Search

Search Results

1. Glycosylated Flavonoids Have Fewer Antibacterial Activity than Corresponding Aglycone: Is It True for Antivirulence Activity?

   Flavonoids are an important class of natural compounds with a broad spectrum of biological activities, which makes them interesting candidates for...

   Thayná F. Barros, Júlia S. Borges, ... Danielle S. Trentin in Revista Brasileira de Farmacognosia

   Article 21 May 2024
   

2. New Direction in the Determination of Bacterial Endotoxins: Analysis Using Recombinant Factor C

   A comparative study of methods for the determination of bacterial endotoxins using recombinant reagents confirmed that the analytical results did not...

   O. V. Shapovalova, N. P. Neugodova, ... E. O. Stepanyuk in Pharmaceutical Chemistry Journal

   Article 11 November 2022
   

3. Potential Directions in the Use of Graphene Nanomaterials in Pharmacology and Biomedicine (Review)

   This article provides a brief review of the current scientific literature on the structure, properties, and preparation of graphene nanomaterials...

   I. I. Kulakova, G. V. Lisichkin in Pharmaceutical Chemistry Journal

   Article 30 March 2022
   

4. Should community pharmacies provide COVID-19 screening services?

   Ching Siang Tan in Drugs & Therapy Perspectives

   Article 14 August 2020

5. Evaluation of Biological Activities and Enzyme Inhibitory Potential of 7,8-Dihydroxy-3-(4-methylphenyl) Coumarin

   In this study, antioxidant, antibacterial, cytotoxic, and antioxidant enzyme inhibitory properties of the 7,8-dihydroxy-3-(4-methylphenyl) coumarin...

   Gökhan Sadi, Hacer Bora, ... İbrahim Yılmaz in Revista Brasileira de Farmacognosia

   Article 24 August 2022
   

6. Horizon Scanning in Tissue Engineering Using Citation Network Analysis

   Background

   Establishing a horizon scanning method is critical for identifying technologies that require new guidelines or regulations. We studied the...

   Kouhei Otsuka, Takuya Takata, ... Mayumi Shikano in Therapeutic Innovation & Regulatory Science

   Article Open access 18 May 2023
   

7. Hypoglycemic Activity of Glycyrrhizic Acid and Some of its Derivatives in the Alloxan Diabetes Model in Rats

   The hypoglycemic activity of glycyrrhizic acid (GA, I ), its trisodium ( II ) and sodium-dilithium salts ( III ), and a conjugate with L -methionine methyl...

   L. A. Baltina, T. A. Sapozhnikova, ... R. M. Kondratenko in Pharmaceutical Chemistry Journal

   Article 22 July 2021
   

8. Methylation of Quercetin by Diazomethane and Hypoglycemic Activity of its Tetra-O-Methyl Ether

   The tetra- O -methyl ether of quercetin (QU) 3 (54%), 3,7,4′-tri- O -methyl ether 4 (30%), and a previously unreported 3,7,3-tri- O -methyl ether of QU 5 ...

   E. R. Karimova, L. A. Baltina, ... N. S. Makara in Chemistry of Natural Compounds

   Article 12 September 2020
   

9. Gold Nanoparticles: Synthesis, Functionalization and Biomedical Applications Especially in Cardiovascular Therapy

   Global burden of cardiovascular diseases (CVDs) is one of the main and leading causes of death around the world. Atherosclerosis early detection...

   Adli A. Selim, Tamer M. Sakr, Basma M. Essa in Pharmaceutical Chemistry Journal

   Article 15 April 2023
   

10. Structures, biomimetic synthesis, and anti-SARS-CoV-2 activity of two pairs of enantiomeric phenylpropanoid-conjugated protoberberine alkaloids from the rhizomes of Corydalis decumbens

    (±)-Decumicorine A ( 1 ) and (±)- epi -decumicorine A ( 2 ), two pairs of enantiomeric isoquinoline alkaloids featuring a novel phenylpropanoid-conjugated...

