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Microbial Transformation of Azorellane and Mulinane Diterpenoids
Microbial transformation is an alternate strategy to obtain novel derivatives from natural products using whole cells or enzymes because of their...
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Synthesis and Antidepressant Activity of Thietane-Containing 4-(2-oxo-2-phenylethyl)-1H-1,2,4-triazol-4-ium Bromides
Thietane-containing 4-(2-oxo-2-phenylethyl)-1 H -1,2,4-triazol-4-ium bromides were synthesized by quaternization of thietanyltriazoles with phenacyl...
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New phenalenone derivatives from the Hawaiian volcanic soil-associated fungus Penicillium herquei FT729 and their inhibitory effects on indoleamine 2,3-dioxygenase 1 (IDO1)
Phenalenone derivatives sourced from fungi are polyketides that have attracted significant interest because of their diverse chemical structures and...
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Indole Compounds from Raphanus sativus Seeds
Two new indole compounds, (3 S )-2-(3,4-dihydroxy-2-oxoindole-3)-acetamide and indole-3-acetonitrile-6- O -β- D -(6′- O -acetyl) glucoside, were isolated...
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Chemical Constituents and Anti-inflammatory, Antinociceptive, and Antioxidant Activities of Salvia melissiflora Aerial Parts
Chromatographic fractionation of dichloromethane and ethanol extracts of Salvia melissiflora Benth., Lamiaceae, aerial parts led to the...
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A New Compound from Monascus Floridanus
A phytochemical investigation of the fungus Monascus floridanus resulted in a novel pyrrole compound, floridapyrrole. The structure of the new...
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Cucurbitane Triterpene Glycosides from the Roots of Wilbrandia hibiscoides
In this study, we isolated and identified cucurbitane triterpene glycosides of Wilbrandia hibiscoides Silva Manso contributing to the phytochemistry...
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A New Diarylheptanoid from the Twigs of Quercus Acutissima and their Neuroprotective Activity
A new diarylheptanoid glycoside, acutissioside A ( 4 ), along with five known diarylheptanoids ( 1–3 , 5 , 6 ) was isolated from the twigs of Quercus...
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Cytotoxic Hydroperoxycochliodinol Derivative from Endophytic Chaetomium sp. Isolated from Salvia officinalis
The endophytic fungus Chaetomium sp. was separated from the medicinal plant Salvia officinalis growing in Egypt and cultivated on solid rice medium....
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Diterpenoid Alkaloids from the Roots of Aconitum iochanicum
Three new diterpenoid alkaloids, namely 1- N -deethyl-1,16-demethoxy-1,16-dihydroxy- N (19)-enaustroconitine A ( 1 ), 1- N -deethyl-1,16-demethoxy-1,16-dihydroxy-18-methoxy-...
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A New Anticancer Bisflavan-3-Ol from Boerhavia elegans
A new a bisflavan-3-ol, boerhavianane ( 1 ), was isolated from Boerhavia elegans L. The structure of the flavanol dimer was elucidated by detailed...
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α- and γ-Apienes, Ferovinal, and Ferocin from Ferula ovina
The esters ferovinal ( α -apiene-type) and ferocin ( γ -apiene-type) were isolated from Ferula ovina. Their structures were established by analyzing IR,...
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Cytotoxic Plumbagin-5-O-α-l-Rhamnopyranoside from Plumbago indica
The chemical investigation of Plumbago indica L., Plumbaginaceae, has led to isolation and identification of one new naphthoquinone glycoside...
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A New Phenolic Glycoside from Viburnum Melanocarpum Fruits and its α-Glucosidase Inhibitory Activity
A new phenolic glycoside 1, together with its enantiomer (2), was isolated from the ethanolic extract of Viburnum melanocarpum P. S. Hsu fruits by...
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Ferovinolal, a New Humulane from Ferula ovina
The new humulane-type ( α -apiene) ester ferovinolal was isolated from Ferula ovina roots. The structure of ferovinolal was elucidated using IR, PMR, 13 ...
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2-Geranyl-1-methoxyerythrabyssin II alleviates lipid accumulation and inflammation in hepatocytes through AMPK activation and AKT inhibition
A growing proportion of the global adult and pediatric populations are currently affected by nonalcoholic steatohepatitis (NASH), leading to rising...
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Amarisolide H and 15-epi-Amarisolide H, Two Diterpenoid Glucosides from Salvia circinnata
The HPLC–PDA profiling of an acetone-soluble extract of the leaves of Salvia circinnata Cav. (Syn. Salvia amarissima Ortega), Lamiaceae, collected at...
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Trichothecene and tremulane sesquiterpenes from a hallucinogenic mushroom Gymnopilus junonius and their cytotoxicity
Gymnopilus junonius (Fr.) P. D. Orton (Cortinariaceae) is a hallucinogenic mushroom, a well-known poisonous mushroom that is widely known as "big...
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Steroids from Dendronephthya mucronata and Their Inhibitory Effects on Lipopolysaccharide-Induced No Formation in RAW264.7 Cells
Four pregnane-type steroids including the new compound 5- α -pregn-20-en-3,6-dione ( 1 ) and two known cholestane-type steroids were isolated from the...
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QUALITY REQUIREMENTS FOR HERBAL DRUGS; ANALYTICAL METHODS
In the broadest sense, all plants that are used for healing purposes, based on either traditional use or scientific data, are referred to as...