Search
Search Results
-
Pharmacological Aspects of the Use of Lipoic Acid (Review)
Lipoic (thioctic) acid (LA) [ R -5-(1,2-dithiolan-3-yl)pentanoic acid] is a natural compound that enters the human body with food. LA is used to treat...
-
Scope and challenges of nanoparticle-based mRNA delivery in cancer treatment
Messenger RNA (mRNA) recently emerged as an appealing alternative to treat and prevent diseases ranging from cancer and Alzheimer’s disease to...
-
Scaffolds of Purine Privilege for Biological Cytotoxic Targets: A Review
The primary aim of this review is to emphasize and guide the biological cytotoxic activities of purine scaffold, also with a focus on emerging purine...
-
Detonation Nanodiamonds as Promising Drug Carriers
Information on the use of detonation nanodiamonds (DNDs) in biomedical applications is reviewed. Literature data and our own results on the...
-
Parenteral
This chapter gives an overview of parenteral dosage forms and the rationale for their use. Parenterals are sterile preparations that are injected... -
Eczematous drug eruptions mostly manageable with emollients and corticosteroids
Eczematous drug eruptions (EDEs) constitute up to 10% of cutaneous drug reactions, with biologics and some newer cancer treatments and antivirals...
-
Linzagolix in moderate to severe symptoms of uterine fibroids: a profile of its use
Linzagolix (Yselty ® ) is an orally administered gonadotropin-releasing hormone receptor antagonist approved in the EU for the treatment of moderate to...
-
Chemotherapy-induced peripheral neuropathy—part 2: focus on the prevention of oxaliplatin-induced neurotoxicity
BackgroundChemotherapy-induced peripheral neuropathy (CIPN) is regarded as one of the most common dose-limiting adverse effects of several...
-
Classification of Companion Diagnostics: A New Framework for Biomarker-Driven Patient Selection
BackgroundModern personalized medicine strategies builds on therapy companion diagnostics to stratify patients into subgroups with differential...
-
Pharmacological Strategies to Overcome Tumor Resistance to Anticancer Hormonal, Targeted, and Immunotherapy
Possible molecular mechanisms of develo** tumor drug resistance to anticancer hormonal, targeted, and immunotherapy that are associated with the...
-
Biopharmaceutics
Biopharmaceutics, in connection with pharmacokinetics, is the field that investigates and describes everything that happens with a medicinal product... -
Cytotoxic Activity of Pimpinella isaurica and In Silico Analysis of Flavonoids
Pimpinella L., Apiaceae, is one of the largest genera and has a broad spectrum of biological or pharmacological activities including...
-
Identification of Confusing Medicine Proprietary Names: Toward Safe Medicine Use—A Cross-Sectional Study in Sri Lanka
BackgroundLook-alike sound-alike (LASA) medications have similar pronunciation (phonetic) and/or manifestation (orthographic), which could create...
-
Budget impact analysis of breast cancer medications: a systematic review
BackgroundBreast cancer (BC) is the most common cancer globally among women, with 2,261,419 new cases in 2020; systemic treatment may be...
-
Trends in Canadian prescription drug purchasing: 2001–2020
BackgroundIn 2019, more than $34.5 billion was spent on prescription drugs in Canada. However, little is known about the distribution of this...
-
Therapeutic effects of ginsenosides on breast cancer growth and metastasis
Breast cancer is the most common cause of cancer-related deaths among women worldwide. Thus, the development of new and effective low-toxicity drugs...
-
Faecal Untargeted Metabolomics Analysis Elucidates the Antihyperglycaemic Effect of Surfactin in High-Fat Diet/Streptozotocin-Induced Type 2 Diabetic Mice
Type 2 diabetes mellitus is accompanied by hyperglycaemia, liver dysfunction and intestinal dysbiosis. Bioactive peptides, as functional food,...
-
Revolutionizing technologies of nanomicelles for combinatorial anticancer drug delivery
Insufficient efficacy of current single drug therapy of cancers have led to the advancement of combination drug-loaded formulations. Specifically,...
-
Combination of a chemopreventive agent and paclitaxel in CD44-targeted hybrid nanoparticles for breast cancer treatment
The CD44 receptor, which is upregulated in many cancer cells, provides a selective cellular surface for targeted drug delivery systems. We developed...
-
A Survey of Survival Outcomes for Targeted Cancer Drugs Approved by the US Food and Drug Administration
BackgroundThe last two decades have witnessed the vigorous development of targeted cancer drugs and the potent therapeutic effects of these drugs...