Search
Search Results
-
Metyrapone in Cushing’s syndrome: a profile of its use
Metyrapone (Metopirone ® ), a pyridine derivative, is a useful treatment option for the management of patients with endogenous Cushing’s syndrome,...
-
Lipid-lowering drugs and cancer: an updated perspective
Statins and non-statin medications used for the management of dyslipidemia have been shown to possess antitumor properties. Since the use of these...
-
Effect of Glycyrrhizic Acid on the Viability of Hela Cervical Adenocarcinoma Cell Line at Different Concentrations of Sex Steroid Hormones
The persistence of human papillomavirus affects the processes of proliferation and differentiation of the stratified squamous epithelium of the...
-
Various Formulations of Glycyrrhizic Acid and the Possibility of Their Use in Virus-Associated and Inflammatory Diseases
Pharmaceuticals containing glycyrrhizic acid that exhibit a pleiotropic effect and reduce the risk of progression of cervical lesions associated with...
-
The role of bidirectional communication between the adipokines and the endogenous opioid system in an experimental mouse model of colitis-associated colorectal cancer
BackgroundColorectal cancer (CRC) is one of the leading causes of death globally. Multiple factors may contribute to the pathogenesis of CRC,...
-
Ketoconazole in Cushing’s syndrome: a profile of its use
Ketoconazole (Ketoconazole HRA™), an imidazole derivative, is a useful treatment option in the management of endogenous Cushing’s syndrome in adults...
-
Potential Role of Herbal- and Bacterial-Derived Peptides Against Colorectal Cancer
Despite recent advances in the prevention, diagnosis, and treatment of colorectal cancer as the third cause of cancer death, the development of...
-
Advances in plant-derived natural products for antitumor immunotherapy
In recent years, immunotherapy has emerged as a novel antitumor strategy in addition to traditional surgery, radiotherapy and chemotherapy. It...
-
Regulation of PKB/Akt-pathway in the chemopreventive effect of lactoferrin against diethylnitrosamine-induced hepatocarcinogenesis in rats
BackgroundAbnormal activation of protein kinase B (PKB) is associated with many cancers. This makes inhibition of PKB signaling pathway a promising...
-
Targeting ROCK/LIMK/cofilin signaling pathway in cancer
Rho-associated coiled-coil-containing protein kinase (ROCK)/Lin11, Isl-1 and Mec-3 kinase (LIMK)/cofilin-signaling cascades are stimulated by...
-
Chemoprevention of Radiation-Induced Carcinogenesis Using Decoction of Meadowsweet (Filipendula Ulmaria) Flowers
The ability of the decoction of meadowsweet flowers ( Filipendula ulmaria , FU) to inhibit tumor development in female LIO rats was demonstrated using...
-
Fate and distribution of kynurenic acid administered as beverage
BackgroundKynurenic acid (KYNA) is a biologically active metabolite of tryptophan exerting action on several receptors located in the brain and...
-
Selenomethionine potentiates the impact of vitamin D on thyroid autoimmunity in euthyroid women with Hashimoto’s thyroiditis and low vitamin D status
BackgroundBoth exogenous vitamin D and selenium reduce thyroid antibody titers. The aim of the study was to investigate whether the impact of vitamin...
-
Biological Activity of S-Containing Monoterpenoids
S-containing mono- and bicyclic monoterpenoids were reviewed with respect to antifungal, anti-inflammatory, anti-helicobacter, anticlotting,...
-
Manage psychiatric symptoms in Cushing’s syndrome by controlling cortisol levels and usual psychiatric therapy
Depression and anxiety disorders are common in Cushing’s syndrome (CS); mania and psychosis may also occur. Use screening tools to identify...
-
Comprehensive chemical analysis of the flower buds of five Lonicera species by ATR-FTIR, HPLC-DAD, and chemometric methods
Lonicera japonica Thunb., Caprifoliaceae, has been employed in traditional Chinese medicine for thousands of years. However, it is frequently...
-
Antipsychotic dopamine receptor antagonists, cancer, and cancer stem cells
Cancer is one of the deadliest diseases in the world. Despite extensive studies, treating metastatic cancers remains challenging. Years of research...
-
Impact of morin-5′-sulfonic acid sodium salt on cyclophosphamide-induced gastrointestinal toxicity in rats
BackgroundThe aim of this study was to evaluate the effect of morin-5′-sulfonic acid sodium salt (NaMSA) on cyclophosphamide-induced gastrointestinal...