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Safely disposing unused and unwanted prescription and over-the-counter medications: a public health, housing, and safety partnership in Framingham, MA
BackgroundThe improper disposal of unused drugs can harm the environment and living beings. Programs such as drug take-back bins encourage people to...
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Geriatric Health Services: Evidence and Impact in Pharmacy and Pharmaceutical Public Health in Low-to-Middle-Income Countries
Aging is a natural process and a special concern globally because it may necessitate special care for the geriatric population. Older age may be...
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Individualize treatment when prescribing medical cannabis to older patients as efficacy data remains limited
There is a growing interest in the use of cannabis for medical purposes, especially in older patients who experience pain, sleep difficulties, mood...
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Accelerating the Availability of Medications to Pediatric Patients by Optimizing the Use of Extrapolation of Efficacy
Improving pediatric therapeutic development is a mission of universal importance among health authorities, pharmaceutical companies, academic...
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Monitor growth changes from central nervous system stimulants in patients with attention-deficit/hyperactivity disorder
CNS stimulants used in the management of attention-deficit/hyperactivity disorder (ADHD) may suppress appetite, and thus growth. In randomised...
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Antibiotic utilization pattern in treatment of acute diarrheal diseases: the case of Hiwot Fana Specialized University Hospital, Harar, Ethiopia
BackgroundThe vast majority of acute diarrheal diseases are self-limiting and do not require treatment on a regular basis. Empirical antibiotics...
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Evidence of the Impact of Interventions to Prevent Obesity
Obesity has become a major global health challenge. Urgent global action and strong leadership is needed to help countries more effectively intervene...
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Current and emerging immunobiologic therapies for atopic dermatitis
Atopic dermatitis (AD) is a chronically relapsing inflammatory skin disease with a multifactorial etiology that affects up to 20% of children and up...
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When a neglected tropical zoonotic disease emerges in non-endemic countries: need to proactively fill the unveiled knowledge gaps towards human monkeypox among the Lebanese population
IntroductionThe ongoing multi-country outbreak of monkeypox (MPX) that emerges in non-endemic areas is a rare and unprecedented event that has...
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Nirmatrelvir plus ritonavir in COVID-19: a profile of its use
Oral nirmatrelvir plus ritonavir (Paxlovid ™ ) is an effective treatment option for coronavirus disease 2019 (COVID-19), the illness caused by severe...
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A closer look at the 2019 Beers criteria
Increased use of potentially inappropriate medications (PIMs) is one of the major issues arising in older adults. The use of PIMs has been found to...
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Extrapolation as a Default Strategy in Pediatric Drug Development
Pediatric drug development lags adult development by about 8 years (Mulugeta et al. in Pediatr Clin 64(6):1185–1196, 2017). In such context, many...
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COVID-19 and diabetes in 2020: a systematic review
Attempts were made to review the literature on diabetic patients who experience complications when they contract COVID-19, and to determine whether...
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Frailty and rate of fractures in patients initiating antihypertensive medications: a cohort study in primary care
BackgroundTreatment for hypertension improves cardiovascular outcomes. Frailty may be present in older people treated for hypertension, but...
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Olopatadine/mometasone combination nasal spray in allergic rhinitis: a profile of its use
Olopatadine/mometasone furoate combination nasal spray (Ryaltris ® ; referred to hereafter as olopatadine/mometasone), a convenient fixed-dose...
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Status of Planned and Ongoing Paediatric Trials Investigating COVID-19 Vaccines: A Cross-Sectional Study of Paediatric Clinical Trials Planned in Agreed PIPs and/or Registered in Clinical Trial Databases
BackgroundThe immune system matures throughout childhood; therefore, evidence about the safety and efficacy of vaccines for the prevention of...
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Unlocking the Potential: A Systematic Review of Master Protocol in Pediatrics
The use of master protocols allows for innovative approaches to clinical trial designs, potentially enabling new approaches to operations and...
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Differences in healthcare service utilization in patients with polypharmacy according to their risk level by adjusted morbidity groups: a population-based cross-sectional study
BackgroundPatients with polypharmacy suffer from complex medical conditions involving a large healthcare burden. This study aimed to describe the...
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Quantifying Clinical Trial Diversity in Pivotal Registration Trials of FDA Novel Drug Approvals
BackgroundHealth care inequity includes the lack of adequate representation of various populations in clinical trials. Government, academic and...
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Comparison between European Medicines Agency and US Food and Drug Administration in Granting Accelerated Marketing Authorizations for Covid-19 Medicines and their Utilized Regulations
BackgroundPrompted by the Covid-19 pandemic and the need to ensure timely and safe access to medicines during a pandemic, the aim of this study was...
