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Can research on entactogens contribute to a deeper understanding of human sexuality?
In recent years, scientific research into the therapeutic potential of psychedelic compounds has experienced a resurgence of interest. New studies...
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Effects of carvedilol on human prostate tissue contractility and stromal cell growth pointing to potential clinical implications
BackgroundApart from antagonizing ß-adrenoceptors, carvedilol antagonizes vascular α 1 -adrenoceptors and activates G protein-independent signaling....
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Cold chain management practices of non-vaccine commodities in public health facilities of Rwenzori Region, Western Uganda
BackgroundDespite the evidence that cold chain management practices affect the potency and effectiveness of both vaccines and non-vaccine...
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Patient Engagement and Patient Experience Data in Regulatory Review and Health Technology Assessment: A Global Landscape Review
BackgroundWorking with patients through meaningful patient engagement (PE) and incorporating patient experience data (PXD) is increasingly important...
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Development and Validation of a Quantitative Determination Method for Fluorothiazinone in Human Blood Plasma
An HPLC-MS/MS technique for quantitative determination of the new antibacterial drug fluorothiazinone in human blood plasma using an internal...
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Essential phospholipids impact cytokine secretion and alter lipid-metabolizing enzymes in human hepatocyte cell lines
BackgroundEssential phospholipids (EPL) are hepatoprotective.
MethodsThe effects on interleukin (IL)-6 and -8 secretion and on certain...
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Digital Health Technologies in Clinical Trials: An Ontology-Driven Analysis to Inform Digital Sustainability Policies
BackgroundDigital health technologies (DHTs) can facilitate the execution of de-centralized trials that can offer opportunities to reduce the burden...
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Thinking outside of the [cold] box: implementing a human-centered design approach to understand barriers and craft solutions to cold chain equipment maintenance in Niger
BackgroundVaccines require cold chain equipment (CCE) to ensure quality and potency, yet the risk of CCE failing is well-documented, often due to...
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Policy developer’s perceptions on the implementation of National Health Insurance in South Africa: a qualitative study
BackgroundUniversal health coverage has gained significant momentum internationally as the policy solution to address healthcare system deficiencies...
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Health supply chain system in Uganda: current issues, structure, performance, and implications for systems strengthening
BackgroundThe health supply chain system is essential for the optimum performance of the healthcare system. Despite increased investments in the...
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Following the COVID-19 playbook and battling another infodemic: conspiracy beliefs around human monkeypox among the Lebanese population
IntroductionThe non-endemic multicountry outbreak of monkeypox (MPX) has emphasized the issue of conspiracy theories that go viral in times of...
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Inventory management performance for family planning, maternal and child health medicines in public health facilities of West Wollega zone, Ethiopia
BackgroundInventory management is the heart of the supply system in improving availability of medicines, reducing the cost, and improving patient...
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Prevalence and correlates of burnout among Lebanese health care workers during the COVID-19 pandemic: a national cross-sectional survey
BackgroundThe COVID-19 pandemic has harshly burdened the healthcare systems. Health care workers (HCWs) are at substantial risk of infection and...
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When a neglected tropical zoonotic disease emerges in non-endemic countries: need to proactively fill the unveiled knowledge gaps towards human monkeypox among the Lebanese population
IntroductionThe ongoing multi-country outbreak of monkeypox (MPX) that emerges in non-endemic areas is a rare and unprecedented event that has...
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Global Regulatory and Public Health Initiatives to Advance Pediatric Drug Development for Rare Diseases
The literature thoroughly describes the challenges of pediatric drug development for rare diseases. This includes (1) generating interest from...
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The effect of selected aminoglycoside antibiotics on human serum albumin antioxidant activity: a spectroscopic and calorimetric comparative study
BackgroundHuman serum albumin (HSA) is a valuable component of non-enzymatic and endogenous antioxidant mechanisms. The antioxidant activity of HSA...
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The procurement and supply chain strengthening project: improving public health supply chains for better access to HIV medicines, Uganda 2011–2016
BackgroundWith countries moving towards reaching the UNAIDS 90-90-90 goal to achieve HIV epidemic control, there are going to be an unprecedented...
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The role of drug regulatory authorities and health technology assessment agencies in sha** incentives for antibiotic R&D: a qualitative study
BackgroundFew antibiotics have entered the market in recent years despite the need for new treatment options. Some of the challenges of bringing new...
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An Innovative Health Literacy Approach Designed to Improve Patient Understanding of Medication Labeling
ObjectiveLimited health literacy negatively impacts understanding of medication-related information. We describe an innovative methodology designed...
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Drug shops for stronger health systems: learning from initiatives in six LMICs
BackgroundPrivate sector retail pharmacies, or drug shops, play an important role in access to essential medicines and services in...
