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Effects of carvedilol on human prostate tissue contractility and stromal cell growth pointing to potential clinical implications
BackgroundApart from antagonizing ß-adrenoceptors, carvedilol antagonizes vascular α 1 -adrenoceptors and activates G protein-independent signaling....
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Inhibitory effects of 6′-sialyllactose on angiotensin II-induced proliferation, migration, and osteogenic switching in vascular smooth muscle cells
Excessive production and migration of vascular smooth muscle cells (VSMCs) are associated with vascular remodeling that causes vascular diseases,...
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Nutritional and biological evaluation of Phoenix canariensis pollen grains
The nutritional value of pollens of Phoenix canariensis Chabaud, Arecaceae, was evaluated. HPLC analysis of vitamins revealed the predominant...
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DISCUSSION OF HERBAL DRUGS BASED ON THE BIOGENETIC CLASSIFICATION OF THEIR MAIN ACTIVE COMPONENTS
Honey is prepared by honey-bees (Apis mellifera) from the nectar and honeydew of flowers. After chemical conversion by the gastric juices in the... -
BIOLOGICAL ACTIVITY OF COMPOUNDS OF PLANT ORIGIN
Due to their structural diversity and specific biological effects, natural substances play an important role in medication. Many of the medicines... -
Trifolium pratense: Friable calli, cell culture protocol and isoflavones content in wild plants, in vitro and cell cultures analyzed by UPLC
Trifolium pratense L., Fabaceae, is a rich source of isoflavones and has become the focus of several studies related to its phytoestrogenic activity....
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Pterodon pubescens oil nanoemulsions: physiochemical and microbiological characterization and in vivo anti-inflammatory efficacy studies
Pterodon pubescens (Benth.) Benth., Fabaceae, fruits have been investigated for their anti-inflammatory and antinociceptive activities, and have...
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Evaluation of the clinical indications, adverse drug reactions, and finasteride use in patients with benign prostatic hyperplasia in Poland
BackgroundBenign prostatic hyperplasia (LUTS/BPH) is one of the most common urinary disorders in elderly men. The symptoms of the disease include...
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Switching statin-treated patients from fenofibrate to the prescription omega-3 therapy icosapent ethyl: a retrospective case series
IntroductionPatients receiving statin therapy for dyslipidaemia often require treatment with an additional agent to control triglyceride levels....
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Human Cytochrome P450 Enzymes
The cytochrome P450 (P450) enzymes first attracted interest because of their relevance to the metabolism of drugs, steroids, and carcinogens.... -
Pharmacodynamic Modeling
The pharmacodynamics of anti-cancer agents, as opposed to direct acting medications, pose a unique set of challenges. These challenges include;... -
Pharmocoepigenetics: a new approach to predicting individual drug responses and targeting new drugs
Epigenetics is the study of heritable changes in genes and gene expression that do not involve DNAnucleotide sequences. Epigenetic modifications...
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Urologika
Urologika werden zur Behandlung von Miktionsstörungen im weitesten Sinne angewandt, denen Erkrankungen der Prostata und der Blase sowie verschiedene... -
Urologika
Wie seit Jahren stellen die Prostatamittel mit knapp 65% der Verordnungen die überwiegende Gruppe der Urologika dar. Danach folgen die urologischen... -
Urologika
Wie seit Jahren stellen die Prostatamittel mit über zwei Drittel der Verordnungen die überwiegende Gruppe der Urologika dar. Danach folgen die... -
Urologika
Mit fast 70 Prozent der Verordnungen stellen die Prostatamittel nach wie vor die überwiegende Gruppe der Urologika dar. Urologische Antiinfektiva,... -
Effective Risk Management Tools
Risk management proactively assesses the potential risks and benefits of health care interventions, including both drugs and medical devices. Risk...
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Electronic Diaries: Exploring Cross-Cultural Preferences and Acceptability
IntroductionThe literature supports the use of electronic diaries (e-diaries) in a variety of populations, including different disease and age...