    **g-Guang Lu, Yingwei Wang, ... Zhi-Hong Jiang in Archives of Pharmacal Research

    Article 19 September 2022
    

11. Quenching Studies as Important Toolkit for Exploring Binding Propensity of Metal Complexes with Serum Albumin and DNA (A Review)

    Coordination complexes have played an important role in medicine since ancient times; recently their pharmacological activity has been the subject of...

    Anju Saini, Priti Bansal in Pharmaceutical Chemistry Journal

    Article 11 July 2022
    

12. UPLC-Q-Orbitrap HRMS Analysis of Coptis chinensis Aerial Parts and Its Regulatory Activity on Glucose-lipid Metabolism

    Coptis chinensis Franch., Ranunculaceae, is a widely used herbal medicine in Asian countries. It exhibits many important pharmacological effects. The...

    Guanhua Lou, Haijun **ong, ... Qinwan Huang in Revista Brasileira de Farmacognosia

    Article 10 February 2021
    

13. Water-Soluble Anionic C₆₀-Fullerene Derivatives as Antidotes for HG(II) Ions in Tests on Escherichia Coli Cells

    Three water-soluble C ₆₀ -fullerene derivatives functionalized by anionic adducts of various chemical compositions and structures were prepared in...

    A. V. Zhilenkov, E. A. Khakina, ... D. G. Deryabin in Pharmaceutical Chemistry Journal

    Article 11 July 2019
    

14. The pivotal role of pituitary adenylate cyclase-activating polypeptide for lactate production and secretion in astrocytes during fear memory

    Background

    Pituitary adenylate cyclase-activating polypeptide (PACAP) plays an essential role in the modulation of astrocyte functions. Although...

    Yuki Kambe, Yu Yamauchi, ... Atsuro Miyata in Pharmacological Reports

    Article 09 April 2021
    

15. Antioxidant activity evaluation of dried herbal extracts: an electroanalytical approach

    The prevention of chronic and degenerative diseases, is a health concern deeply associated with oxidative stress. Such progressive phenomena can be...

    Karla Carneiro Siqueira de Leite, Luane Ferreira Garcia, ... Eric Souza de Gil in Revista Brasileira de Farmacognosia

    Article Open access 03 May 2018

16. Choosing a Mobile Sensor Technology for a Clinical Trial: Statistical Considerations, Developments and Learnings

    The DIA Study Endpoints Community Working Group on Mobile Sensor Technology (MST) series addresses considerations that may be useful for selecting...

    Colleen Russell, Marie McCarthy, ... Susan Wong in Therapeutic Innovation & Regulatory Science

    Article 18 June 2020
    

17. Biomedical Applications of Silver Nanoclusters (Review)

    This review summarizes fragmentary data on the chemical characteristics of silver atoms in nanoclusters and nanoparticles and shows successful...

    V. P. Pchelkin in Pharmaceutical Chemistry Journal

    Article 15 June 2020
    

18. Synthesis and Inhibitory Properties of Imines Containing Monoterpenoid and Adamantane Fragments Against DNA Repair Enzyme Tyrosyl-DNA Phosphodiesterase 1 (Tdp1)

    Six imines including four new ones were synthesized via the reaction of monoterpenoid aldehydes with aminoadamantanes. The inhibitory activities of...

    A. L. Zakharenko, E. S. Mozhaitsev, ... O. I. Lavrik in Chemistry of Natural Compounds

    Article 25 July 2018
    

19. Nrf2 in liver toxicology

    Liver plays essential roles in the metabolism of many endogenous chemicals and exogenous toxicants. Mechanistic studies in liver have been at the...

    Keiko Taguchi, Thomas W. Kensler in Archives of Pharmacal Research

    Article 28 November 2019
    

20. Biophysical Considerations for Development of Antibody-Based Therapeutics

    Development of therapeutic monoclonal antibodies requires rigorous measurements of the kinetic and thermodynamic binding properties of...

    Andrew W. Drake, Yasmina N. Abdiche, Giuseppe A. Papalia in Development of Antibody-Based Therapeutics

    Chapter 2018