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Anti-inflammatory Activity of Total Alkaloids in Nelumbo nucifera and Simultaneous Determination of Major Bisbenzylisoquinolines
Plumula nelumbinis , the green embryo of the mature seeds of Nelumbo nucifera Gaertn., Nelumbonaceae, is widely used in traditional Chinese medicine...
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Identification and Evaluation of Free Radical Scavenging Activity of Quinolizidine Alkaloids Isolated from Various Parts of Anagyris foetida Plant
Anagyris foetida is a genus of legumes belonging to the Fabaceae family, considered as a good source of medications to treat various ailments. In...
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Ameliorative Effects of Alkaloids from Narcissus cv. Hawera: Behavioral Changes Following Acute and Accelerated Chronic Restraint Stress
The adverse effects of stress explain the increased demand for phytochemical and biochemical pharmacological agents with potential adaptogenic...
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Purification of Alkaloids by Countercurrent Chromatography
Alkaloids are nitrogen-containing compounds of the secondary metabolism of plants and microorganisms, which can also be found in animals, insects,...
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Alkaloids of Gnaphalium polycaulon with Anti-Alzheimer’s Activity
Three alkaloids were isolated from the aerial parts of Gnaphalium polycaulon Pers., Asteraceae, collected from San Juan Huancollo, Ingavi Province,...
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Hyperoside attenuates pyrrolizidine alkaloids-induced liver injury by ameliorating TFEB-mediated mitochondrial dysfunction
Pyrrolizidine alkaloids (PAs) are potent hepatotoxins that can cause liver damage. Hyperoside (Hyp), a natural flavonoid, can be extracted from...
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Structures, biomimetic synthesis, and anti-SARS-CoV-2 activity of two pairs of enantiomeric phenylpropanoid-conjugated protoberberine alkaloids from the rhizomes of Corydalis decumbens
(±)-Decumicorine A ( 1 ) and (±)- epi -decumicorine A ( 2 ), two pairs of enantiomeric isoquinoline alkaloids featuring a novel phenylpropanoid-conjugated...
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In vitro antiviral activity of piperidine alkaloids from Senna spectabilis flowers on Chikungunya virus infection
BackgroundChikungunya fever is an endemic disease caused by the Chikungunya virus (CHIKV). To date there is no antiviral treatment against this...
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Structural Diversity and Biological Potential of Alkaloids from the Genus Hippeastrum, Amaryllidaceae: an Update
The subfamily Amaryllidoideae, Amaryllidaceae, presents an exclusive group of structures known as Amaryllidaceae alkaloids, which have a broad...
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Pharmacokinetics and Oral Bioavailability of Coumarins and Carbazole Alkaloids from Clausena harmandiana Root Bark in Rats
The root bark of Clausena harmandiana Pierre ex Guillaumin, Rutaceae, has been widely studied for its antimalarial activity, action against cancer...
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Alkaloids from the Leaves of Annona crassiflora and Their Cytotoxic Activity
Aporphines are a class of alkaloids mostly reported in Magnoliids. The genus Annona , Annonaceae, presents great structural diversity of these...
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Acetylcholinesterase Inhibitory Alkaloids from the Flowers and Seeds of Erythrina caffra
Chemical investigation of flower and seed extracts of Erythrina caffra Thunb., Fabaceae, resulted in the isolation of an undescribed alkaloid,...
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Indole Alkaloids from Vinca erecta, Structure and Stereochemistry
Stereochemical and structural aspects of series of indoline, α-methyleneindoline, indolenine, indole, and 2-oxoindoline alkaloids. The...
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Plumeran Indole Alkaloids From Aspidosperma pyrifolium Flowers
Aspidosperma pyrifolium Mart., Apocynaceae, is a species popularly known with the popular Brazilian names of “pereiro” and “pau-pereiro.” It is a...
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Bioactive Alkaloids from Whole Plants of Thalictrum cultratum
Two new tricyclic alkaloids ( 1 and 2 ), together with three known ( 3 – 5 ) alkaloids, were isolated from the whole plants of Thalictrum cultratum . Their...
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Diterpenoid Alkaloids from the Roots of Aconitum iochanicum
Three new diterpenoid alkaloids, namely 1- N -deethyl-1,16-demethoxy-1,16-dihydroxy- N (19)-enaustroconitine A ( 1 ), 1- N -deethyl-1,16-demethoxy-1,16-dihydroxy-18-methoxy-...
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Comparative Study of the Quantitative Determination of Lappaconitine in Aconitum septentrionale by High-Performance Liquid Chromatography and Spectrophotometry
Methods for quantification of total alkaloids in terms of lappaconitine in Aconitum septentrionale Koelle, a plant raw material that is the main...
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Isoquinoline Alkaloids from Whole Plants of Thalictrum cirrhosum and Their Antirotavirus Activity
Two new ( 1 and 2 ), together with two known ( 3 and 4 ), isoquinoline alkaloids were isolated from the whole plants of Thalictrum cirrhosum . Their...
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Anti-inflammatory Response and Detection of Pharmacologically Active Components in Serum of Rats with Carrageenan-Induced Paw Swelling Treated with Phellodendron chinense
Phellodendron chinense C.K.Schneid., Rutaceae, is a traditional Chinese medicine that is considered to have heat-clearing and detoxifying actions and...