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Prospects for Production of Microencapsulated Medicines Based on Plant Extracts (Review)
Material devoted to the peculiarities of plant extract microencapsulation used for the development and production of drugs and active substances with...
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Dipeptidyl Peptidase-4 inhibitors use in type II diabetic patients in a tertiary hospital
BackgroundIn Malaysia, for more than a decade, dipeptidyl peptidase-4 inhibitors (DPP-4i) are among the oral antidiabetic medications used as...
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The impact of pharmacist interventions, follow-up frequency and default on glycemic control in Diabetes Medication Therapy Adherence Clinic program: a multicenter study in Malaysia
BackgroundPharmacist’s involvement in optimizing medication adherence among diabetic patients has been implemented for over a decade. Diabetes...
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Assessment of medication discrepancies with point prevalence measurement: how accurate are the medication lists for Swedish patients?
BackgroundMedication discrepancies are common, potentially harmful and may result from poor medication information across medical records. Our aim...
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Phytochemistry and pharmacological activity of the genus artemisia
Artemisia and its allied species have been employed for conventional medicine in the Northern temperate regions of North America, Europe, and Asia...
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Antihyperglycemic and Antihyperlipidemic Evaluation of Zingiber officinale, Anethum graveolens and Citrullus colocynthis Extracts with Different Polarities in Streptozotocin-Induced Diabetic Rats
Zingiber officinale (ginger , II ), Citrullus colocynthis (CC, III ) and Anethum graveolens (dill, IV ) are functional medicinal plants containing...
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The potential of therapeutic strategies targeting mitochondrial biogenesis for the treatment of insulin resistance and type 2 diabetes mellitus
Type 2 diabetes mellitus (T2DM) is a persistent metabolic disorder marked by deficiencies in insulin secretion and/or function, affecting various...
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Chemistry and Pharmacology of Alkylamides from Natural Origin
Interest in alkylamide, as a class of compound, has grown tremendously in recent years. This interest is due to the many presumed benefits in food,...
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Impact of FDA-Required Cardiovascular Outcome Trials on Type 2 Diabetes Clinical Study Initiation From 2008 to 2017
Background:Since 2008, the US Food and Drug Administration (FDA) has required that drug manufacturers conduct postmarket cardiovascular outcomes...
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Biochanin A Attenuates Hyperglycemia in High-Fat Diet–Streptozotocin–Induced Diabetic Rats by Modulating the Activities of Carbohydrate-Metabolizing Enzymes in Vital Organs
Medicinal plants have long been used for phyto therapy, and various herbal medicines have been used for diabetes treatment. The bioactive components...
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Analysis of Artabotrys hexapetalus Stem Bark and Leaf Ethanol Extracts as α-Glucosidase Inhibitors: In Vitro Analysis, LC-MS/MS, Machine Learning, and Molecular Docking
Artabotrys hexapetalus (L.f.) Bhandari, Annonaceae, is one of Artabotrys species found in Asia, such as Sri Lanka, India, China, Malaysia, Indonesia,...
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Antioxidant Action of Hesperis matronalis L. in Chronic Experimental Diabetes
Hesperis matronalis L. is an herbaceous species used in traditional medicine for stimulatory, antiscorbutic, diuretic, diaphoretic and expectorant...
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Utilization of Phytochemicals as Nutraceutical in the Prophylaxis of Dengue
Every year, during the monsoon season, dengue, an infectious disease transmitted by the Aedes aegypti mosquito and caused by the dengue virus,...
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Future Perspectives for the Treatment of Diabetes: Importance of a Regulatory Framework
BackgroundThe number of diabetes patients is steadily increasing worldwide. Consequently, the social burden of diabetes is huge, requiring urgent...
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Sesquiterpene Coumarins from Ferula narthex 15-LOX, α-Glucosidase Inhibition and Molecular Docking Studies
Ferula narthex Boiss., Apiaceae, is commonly used in Pakistan and India as spice and it is associated with diverse biological activities including...
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Hypoglycemic Activity of Glycyrrhizic Acid and Some of its Derivatives in the Alloxan Diabetes Model in Rats
The hypoglycemic activity of glycyrrhizic acid (GA, I ), its trisodium ( II ) and sodium-dilithium salts ( III ), and a conjugate with L -methionine methyl...
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Synthesis and Antiulcer Activity of Aromatic and Heterocyclic Amides of 3-O-Acetylglycyrrhetic Acid
C30-amides of 3- O -acetylglycyrrhetic acid containing aromatic and heterocyclic pharmacophores were synthesized by the acid chloride method. The...
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UHPLC, ATR-FTIR Profiling and Determination of 15 LOX, α-Glucosidase, Ages Inhibition and Antibacterial Properties of Citrus Peel Extracts
Diabetes mellitus (DM) has a worldwide prevalence with very alarming situation in low-income and develo** countries including Pakistan. During this...
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Inhibition of α-Amylase and α-Glucosidase by New β-Aminopropionamidoxime Derivatives
New antidiabetic agents are being sought because of the global problem with diabetes. Amidoxime derivatives are known to have antidiabetic activity....
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In Vitro Evaluation of Antioxidant, Antimicrobial, Cytotoxic, Anti-Inflammatory, Anti-Aging, Enzyme Inhibition Potential, and HPLC Analysis of Traditionally Used Plant Delphinium Uncinatum Wall
Delphinium uncinatum Wall. (Ranunculaceae) is a native medicinal plant found on the sub-continent that is utilized to cure various human diseases....