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Showing 61-80 of 1,495 results
  1. Pharmacological Aspects of the Use of Lipoic Acid (Review)

    Lipoic (thioctic) acid (LA) [ R -5-(1,2-dithiolan-3-yl)pentanoic acid] is a natural compound that enters the human body with food. LA is used to treat...

    A. M. Usacheva, A. V. Chernikov, ... V. I. Bruskov in Pharmaceutical Chemistry Journal
    Article 12 February 2022
  2. Scope and challenges of nanoparticle-based mRNA delivery in cancer treatment

    Messenger RNA (mRNA) recently emerged as an appealing alternative to treat and prevent diseases ranging from cancer and Alzheimer’s disease to...

    Md. Emranul Karim, Sheikh Tanzina Haque, ... Ezharul Hoque Chowdhury in Archives of Pharmacal Research
    Article 24 November 2022
  3. Scaffolds of Purine Privilege for Biological Cytotoxic Targets: A Review

    The primary aim of this review is to emphasize and guide the biological cytotoxic activities of purine scaffold, also with a focus on emerging purine...

    Srimanta Kumar Das, Biswaranjan Behera, Chandra Shekhar Purohit in Pharmaceutical Chemistry Journal
    Article 01 September 2023
  4. Detonation Nanodiamonds as Promising Drug Carriers

    Information on the use of detonation nanodiamonds (DNDs) in biomedical applications is reviewed. Literature data and our own results on the...

    R. Yu. Yakovlev, P. G. Mingalev, ... G. V. Lisichkin in Pharmaceutical Chemistry Journal
    Article 20 July 2020
  5. Parenteral

    This chapter gives an overview of parenteral dosage forms and the rationale for their use. Parenterals are sterile preparations that are injected...
    Marija Tubic-Grozdanis, Irene Krämer in Practical Pharmaceutics
    Chapter 2023
  6. Eczematous drug eruptions mostly manageable with emollients and corticosteroids

    Eczematous drug eruptions (EDEs) constitute up to 10% of cutaneous drug reactions, with biologics and some newer cancer treatments and antivirals...

    Caroline Fenton, Connie Kang in Drugs & Therapy Perspectives
    Article 06 December 2021
  7. Linzagolix in moderate to severe symptoms of uterine fibroids: a profile of its use

    Linzagolix (Yselty ® ) is an orally administered gonadotropin-releasing hormone receptor antagonist approved in the EU for the treatment of moderate to...

    Simon Fung, Hannah A. Blair in Drugs & Therapy Perspectives
    Article 22 August 2023
  8. Chemotherapy-induced peripheral neuropathy—part 2: focus on the prevention of oxaliplatin-induced neurotoxicity

    Background

    Chemotherapy-induced peripheral neuropathy (CIPN) is regarded as one of the most common dose-limiting adverse effects of several...

    Kinga Sałat in Pharmacological Reports
    Article Open access 28 April 2020
  9. Classification of Companion Diagnostics: A New Framework for Biomarker-Driven Patient Selection

    Background

    Modern personalized medicine strategies builds on therapy companion diagnostics to stratify patients into subgroups with differential...

    Cynthia Huber, Tim Friede, ... Norbert Benda in Therapeutic Innovation & Regulatory Science
    Article Open access 28 November 2021
  10. Pharmacological Strategies to Overcome Tumor Resistance to Anticancer Hormonal, Targeted, and Immunotherapy

    Possible molecular mechanisms of develo** tumor drug resistance to anticancer hormonal, targeted, and immunotherapy that are associated with the...

    T. A. Fedotcheva, N. L. Shimanovsky in Pharmaceutical Chemistry Journal
    Article 25 May 2023
  11. Biopharmaceutics

    Biopharmaceutics, in connection with pharmacokinetics, is the field that investigates and describes everything that happens with a medicinal product...
    Henderik Frijlink, Frederic Lagarce, ... Herman Woerdenbag in Practical Pharmaceutics
    Chapter 2023
  12. Cytotoxic Activity of Pimpinella isaurica and In Silico Analysis of Flavonoids

    Pimpinella L., Apiaceae, is one of the largest genera and has a broad spectrum of biological or pharmacological activities including...

    Kevser Taban Akça, Esra Emerce, ... Ipek Süntar in Revista Brasileira de Farmacognosia
    Article 06 August 2022
  13. Identification of Confusing Medicine Proprietary Names: Toward Safe Medicine Use—A Cross-Sectional Study in Sri Lanka

    Background

    Look-alike sound-alike (LASA) medications have similar pronunciation (phonetic) and/or manifestation (orthographic), which could create...

    Manori Jayasinghe, Thotawaththage Loshadhi Indunika Srilal, ... Shukry Zawahir in Therapeutic Innovation & Regulatory Science
    Article 17 August 2023
  14. Budget impact analysis of breast cancer medications: a systematic review

    Background

    Breast cancer (BC) is the most common cancer globally among women, with 2,261,419 new cases in 2020; systemic treatment may be...

    Ghader Mohammadnezhad, Melika Sattarpour, Najmeh Moradi in Journal of Pharmaceutical Policy and Practice
    Article Open access 29 December 2022
  15. Trends in Canadian prescription drug purchasing: 2001–2020

    Background

    In 2019, more than $34.5 billion was spent on prescription drugs in Canada. However, little is known about the distribution of this...

    Mark Hofmeister, Ashwinie Sivakumar, ... Mina Tadrous in Journal of Pharmaceutical Policy and Practice
    Article Open access 17 March 2022
  16. Therapeutic effects of ginsenosides on breast cancer growth and metastasis

    Breast cancer is the most common cause of cancer-related deaths among women worldwide. Thus, the development of new and effective low-toxicity drugs...

    Yu** **, Diem Thi Ngoc Huynh, ... Kyung-Sun Heo in Archives of Pharmacal Research
    Article 24 August 2020
  17. Faecal Untargeted Metabolomics Analysis Elucidates the Antihyperglycaemic Effect of Surfactin in High-Fat Diet/Streptozotocin-Induced Type 2 Diabetic Mice

    Type 2 diabetes mellitus is accompanied by hyperglycaemia, liver dysfunction and intestinal dysbiosis. Bioactive peptides, as functional food,...

    **aoyu Chen, Jiaming Huang, ... Yingjian Lu in Revista Brasileira de Farmacognosia
    Article 06 December 2023
  18. Revolutionizing technologies of nanomicelles for combinatorial anticancer drug delivery

    Insufficient efficacy of current single drug therapy of cancers have led to the advancement of combination drug-loaded formulations. Specifically,...

    Min Jeong Jo, Ik Sup **, ... Dae Hwan Shin in Archives of Pharmacal Research
    Article 27 January 2020
  19. Combination of a chemopreventive agent and paclitaxel in CD44-targeted hybrid nanoparticles for breast cancer treatment

    The CD44 receptor, which is upregulated in many cancer cells, provides a selective cellular surface for targeted drug delivery systems. We developed...

    Bao Ngoc Tran, Hanh Thuy Nguyen, ... Chien Ngoc Nguyen in Archives of Pharmacal Research
    Article 12 October 2017
  20. A Survey of Survival Outcomes for Targeted Cancer Drugs Approved by the US Food and Drug Administration

    Background

    The last two decades have witnessed the vigorous development of targeted cancer drugs and the potent therapeutic effects of these drugs...

    Qian He, Qiu Li, ... Liming Shao in Therapeutic Innovation & Regulatory Science
    Article 08 March 2021
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