Search

Search Results

1. Relationship between thyroid hormones and central nervous system metabolism in physiological and pathological conditions

   Thyroid hormones (THs) play an important role in the regulation of energy metabolism. They also take part in processes associated with the central...

   Nadia Sawicka-Gutaj, Natalia Zawalna, ... Marek Ruchała in Pharmacological Reports

   Article 30 June 2022
   

2. Consider using selected antiepileptics to reduce the frequency of various types of headaches

   Antiepileptic drugs (AEDs) are among the best studied medications for the prevention of migraine and other headache disorders. The efficacy profiles...

   in Drugs & Therapy Perspectives

   Article 19 January 2019

3. Neurological consequences of COVID-19

   In December 2019, cases of pneumonia caused by infection with the previously unknown severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),...

   Waldemar Brola, Maciej Wilski in Pharmacological Reports

   Article 30 September 2022
   

4. Effects of carbamazepine, eslicarbazepine, valproic acid and levetiracetam on bone microarchitecture in rats

   Background

   Metabolic bone disease and fractures are a great problem for patients with epilepsy. The use of antiepileptic drugs (AEDs) is known to play...

   Sarah Seberg Diemar, Anne-Sophie Sejling, ... Niklas Rye Jørgensen in Pharmacological Reports

   Article 19 March 2020
   

5. Long-term vigabatrin treatment modifies pentylenetetrazole-induced seizures in mice: focused on GABA brain concentration

   Background

   The goal of our study was to examine the long-term effect of vigabatrin (VGB), a γ -aminobutyric acid aminotransferase (GABA-AT) inhibitor...

   Mariusz J. Świąder, Katarzyna Świąder, ... Stanisław J. Czuczwar in Pharmacological Reports

   Article Open access 20 December 2019
   

6. Capsaicin 8% dermal patch in peripheral neuropathic pain: a profile of its use

   A dermal patch containing a high (8%) capsaicin concentration (hereafter referred to as the capsaicin 8% dermal patch) [Qutenza ^® ] is a useful option...

   Sheridan M. Hoy in Drugs & Therapy Perspectives

   Article 24 December 2019

7. Synthesis of 4-Phenylpyrrolidone Derivatives with Anticonvulsant and Nootropic Activity

   New 4-phenylpyrrolidone derivatives were designed from racetam structures that combine nootropic and anticonvulsant activity. The proposed compounds...

   L. A. Zhmurenko, S. A. Litvinova, ... T. A. Gudasheva in Pharmaceutical Chemistry Journal

   Article 01 August 2019
   

8. Sigma receptors and neurological disorders

   Sigma receptors were identified relatively recently, and their presence has been confirmed in the central nervous system and peripheral organs....

   Agnieszka Piechal, Alicja Jakimiuk, Dagmara Mirowska-Guzel in Pharmacological Reports

   Article Open access 05 August 2021
   

9. Synthesis of Aminoalkyl Dibenzofuranone Oxime Derivatives Possessing Anticonvulsant Activity

   A new group of aminoalkyl dibenzofuranone oxime derivatives was designed and synthesized. Several compounds were found to exhibit anticonvulsant...

   L. A. Zhmurenko, S. A. Litvinova, ... T. A. Gudasheva in Pharmaceutical Chemistry Journal

   Article 11 January 2021
   

10. Synthesis and Anticonvulsant Activity of New 2-(4-Oxo-2-Thioxo-1,4-Dihydro-3(2h)-Quinazolinyl)Acetamides

    A search for new anticonvulsants led to a series of 2-(4-oxo-2-thioxo-1,4-dihydro-3(2 H )-quinazolinyl)- acetamides that were synthesized by reacting...

    N. D. Bunyatyan, H. I. Severina, ... Z. J. Khadzhieva in Pharmaceutical Chemistry Journal

    Article 21 April 2020
    

11. Unlocking the concealed targets using system biology map** for Alzheimer’s disease

    Background

    Alzheimer’s disease (AD) constitutes a neural loss in histology of brain with involvement of complex genomic and environmental factors....

