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Can probiotics be used in the prevention and treatment of bronchial asthma?
Asthma is a lifelong condition with varying degrees of severity and susceptibility to symptom control. Recent studies have examined the effects of...
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The Prophylactic Effects of Isosteviol Aerosol Inhalation on Bronchial Asthma in Mice
The diterpenoid isosteviol is one of the stevia derivatives that have reported various activities . In mice inhaling isosteviol, OVA- and ACh-induced...
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Diosmetin Alleviates Ovalbumin-Induced Nasal Inflammation by Regulating the SIRT1/NF-κB Signaling in Mouse Models of Allergic Rhinitis
Diosmetin is a flavonoid compound with various pharmacological activities, which plays a vital role in alleviating the development of asthma and...
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A multidisciplinary approach to verify and de-label of drug allergic histories in a university hospital in Thailand: a retrospective descriptive study
BackgroundMislabeling of drug allergic histories causes avoidable negative impacts on patients and healthcare system. Although multidisciplinary...
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Anti-asthmatic Substances in the Chinese Herbal Formulation Huagai San Based on In Vitro and In Vivo Analysis and Network Pharmacology
“Huagai san,” a Chinese classical herbal formulation, has been used for nearly 50 years to treat various conditions including bronchial asthma owing...
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FNF-12, a novel benzylidene-chromanone derivative, attenuates inflammatory response in in vitro and in vivo asthma models mediated by M2-related Th2 cytokines via MAPK and NF-kB signaling
Background and aimThis study evaluates a novel benzylidene-chromanone derivative, FNF-12, for efficacy in in vitro and in vivo asthma models.
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Medicinal and Therapeutic Properties of Ephedra
Ephedra is one of the oldest medicinal plants in traditional Chinese medicine for nearly 5000 years. The medicinal species are used as a stimulant...
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The effects of BRL-50481 on ovalbumin-induced asthmatic lung inflammation exacerbated by co-exposure to Asian sand dust in the murine model
Asian sand dust (ASD), which mainly originates in China and Mongolia in the spring and blows into Korea, can exacerbate respiratory and immunological...
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New Therapeutic Options in Pulmonal Diseases: Sphingolipids and Modulation of Sphingolipid Metabolism
Sphingolipids are crucial molecules in the respiratory airways. As in most other tissues and organs, in the lung sphingolipids play an essential role...
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Inhibitory effects of sildenafil and tadalafil on inflammation, oxidative stress and nitrosative stress in animal model of bronchial asthma
BackgroundCyclic neucleotides are involved in many cellular functions including smooth muscle relaxation, inflammation, and signal transduction....
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Long noncoding RNA atlas of the inflammation caused by asthma in mice
There is little evidence regarding the roles of long noncoding RNAs (lncRNAs) in inflammation caused by asthma. In this study, we successfully...
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Inhibitory effects of orientin in mast cell-mediated allergic inflammation
BackgroundMast cells are immune effector cells mediating allergic inflammation by the secretion of inflammatory mediators such as histamine and...
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Methodological Approaches to Improving the Quality of Medicinal Plant Raw Materials of the Pollen Morphology Group
Allergen-specific immunotherapy (ASIT) is a method of treating allergic diseases with an IgE-mediated mechanism of development. ASIT is effective in...
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Targeted Molecular Therapeutics for Pulmonary Diseases: Addressing the Need for Precise Drug Delivery
Respiratory diseases are a major concern in public health, impacting a large population worldwide. Despite the availability of therapies that...
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Different effects of acetyl-CoA carboxylase inhibitor TOFA on airway inflammation and airway resistance in a mice model of asthma
Background and objectiveAcetyl CoA carboxylase (ACC) regulates the differentiation of Th1, Th2, Th17 cells and Treg cells, which play a critical role...
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Mediators of the homeostasis and effector functions of memory Th2 cells as novel drug targets in intractable chronic allergic diseases
Allergic patients have life-long chronic inflammatory diseases with repeated relapses and exacerbations. Currently used allergy therapeutics have...
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HPTLC Method Development for Estimation of Vasicine in Herbal Extract and its Marketed Formulations
Adhatoda vasica Nees, is locally known as adulsa, which is used in various medicinal activities. Hence, an objective of the study was to develop an...
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Clinical Efficacy of Long-Acting β2 Agonists and Long-Acting Muscarinic Antagonist for Moderate to Severe Chronic Obstructive Pulmonary Disease
We have studied the clinical efficacy of long-acting β2-agonist (LABA) and long-acting muscarinic antagonist (LAMA) for the treatment of moderate to...
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Cimifugin Mechanism of Action from Saposhnikovia divaricata in the Treatment of Atopic Dermatitis
The present study aimed to explore the mechanism of action of cimifugin, the primary active ingredient in Saposhnikovia divaricata (Turcz.)...
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Nasal sprays for treating COVID-19: a scientific note
Clinical management of COVID-19 has been a daunting task. Due to the lack of specific treatment, vaccines have been regarded as the first line of...
