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Therapeutic Antidiabetic and Antioxidative Synergism of Zn(II)-Syringic Acid Complexation
Zinc(II) and syringic acid are natural supplements with medicinal attributes. The antidiabetic and antioxidative synergism between zinc(II) and...
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Synthesis, In Silico Analysis, Antibacterial, Radical Scavenging and Antidiabetic Activities of Certain Bis-Azetidinones and Bis-Thiazolidinones
A panel of 1,1-(phenylene)bis[3-chloro-4-(substituted phenyl)azetidin-2-ones] ( 4a-m ) and 3,3′-(1,4-phenylene)bis[2-(substituted...
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Potential of UK and US newspapers for sha** patients' knowledge and perceptions about antidiabetic medicines: a content analysis
BackgroundInformation about how newspapers portray antidiabetic medicines to readers is lacking. This study investigated the reporting on...
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Seasonal Chemical Variation and Antidiabetic Activity of Major Compounds in Artemisia afra Infusions
Artemisia afra Jacq. ex Willd., Asteraceae, is a very popular herbal medicine in Southern Africa and is mainly used in the form of a tea infusion for...
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Antidiabetic Effect of Garlic
Diabetes affects a substantial part of the world’s population and, possibly, is the world’s fastest-growing metabolic disease. Garlic, Allium sativum ...
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Antidiabetic Activity and Hepatotoxic Effect of Aqueous Extracts of Struthanthus quercicola
Struthanthus quercicola (Schltdl. & Cham.) D.Don, Loranthaceae, is the true Mexican mistletoe has been used by traditional healers for the treatment...
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What is the role of pioglitazone for patients with type 2 diabetes in value-based care settings?
Type 2 diabetes is a significant burden on the healthcare system with unique challenges in the value-based payment system. Although there are a...
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Anti-diabetic Effect of Major Compounds from Commelina diffusa
Although Commelina diffusa Burm.f., Commelinaceae, has been proven to exhibit many pharmacological activities, the scientific evidence for its...
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Cinnamic Acid Improves Glucose Uptake and Utilization with Concomitant Improvement of Redox and Bioenergetic Homeostasis, While Modulating Glucose-Lipid Metabolic Switch in Isolated Psoas Muscle
The antidiabetic properties of cinnamic acid was investigated in isolated psoas muscles from Sprague Dawley male rats, by studying its ability to...
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Uracil Hydroxybenzamides as Potential Antidiabetic Prodrugs
A series of N 1 , N 3 - bis -hydroxybenzoyl, -acetoxybenzoyl, and -methoxybenzoyl uracil derivatives were synthesized. All compounds were screened for the...
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Phytochemical and pharmacological properties of the genus Tamarix: a comprehensive review
The genus Tamarix in the Tamaricaceae family consists of more than 100 species of halophyte plants worldwide that are mainly used to improve...
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Therapeutic Potential of Pyrazole Containing Compounds: an Updated Review
Among a large number of nitrogen-containing heterocyclic compounds, pyrazole is a privileged scaffold with the molecular formula C 3 H 3 N 2 H. It consists...
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Effect of a Low-Molecular-Weight NGF Mimetic on a Combined High-Carbohydrate Diet/Streptozotocin-Induced Model of Type 2 Diabetes
Results of the antidiabetic activity of the low-molecular-weight NGF mimetic GK-2 [bis-( N -monosuccinylglutamyl- L -lysine) hexamethylenediamide] in a...
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Recent Advances in the Pharmacological Properties and Molecular Mechanisms of Carvacrol
Plant secondary metabolites have received a lot of attention for their immense pharmacological activities and low side effects. Monoterpenes,...
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Flavonoids from the Leaves of Chromolaena odorata and Their α-Glucosidase Inhibitory Activity
The leaf water extracts of C. odorata are used as an antidiabetic herbal drug in traditional medicine. The aim of this study was to determine...
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Synthesis and Investigation of Antidiabetic Response of New Coumarin Derivatives Against Streptozotocin Induced Diabetes in Experimental Rats
A new series of coumarin analogs ( 1a – 1g ) were designed and synthesized. The chemical structures of all compounds were elucidated by IR, 1 H NMR, 13 C...
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Comparative Plant Metabolomics of Momordica charantia Seeds and Fruits
Momordica charantia L., Cucurbitaceae, known mainly as karela, bitter gourd or bitter melon, and balsam pear, is used for antihyperglycemic,...
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Low Molecular Weight NGF Mimetic Enhances the Overall Plasma Antioxidant Capacity in Rats with Streptozotocin-Induced Diabetes
Results from studies of the antidiabetic and antihyperglycemic activity of a low-molecular-weight NGF mimetic, compound GR-2 [bis-( N -monosuccinyl- L -glutamyl-...
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Could nutrient supplements provide additional glycemic control in diabetes management? A systematic review and meta-analysis of randomized controlled trials of as an add-on nutritional supplementation therapy
This systematic review and meta-analysis assessed the antidiabetic effect of pharmaconutrients as an add-on in type 2 diabetes mellitus patients by...
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Physicochemical Properties and Methods for the Determination of Metformin Hydrochloride (A Review)
Metformin hydrochloride is widely used to treat diabetes mellitus. This review presents its physical and chemical properties and discusses methods of...