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DMT1-dependent endosome-mitochondria interactions regulate mitochondrial iron translocation and metastatic outgrowth
Transient early endosome (EE)-mitochondria interactions can mediate mitochondrial iron translocation, but the associated mechanisms are still...
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Cochlear Implant Translocation: Diagnosis, Prevention, and Clinical Implications
Purpose of ReviewTo summarize the literature on scalar translocation of cochlear implant (CI) electrode arrays (EAs), including diagnosis,...
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Ameliorative Effects of Larazotide Acetate on Intestinal Permeability and Bacterial Translocation in Acute Pancreatitis Model in Rats
BackgroundIntestinal barrier dysfunction in acute pancreatitis (AP) may progress to systemic inflammatory response syndrome (SIRS) and multi-organ...
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Primary cutaneous CD30+ lymphoproliferative disorders with DUSP22 translocation
Primary cutaneous CD30+ lymphoproliferative disorders (LPD) encompass a broad category of clonal T cell proliferations with varied clinical...
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Geography and health: role of human translocation and access to care
Natural, geographical barriers have historically limited the spread of communicable diseases. This is no longer the case in today’s interconnected...
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Differences in Bacterial Translocation and Liver Injury in Ethanol Versus Diet-Induced Liver Disease
BackgroundAlcohol-associated liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH) are two of the...
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Dorsal capsule release and lateral band translocation for a stiff swan neck deformity without articular involvement
BackgroundThe treatment for proximal interphalangeal joint (PIP) stiffness in extension requires extensor tenolysis, concomitant procedures to...
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The first case of six-way complex translocation of t(4;7;9;22;8;14) in a patient with chronic myeloid leukemia
In chronic myeloid leukemia (CML), patients exhibit the t(9;22)(q34.1;q11.2) translocation, resulting in the formation of a Philadelphia chromosome...
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HuR-mediated nucleocytoplasmic translocation of HOTAIR relieves its inhibition of osteogenic differentiation and promotes bone formation
Bone marrow mesenchymal stem cell (BMSC) osteogenic differentiation and osteoblast function play critical roles in bone formation, which is a highly...
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t(1;4) translocation in a child with acute lymphoblastic leukemia: a case report
BackgroundAcute lymphoblastic leukemia is the most common childhood cancer, with an 80% frequency in children between 1 and 10 years old. The outcome...
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Translocation of bacterial LPS is associated with self-reported cognitive abilities in men living with HIV receiving antiretroviral therapy
BackgroundGut damage allows translocation of bacterial lipopolysaccharide (LPS) and fungal β-D-glucan (BDG) into the blood. This microbial...
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Nuclear translocation of Gasdermin D sensitizes colorectal cancer to chemotherapy in a pyroptosis-independent manner
Gasdermin D (GSDMD) has recently been identified as a cytoplasmic effector protein that plays a central role in pyroptosis of immune cells. However,...
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The effect of carrier characteristics and female age on preimplantation genetic testing results of blastocysts from Robertsonian translocation carriers
PurposeTo analyze factors affecting segregation and ploidy results from Robertsonian carriers, and determine chromosomes involved impact chromosome...
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A case report: anatomical translocation in tibial insertion of semitendinosus tendon after tibial lengthening
BackgroundThere is the most common method for arthroscopic anterior cruciate ligament (ACL) reconstruction by using the semitendinosus and gracilis...
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Structural insights into substrate recognition and translocation of human peroxisomal ABC transporter ALDP
Dysfunctions of ATP-binding cassette, subfamily D, member 1 (ABCD1) cause X-linked adrenoleukodystrophy, a rare neurodegenerative disease that...
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Adipsin inhibits Irak2 mitochondrial translocation and improves fatty acid β-oxidation to alleviate diabetic cardiomyopathy
BackgroundDiabetic cardiomyopathy (DCM) causes the myocardium to rely on fatty acid β-oxidation for energy. The accumulation of intracellular lipids...
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Clinicopathologic, treatment and prognosis study of 46 Xp11.2 translocation/TFE3 gene fusion renal cell carcinomas
PurposeTo report the clinicopathological features and mid- to long-term oncologic results of Xp11.2 translocation/transcription factor E3 ( TFE3 )...
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Restoration of the Mucosal IgA Response by Improving CD4+ T Pyroptosis Fails to Attenuate Gut Bacterial Translocation and Organ Damage After LPS Attack
BackgroundCurrently, the mechanisms of impaired gut mucosal immunity in sepsis remain unclear. Gut immunoglobulin A (IgA) is an important defense...
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A study to evaluate association of nuclear grooving in benign thyroid lesions with RET/PTC1 and RET/PTC3 gene translocation
IntroductionPapillary thyroid carcinoma (PTC) is the most common malignant lesion of the thyroid characterized by unique histological features like...
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Partial trisomy 9p and partial monosomy 7p of an infant inherited from maternal balanced translocation: a case report
BackgroundSubchromosomal deletions and duplications are the leading cause of congenital malformations and mental retardation in children. With the...