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Development of Sample Preparation Methods for Vitamin-Mineral Complexes and Determination of their Elemental Composition Using Total Reflection X-Ray Fluorescence Analysis
Techniques to prepare samples of vitamin-mineral complexes (VMCs) for total reflection x-ray fluorescence (TXRF) analysis are described. Sample...
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Diuretic, Saluretic, and Ca2+-Sparing Effect of the Polygala cyparissias Methanol Extract, a Native Brazilian Medicinal Plant
Plants of the genus Polygala are used in folk medicine as diuretics. However, the effect of the extract of Polygala cyparissias A.St.-Hill.,...
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Evidence of the Impact of Interventions to Improve Medication Adherence
Although medicine expenditures represent one of the main budgetary elements for health care systems worldwide, it does not ensure their correct use... -
Emodin Attenuates Ozone-Induced Lung Injury Via TLR4/MYD88/NF-κB Signaling Pathways
In defense of the internal and external environment of the lung airway, airway epithelial cells play important roles in resisting external...
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Self-Therapy
Most of our genetically defined disease risks will involve so many genes that it will be unrealistic to erase them from our body by gene therapy.... -
Advanced Formulation Approaches for Proteins
Proteins and peptides are highly desirable as therapeutic agents, being highly potent and specific. However, there are myriad challenges with... -
Hydroxysafflor Yellow A Regulates Inflammation and Oxidative Stress by Suppressing the HIF-1α/JAK/STAT3 Signaling Pathway to Attenuate Osteoarthritis
Hydroxysafflor yellow A is extracted from Carthamus tinctorius L., Asteraceae, and has extensive pharmacological properties. In this study,...
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Methodically manage pain in older patients with Parkinson’s disease
Pain is a common, but often overlooked, non-motor symptom of Parkinson’s disease (PD), with nociceptive pain being most common. Structured...
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Scaffolds of Purine Privilege for Biological Cytotoxic Targets: A Review
The primary aim of this review is to emphasize and guide the biological cytotoxic activities of purine scaffold, also with a focus on emerging purine...
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Catha edulis and Cathinone Effect on Bone Parameters and Adipokines Gene Expression in Obese Male Mice
This study aims to determine the effects of Catha edulis (Vahl) Forssk. ex Endl., Celastraceae, and its bioactive alkaloid, cathinone, on liver...
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Public Understanding and Awareness of Isotretinoin Use and Safety in Al Ahsa, Eastern Saudi Arabia
BackgroundAcne vulgaris, a chronic inflammatory disease, is among the most common dermatologic conditions worldwide. In Saudi Arabia, Isotretinoin is...
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Mahanimbine Suppresses the Proliferation of Lung Cancer A549 Cells Via Inducing Intrinsic Apoptotic Pathway
Mahanimbine is a carbazole alkaloid that has been identified and isolated from several members of the Rutaceae family. Previous studies have...
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Role of Atractylenolide I in Cerebral Ischemia Reperfusion Injury
Atractylenolide I is one of the main sesquiterpene lactones of Atractylodes macrocephala Koidz., Asteraceae, and its biological functions involved in...
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Evaluation of the knowledge, practices, and attitudes of community pharmacists towards adverse effects of non-steroidal anti-inflammatory drugs (NSAIDs): a cross-sectional study
BackgroundNonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly used over-the-counter medications for the treatment of pain, fever, and...
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Psoralen Ameliorates Acetaminophen-Induced Acute Liver Injury by Inhibiting the Enzymatic Activity of CYP2E1
Excessive administration of the antipyretic and analgesic drug acetaminophen can cause acute liver injury. The mechanism is that a large amount of N -acetyl-...
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Laxative Effects and Phytochemical Analysis of Perilla frutescens Seed Oil by Using Gas Chromatography: A Good Source of Omega Fatty Acids
Perilla frutescens seeds contain fixed oil that is used as edible oil. Perilla seed oil is a good source of polyunsaturated fatty acids (PUFAs) such...
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Estrogen fluctuations during the menopausal transition are a risk factor for depressive disorders
Women are significantly more likely to develop depression than men. Fluctuations in the ovarian estrogen hormone levels are closely linked with...
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Daidzein Relieves Lipopolysaccharide-Induced Mastitis Through Inhibiting MAPKs and AKT/NF-κB P65 Signaling Pathways
Mastitis in dairy cattle is a serious pathological process that causes significant economic losses to the farming industry. Daidzein is a dietary...
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New Directions in the Development of Pharmacotherapy for Osteoarthrosis Based on Modern Concepts of the Disease Pathogenesis (A Review)
This review presents data on modern trends in the development of pharmacotherapy for osteoarthrosis, including growth factors and drugs affecting...
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Safety and Effectiveness of Multiple Switching Between Originators and Biosimilars: Literature Review and Status Report on Interchangeability
To date, numerous biosimilars are available in Europe and the practice of switching between originator and biosimilar or between two different...