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New Direction in the Determination of Bacterial Endotoxins: Analysis Using Recombinant Factor C
A comparative study of methods for the determination of bacterial endotoxins using recombinant reagents confirmed that the analytical results did not...
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Ortho-vanillin nanoparticle-doped glucan microspheres exacerbate the anti-arthritic effects of methotrexate in adjuvant-induced arthritis in rats
BackgroundMethotrexate (MTX) commonly used in rheumatoid arthritis (RA) has severe adverse effects. Ortho-vanillin, an inhibitor of Toll-like...
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Cytotoxic Effects and Antitumor Activity of Polysaccharides Isolated from the Fruiting Body of Ganoderma lucidum Basidial Mushroom
The work was devoted to the isolation of polysaccharides from Ganoderma lucidum basidiomycete raw material collected in Uzbekistan and the study of...
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Glycolytic metabolism supports microglia training during age-related neurodegeneration
Glucose is a major energy source for the brain, necessary to preserve proper neurophysiological functions; aberrant glucose metabolism in the brain...
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Physicochemical Characterization and Biological Evaluation of Agaricus subrufescens Polysaccharides in Human Blood Cells
The present work aimed to isolate and characterize the polysaccharides from Agaricus subrufescens Peck (1893), Agaricaceae, and subsequently evaluate...
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Astragalus polysaccharide: a review of its immunomodulatory effect
The Astragalus polysaccharide is an important bioactive component derived from the dry root of Astragalus membranaceus . This review aims to provide a...
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Secondary fungal infections in SARS-CoV-2 patients: pathological whereabouts, cautionary measures, and steadfast treatments
The earliest documented COVID-19 case caused by the SARS-CoV-2 coronavirus occurred in Wuhan, China, in December 2019. Since then, several SARS-CoV-2...
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Chemical Constituents of Date Palm (Phoenix dactylifera L.) Fruit-Free Bunches and Their Biological Activities
Phytochemical investigation of Phoenix dactylifera L. (date palm) fruit-free bunches lead to the isolation of seven compounds, including new...
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Oteseconazole in recurrent vulvovaginal candidiasis: a profile of its use
Oteseconazole (Vivjoa ® ), an orally administered azole antifungal, is a valuable, efficacious, and well tolerated treatment option for reducing the...
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Obtaining Chitosan from Artemia Cysts and Studying its Sorption Properties
Chitosan was isolated from Artemia cysts growing in the Aral Sea. The identity of the obtained chitosan and a reference sample was confirmed by IR...
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Consider old and new approaches when treating dyslipidaemia
Statins are still the cornerstone of lipid-lowering therapy, whether it is to decrease low-density lipoprotein-cholesterol (LDL-C) or triglycerides...
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Isolation of Polysaccharides from Horse Chestnut (Aesculus hippocastanum L.) Shells and their Acute Toxicity and Influence on the Immune System
The acute toxicity and influence on the immune system of the melanin–polysaccharide complex and β-glucans isolated from horse chestnut shells ( Aesculu...
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Current Prospects and Clinical Status of Microalgae Derived Chemotherapeutics
Globally, despite clinical advancements made over a decade, cancer remains a prominent cause of death. Numerous drugs have been chemically...
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Medicinal Plants in Peru as a Source of Immunomodulatory Drugs Potentially Useful Against COVID-19
The current COVID-19 pandemic, characterized by a highly contagious severe acute respiratory syndrome, led us to look for medicinal plants as an...
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Phytochemical Screening, Free-Radical Scavenging Activity, in vitro Alpha-Amylase Inhibitory Activity, and in vivo Hypoglycemic Activity Studies of Several Crude Drug Formulations Based on Selected Medicinal Plants of Nepal
Diabetes mellitus (DM) is a chronic metabolic disorder leading toward elevation of the blood glucose level due to insulin insufficiency (Type I) or...
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Anti-dengue Potential of Mangiferin: Intricate Network of Dengue to Human Genes
Dengue fever has become one of the deadliest infectious diseases and requires the development of effective antiviral therapies. It is caused by...
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Astragali Radix: comprehensive review of its botany, phytochemistry, pharmacology and clinical application
Astragali Radix ( A. Radix ) is the dried root of Astragalus membranaceus var. mongholicus (Bge) Hsiao or Astragalus membranaceus (Fisch.) Bge.,...
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Dietary schizophyllan reduces mitochondrial damage by activating SIRT3 in mice
Schizophyllan (SPG), produced by Schizophyllum commune , is an exopolysaccharide with multiple academic and commercial uses, including in the food...
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Antidiabetic Effect of Garlic
Diabetes affects a substantial part of the world’s population and, possibly, is the world’s fastest-growing metabolic disease. Garlic, Allium sativum ...
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Alcoholic liver disease: a new insight into the pathogenesis of liver disease
Excessive alcohol consumption contributes to a broad clinical spectrum of liver diseases, from simple steatosis to end-stage hepatocellular...
