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Showing 21-40 of 262 results
  1. Synthesis and evaluation of antitumor activity of novel 1,4-Naphthoquinone derivatives (IV)

    1,4-Naphthoquinones are widely distributed in nature and many clinically important antitumor drugs containing a quinone moiety, such as...

    Bok Hee Kim, Jikang Yoo, ... Yongseog Chung in Archives of Pharmacal Research
    Article 01 February 2006
  2. Synthesis of Trinorditerpenoid Derivatives and Evaluation of Antimicrobial and Cytotoxic Activity

    The synthesis of optically active trinorditerpenes was carried out, and their antimicrobial and antitumor activity was tested. The synthetic...

    R. Alonso, H. Gomis, ... C. Sajo in Chemistry of Natural Compounds
    Article 01 May 2005
  3. Synthesis of DNA Using a New Two-Step Cycle

    For the first time a new, two-step method is described for synthesizing deoxyribonucleic acid. The approach uses 5′-carbonate protected...
    Douglas J. Dellinger, Jason R. Betley, ... Marvin H. Caruthers in Oligonucleotide Synthesis
    Protocol 2005
  4. Synthesis and Biological Activity of Hydroxyphencyclidine Homologs

    A series of phencyclidine homologs was synthesized by reductive cyclization of substituted ω-chlorine-substituted l-N-[l-( p -hydroxybenzyl)cyclohexyl]a...

    V. A. Glushkov, L. V. Anikina, ... A. G. Tolstikov in Pharmaceutical Chemistry Journal
    Article 01 March 2005
  5. Synthesis and evaluation of antitumor activity of 2- and 6-[(1,3-benzothiazol-2-yl)aminomethyl]-5,8-dimethoxy-1,4-naphthoquinone derivatives

    2- or 6-Substituted BZT-N derivatives were synthesized, and their cytotoxic activity against cancer L1210 and SNU-1 cells was examined. The antitumor...

    Yongseog Chung, Young-Kook Shin, ... Hoon Cho in Archives of Pharmacal Research
    Article 01 September 2004
  6. Synthesis and antiviral activity of novel methylene cyclopropyl nucleosides

    Novel exomethylene cyclopropyl nucleosides were synthesized as potential antiviral agents. The key intermediate 5 was synthesized in 4 steps, from...

    Eun Yee Kwak, Joon Hee Hong, ... Bo Gil Choi in Archives of Pharmacal Research
    Article 01 December 2000
  7. Synthesis ofLepidoptera pheromones using acetylenes

    Syntheses of acetogenin pheromones using acetylene derivatives are reviewed.

    V. N. Odinokov in Chemistry of Natural Compounds
    Article 01 January 2000
  8. Development of new dihydropyran linker for solid-phase reaction

    The linker which plays a role in connecting a polymer with a scaffold has become an important part in solid-phase reaction. To develop a new linker...

    Joon-Hyung Ryu, **-Hyun Jeong in Archives of Pharmacal Research
    Article 01 December 1999
  9. The synthesis of labeled sterols

    This review presents a discussion of methods for the chemical synthesis of sterols labeled with hydrogen and carbon isotopes.

    N. V. Kovganko, S. K. Ananich in Chemistry of Natural Compounds
    Article 01 July 1999
  10. The chemical synthesis of sterols: Latest advances

    This review discusses the results of investigations on the chemical synthesis of sterols during 1981–1996.

    N. V. Kovganko, S. K. Ananich in Chemistry of Natural Compounds
    Article 01 May 1999
  11. Olefination of aliphatic aldehydes in the synthesis of mono-, di-, and trienic pheromones of linear structure

    This review systematizes information published mainly in the last 15 years on the use of the olefination of aliphatic aldehydes (the Wittig reaction...

    V. N. Odinokov in Chemistry of Natural Compounds
    Article 01 May 1999
  12. Reactivity and suitability oft-boc-protected thiophosphotyrosine intermediate analogs for the solid or solution phase peptide synthesis

    N-(tert -Butoxycarbonyl)- O -(dimethylthiophosphono)-L-tyrosine ( 6 ) and N-(tert -butoxycarbony)- O -(dicyanoethylthiophosphono)-L-tyrosine ( 15 ) were...

    Eun-kyung Kim, Heesung Choi, Eung-Seok Lee in Archives of Pharmacal Research
    Article 01 June 1998
  13. Synthesis ofAchlya polyhydroxysteroids

    This review generalizes the results of investigations on the chemical synthesis of sex hormones of aquatic fungi of the Achlya genus.

    N. V. Kovganko, Zh. N. Kashkan in Chemistry of Natural Compounds
    Article 01 January 1998
  14. Recent advances in the chemical synthesis of ecdysteroids and compounds related to them

    This review generalizes information on methods of synthesizing ecdysteroids and substances structurally close to them published in the literature...

    N. V. Kovganko in Chemistry of Natural Compounds
    Article 01 September 1997
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