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Co-Administration of Polyamines with Rutin and Metformin Ameliorates Streptozotocin-Induced Diabetes: Possible Involvement of Antioxidants, Inflammatory Cytokines, and Biochemical Paradigms
The present investigation was undertaken to study the role of polyamines and rutin in combination with metformin in the streptozotocin-induced...
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Study on the Anti-inflammatory Activity of N-(E)-p-Coumaroyl Tyrosine In Vitro and In Vivo
N -( E )- p -Coumaroyl tyrosine is a phenolic amino acid derivative extracted from the Abrus mollis Hance, Syn of Abrus melanospermus subsp. melanospermus ,...
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Anti-melanogenic and Anti-inflammatory Activities of Hibiscus sabdariffa
Hibiscus sabdariffa L., Malvaceae, is traditionally cultivated for its stem, leaves, calyces, and seeds as all parts have industrial, medicinal, and...
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Anti-elastase, Anti-tyrosinase, and Anti-inflammatory Activities of Three Compounds Isolated from Psorospermum aurantiacum: In Silico and In Vitro Assays
The hexane fraction of Psorospermum aurantiacum Engl., Hypericaceae, was found to prevent photo aging in skin cells lines. Therefore, this research...
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Evaluation of analgesic and anti-inflammatory activity of purine-2,6-dione-based TRPA1 antagonists with PDE4/7 inhibitory activity
BackgroundTo verify the validity of the proposed pain treatment approach, which is based on concomitant blocking of the Transient Receptor Potential...
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Therapeutic Effects of Resveratrol in Inflammatory Bowel Diseases: Shedding Light on the Role of Cellular and Molecular Pathways
Inflammatory bowel disease is a debilitating idiopathic inflammatory condition of the gastrointestinal tract. Generally, this illness contains two...
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Jacareubin inhibits TLR4-induced lung inflammatory response caused by the RBD domain of SARS-CoV-2 Spike protein
BackgroundCOVID-19, the disease caused by SARS-CoV-2 virus infection, has been a major public health problem worldwide in the last 2 years....
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Sestrin2 induction contributes to anti-inflammatory responses and cell survival by globular adiponectin in macrophages
Adiponectin, an adipose tissue-derived hormone, exhibits a modulatory effect on cell death/survival and possesses potent anti-inflammatory...
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Natural Populations of Galphimia spp. Attenuates In Vitro and In Vivo Inflammatory Responses
The genus Galphimia , Malpighiaceae, is widely distributed in Mexico and represented by 22 species including medicinal species. The sedative and...
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Systematic Review of Anti-inflammatory Agents from Aspergillus Species
Most species of fungi are recognized as etiological agents from a vast number of human and animal diseases. Contrarily, in the Natural Products...
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Formyl peptide receptor 2, as an important target for ligands triggering the inflammatory response regulation: a link to brain pathology
Formyl peptide receptors (FPRs) belong to the family of seven-transmembrane G protein-coupled receptors. Among them, FPR2 is a low affinity receptor...
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Ameliorating effects of berberine on sepsis-associated lung inflammation induced by lipopolysaccharide: molecular mechanisms and preclinical evidence
As a life-threatening disorder, sepsis-associated lung injury is a dysregulated inflammatory response to microbial infection, characterized by the...
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Manage endodontic pain with a combination of analgesics, including non-steroidal anti-inflammatory drugs
Endodontic pain often presents as a dental emergency as apprehensive patients defer what they anticipate as a painful experience. Most correctly...
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Role of specialized pro-resolving lipid mediators and their receptors in virus infection: a promising therapeutic strategy for SARS-CoV-2 cytokine storm
Unexpected viral infections outbreaks, significantly affect human health, leading to increased mortality and life disruption. Among them is the...
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Tartary Buckwheat Flavonoids Relieve Non-alcoholic Fatty Liver Disease by Inhibiting Lipid Accumulation, Inflammation, and Regulating Intestinal Flora
Non-alcoholic fatty liver disease is characterized by liver damage and steatosis, which is often accompanied by inflammation. Tartary buckwheat...
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Innate immune sensing of pathogens and its post-transcriptional regulations by RNA-binding proteins
Innate immunity is one of the most ancient and conserved aspect of the immune system. It is responsible for an anti-infective response and has been...
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Anti-inflammatory and Anti-arthritic Activities of Glycosylated Flavonoids from Syzygium jambos in Edematogenic Agent-Induced Paw Edema in Mice
Two glycosylated flavonoids, the quercetin-3- O -β- d -xylofuranosyl-(1 → 2)-α- l -rhamnopyranoside and myricetin-3- O -β- d -xylofuranosyl-(1 → 2)-α- l -rhamnopy...
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Solid-Phase Fluorimetric Determination of Some Nonsteroidal Anti-Inflammatory Drugs in Medicines with the Aid of a Smartphone
A fast and simple method for determining the active ingredients of non-steroidal anti-inflammatory drugs (NSAIDs) meloxicam and tolfenamic,...
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Ginsenoside from ginseng: a promising treatment for inflammatory bowel disease
Inflammatory bowel disease (IBD) is an autoimmune disease mediated by immune disorder and termed as one of the most refractory diseases by the Word...
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Role of Atractylenolide I in Cerebral Ischemia Reperfusion Injury
Atractylenolide I is one of the main sesquiterpene lactones of Atractylodes macrocephala Koidz., Asteraceae, and its biological functions involved in...
