam.) DC. Asteraceae, ‘marcela del campo’, possess several pharmacological properties. Previously we reported antiviral...
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Antiviral activity of Rheum palmatum methanol extract and chrysophanol against Japanese encephalitis virus
Rheum palmatum , Chinese traditional herb, exhibits a great variety of anti-cancer and anti-viruses properties. This study rates antiviral activity of R...
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New Results on the Pharmacology and Clinical Use of the TCM-Drug Salvia miltiorrhiza
The use of Chinese herbal medicines and natural products is becoming more popular in both Chinese communities and Western societies as an alternative...
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Antiviral activity of Aloe hijazensis against some haemagglutinating viruses infection and its phytoconstituents
Evaluation of the antiviral activities of flowers, flower-peduncles, leaves, and roots of Aloe hijazensis against haemagglutinating viruses of avian...
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Acid-induced COX-2 expression and prostaglandin E2 production via activation of ERK1/2 and p38 MAPK in cultured feline esophageal smooth muscle cells
Cyclooxygenase (COX)-2 is known to play an important role in inflammatory conditions such as reflux esophagitis resulting from acid reflux. In this...
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New directions in vaccination
DNA vaccination is an important new approach to vaccination and can provide an organism with immunity against bacteria, viruses, parasites and...
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Herstellung, Prüfung und Hinweise zur Anwendung von Impfstoffen und Sera
Impfstoffe sind antigenhaltige Arzneimittel mit der Fähigkeit zur Induktion einer spezifischen aktiven Immunität. Sie sind dazu...
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Viral cysteine proteinases
Dozens of novel cysteine proteinases have been identified in positive single-stranded RNA viruses and, for the first time, in large double-stranded...