Search
Search Results
-
Polyene Macrolide Antibotic Derivatives: Preparation, Overcoming Drug Resistance, and Prospects for Use in Medical Practice (Review)
Series of semi-synthetic polyene macrolide antibiotics (PMAs) that were prepared by chemical modification in original research by the authors are...
-
A herbal oil in water nano-emulsion prepared through an ecofriendly approach affects two tropical disease vectors
Lippia alba (Mill.) N.E.Br. ex Britton & P. Wilson, Verbenaceae, is considered a great source of a bioactive volatile oil. Due to the wide range of...
-
Modified Physicochemical Properties of Acidic Model Drugs Immobilized on Fe3O4Magnetic Iron Oxide Nanoparticles
Nanoparticles are now extensively evaluated as drug carriers. The main objective of the present work was to evaluate the difference in...
-
Emerging potential of stimulus-responsive nanosized anticancer drug delivery systems for systemic applications
The development of novel drug delivery systems based on well-defined polymer therapeutics has led to significant improvements in the treatment of...
-
Diphtheria toxoid nanoparticles improve learning and memory impairment in animal model of Alzheimer’s disease
BackgroundAlzheimer’s disease (AD) is a neurodegenerative disorder involving memory. The present study aimed at evaluating the effects of...
-
Detonation Nanodiamonds as Promising Drug Carriers
Information on the use of detonation nanodiamonds (DNDs) in biomedical applications is reviewed. Literature data and our own results on the...
-
Peptide Phage Display: Molecular Principles and Biomedical Applications
Phage display (PD) is a technology based on the presentation of functional exogenous peptides on the capsid surface of bacteriophages. PD is...
-
On the use of nanotechnology-based strategies for association of complex matrices from plant extracts
Depending on the method of extraction, plant extracts can contain an enormous variety of active molecules, such as phenolic compounds, essential...
-
Central nervous system and analgesic profiles of Lippia genus
Many people use medicinal plants to relieve disorders related to the central nervous system, such as depression, epilepsy, anxiety and pain, even...
-
Synthesis of arbutin–gold nanoparticle complexes and their enhanced performance for whitening
Arbutin, a natural polyphenol, possesses numerous biological activities including whitening, anti-oxidant, anti-cancer, anti-inflammatory activities,...
-
In vitro release and anti-herpetic activity of Cymbopogon citratus volatile oil-loaded nanogel
This study aimed to prepare hydrogel containing Cymbopogon citratus (DC.) Stapf, Poaceae, volatile oil encapsulated in poly ( d, l -lactide-co-glycolide...
-
Cytotoxic Activity and Kinetic Release Study of Lovastatin-Loaded Ph-Sensitive Polymersomes
Triblock poly(ε-caprolactone) – poly(ethylene glycol) – poly(ε-caprolactone) (PCL-PEG-PCL) copolymers were synthesized and used to prepare...
-
Of Straws, Camels, Research Regulation, and IRBs
Institutional review boards (IRBs) have become beleaguered by a growth in responsibilities related to research oversight in the past several decades....
-
Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Emerging Lipid Based Drug Delivery Systems
In the past decade, research in the area of nanodrug delivery has reached a new height with the advent of lipid based nanodrug delivery systems....
-
Recent advances in physiologically based pharmacokinetic and pharmacodynamic models for anticancer nanomedicines
Nanoparticles (NPs) have distinct pharmacokinetic (PK) properties and can potentially improve the absorption, distribution, metabolism, and...
-
Ag – ZnO Nanocomposites Cause Cytotoxicity and Induce Cell Cycle Arrest in Human Gastric and Melanoma Cancer Cells
Zinc oxide nanoparticles are used increasingly as antimicrobial and therapeutic agents, and the addition of metal ions such as silver may improve...
-
Nanostructured lipid carriers: A potential use for skin drug delivery systems
Skin application of pharmaceutical products is one of the methods used for drug administration. The problem of limited drug penetration via topical...
-
Evaluation of epithelial transport and oxidative stress protection of nanoengineered curcumin derivative-cyclodextrin formulation for ocular delivery
Ocular drug delivery has been a well-known route for the drug administration for the treatment of ocular diseases. However, numerous anatomical and...
-
Simple Extraction Cum RP-HPLC Method for Estimation of Nanotized Quercetin in Serum and Tissues of Mice
In recent years, several studies have focused on antioxidant, anti-inflammatory, and anti-cancer activities of quercetin (3,3′,4′,5,...
-
Nanosuspension of quercetin: preparation, characterization and effects against Aedes aegypti larvae
Aedes aegypti (Diptera: Culicidae) is the main vector of some neglected diseases, including dengue. It is very important to develop formulations that...