Search
Search Results
-
Knowledge and information sources of potential drug–drug interactions of healthcare professionals among Buraydah Hospitals
Background and objectiveDrug–drug interactions (DDI) are known to increase the risk of morbidity and mortality, and adversely affect the patient's...
-
Consider comorbidities, concomitant medications and organ function when treating chronic urticaria in older adults
Chronic urticaria in older adults is not well understood and specific guidelines on the diagnosis and treatment of this skin condition in older...
-
Co-Amorphous System (Paracetamol:Indomethacin): Investigations on Physical Stability and Intermolecular Interactions
To increase the performance of indomethacin (IND) by enhancing its water solubility and promoting its therapeutic efficiency, a ternary physically...
-
Don’t overlook monoamine oxidase inhibitors in psychiatric practice
Monoamine oxidase inhibitors (MAOIs), including phenelzine, tranylcypromine, moclobemide and selegiline are established and effective antidepressants...
-
The Effects of Cimetidine, N-Acetylcysteine, and Taurine on Thioridazine Metabolic Activation and Induction of Oxidative Stress in Isolated Rat Hepatocytes
Thioridazine (TZ) is used commonly in the treatment of schizophrenia. However, its clinical use has been associated with liver toxicity. Therefore,...
-
Manage seborrhoeic dermatitis in older adults with customised regimens that address age-related factors
Although seborrhoeic dermatitis can develop in people of all ages, it is especially common in older adults and severely impairs quality of life....
-
Development of a Malaysian potentially inappropriate prescribing screening tool in older adults (MALPIP): a Delphi study
IntroductionPolypharmacy and potentially inappropriate medications (PIM) are common among older adults. To guide appropriate prescribing, healthcare...
-
Protection of the hematopoietic system against radiation-induced damage: drugs, mechanisms, and developments
Sometimes, people can be exposed to moderate or high doses of radiation accidentally or through the environment. Radiation can cause great harm to...
-
Antibiotics prescribing practice among patients with urinary tract infection at outpatient department, the case of Dilchora referral hospital, Eastern Ethiopia: an institutional retrospective cross-sectional study
BackgroundInappropriate prescription of antibiotics is a global public health challenge. Widespread use, misuse, or inappropriate prescribing has...
-
Potentially inappropriate medicine use and predicting risk factors in hospitalized older adult patients: findings of a prospective observational study from Ethiopia
BackgroundOlder patients are fragile and more susceptible to medication-related problems requiring a strict assessment of their medicine list. The...
-
Managing PFAPA (periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis) in children
Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) is an uncommon, often misdiagnosed condition usually affecting...
-
Design, Synthesis, Characterization and IN VITRO Antimicrobial and Anthelmintic Evaluation of Metronidazole Derivatives Modified at Position 1
The primary aim of this study was to incorporate biologically active pharmacophores like 1,3,4-thiadiazole and Schiff base moiety into metronidazole...
-
Study on Horizon Scanning by Citation Network Analysis and Text Mining: A Focus on Drug Development Related to T Cell Immune Response
Certain innovative technologies applied to medical product development require novel evaluation approaches and/or regulations. Horizon scanning for...
-
Adherence to metformin in adults with type 2 diabetes: a combined method approach
BackgroundMedication adherence, one of the most important aspects in the process of optimal medicines use, is unfortunately still a major challenge...
-
Medication error and associated factors among adults admitted to emergency ward at the university of Gondar comprehensive specialized hospital, North-West Ethiopia: a cross-sectional study, 2022
BackgroundMedication errors are the most common cause of preventable adverse drug events at the emergency ward.
ObjectivesThis study assessed...
-
Synthesis, Analysis, and Acute Toxicity of 9-(2-diethylaminoethyl)-2-phenylimidazo[1,2-α]benzimidazole Dinitrate
The key synthetic stage (cyclization) of 9-(2-diethylaminoethyl)-2-phenylimidazo[1,2-α]benzimidazole dinitrate, which possesses antiulcer activity,...
-
Proton pump inhibitor-induced gut dysbiosis and immunomodulation: current knowledge and potential restoration by probiotics
Proton pump inhibitors (PPIs) are the most commonly prescribed drugs for the treatment of non-erosive reflux disease (NERD), ulcers associated with...
-
Detection, Monitoring, and Mitigation of Drug-Induced Nephrotoxicity: A Pragmatic Approach
The kidneys play a pivotal role in elimination of most drugs; therefore, a comprehensive understanding of renal physiology and pathology is important...
-
“Drugs to avoid” to improve quality use of medicines: how is Australia faring?
BackgroundEach year, the French independent bulletin Prescrire publishes a list of medicines, “Drugs to avoid”, that should not be used in clinical...
-
Dosage adjustment in obese children, even for common drugs, is largely unclear and a treat-to-effect approach may work best
Obesity in children, often accompanied by comorbidities, is increasingly common. For many frequently used paediatric drugs, information on dosage...