    Poorvashree Joshi, Vikram Kawade, ... Mandakini Goel in Pharmacological Reports

    Article 29 June 2019

12. Influence of genetic variants of CYP2D6, CYP2C9, CYP2C19 and CYP3A4 on antiepileptic drug metabolism in pediatric patients with refractory epilepsy

    Background

    Identified the polymorphisms of CYP2D6, CYP2C9, CYP2C19 and CYP3A4 , within a rigorously selected population of pediatric patients with...

    Miguel A. López-García, Iris A. Feria-Romero, ... Sandra Orozco-Suarez in Pharmacological Reports

    Article 19 January 2017

13. Antiepileptogenic effects of Ethosuximide and Levetiracetam in WAG/Rij rats are only temporary

    Background

    WAG/Rij rats represent a validated genetic animal model of epileptogenesis, absence epilepsy and depressive-like comorbidity. Some...

    Antonio Leo, Carmen De Caro, ... Rita Citraro in Pharmacological Reports

    Article 24 April 2019

14. Risk of Extrapyramidal Syndromes Associated With Psychotropic Polypharmacy: A Study Based on Large-Scale Japanese Claims Data

    Background:

    Psychotropic polypharmacy is common in clinical practice although supporting evidence is limited. Extrapyramidal syndromes (EPS) are...

    Yoko Hirano in Therapeutic Innovation & Regulatory Science

    Article 13 January 2020

15. Analysis of the Cerebrovascular Effect of a Dibenzofuran Oxime Derivative

    The cerebrovascular properties of 3,4,6,7,8,9-hexahydrodibenzo[ b,d ]furan-1(2 H )-one O -(4-cinnamoyl)oxime (C ₂₁ H ₂₁ NO ₃ , GIZ-272) were studied. The...

    R. S. Mirzoyan, T. S. Gan’shina, ... L. M. Zhmurenko in Pharmaceutical Chemistry Journal

    Article 26 September 2020
    

16. Outcome measures in pediatric polypharmacy research: a sco** review

    Introduction

    Various methods have been used to interpret the reports of pediatric polypharmacy across the literature. This is the first sco** review...

    Negar Golchin, Hannah Johnson, ... Alexis Horace in Drugs & Therapy Perspectives

    Article 12 July 2019
    

17. DISCUSSION OF HERBAL DRUGS BASED ON THE BIOGENETIC CLASSIFICATION OF THEIR MAIN ACTIVE COMPONENTS

    Honey is prepared by honey-bees (Apis mellifera) from the nectar and honeydew of flowers. After chemical conversion by the gastric juices in the...

    Éva Szöke, Ágnes Kéry, Éva Lemberkovics in From Herbs to Healing

    Chapter 2023
    

18. Treatment of migraine: a review of disease burden and an update on the therapeutic landscape for pharmacists

    Given the key role of pharmacists as a healthcare resource for patients seeking treatment of headache associated with migraine, this review...

    Nishil Patel, Rebecca Barnhart, ... Tim Smith in Drugs & Therapy Perspectives

    Article Open access 05 December 2020
    

19. Mucuna pruriens Seed Extract: a Possible Protective Agent Against Ochratoxin A Neurodegeneration

    Mucuna pruriens (L.) DC., Fabaceae, an herbal phytomedicine used in Indian traditional Ayurvedic medicinal concoctions, is known to mediate...

    Pratiksha V. Bhat, Anand Tamatam, ... Mahantesh M. Patil in Revista Brasileira de Farmacognosia

    Article 27 April 2022
    

20. Intra-hippocampal microinjection of oxytocin produced antiepileptic effect on the pentylenetetrazol-induced epilepsy in rats

    Background

    In addition to its role as a circulating hormone, oxytocin can also act as a neurotransmitter and a neuromodulator within the brain. In...

    Amir Erfanparast, Esmaeal Tamaddonfard, Farzin Henareh-Chareh in Pharmacological Reports

    Article 12 March 2017