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DOCK–PET: database of CNS kinetic parameters in the healthy human brain for existing PET tracers
PurposeInformation about developed positron emission tomography (PET) tracers and obtained clinical PET images is publicly available in a database....
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Preliminary Evaluation of 18F-Labeled Benzylguanidine Analogs as NET Tracers for Myocardial Infarction Diagnosis
PurposeHeart failure (HF) remains a major cause of late morbidity and mortality after myocardial infarction (MI). To date, no clinically established 18...
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Emerging PET Tracers in Cardiac Molecular Imaging
18 F-fluorodeoxyglucose (FDG) and 18 F-sodium fluoride (NaF) represent emerging PET tracers used to assess atherosclerosis-related inflammation and...
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COVID-19 contact tracing at work in Belgium - how tracers tweak guidelines for the better
BackgroundWhen conducting COVID-19 contact tracing, pre-defined criteria allow differentiating high-risk contacts (HRC) from low-risk contacts (LRC)....
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Development and first-in-human study of PSMA-targeted PET tracers with improved pharmacokinetic properties
PurposeA series of new 68 Ga-labeled tracers based on [ 68 Ga]Ga-PSMA-617 were developed to augment the tumor-to-kidney ratio and reduce the activity...
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Toward standardization of tau PET imaging corresponding to various tau PET tracers: a multicenter phantom study
ObjectiveTau positron emission tomography (PET) imaging is a recently developed non-invasive tool that can detect the density and extension of tau...
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Potential PET tracers for imaging of tumor-associated macrophages
The increasing incidence of cancer over the years is one of the most challenging problems in healthcare. As cancer progresses, the recruitment of...
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Synthesis and preclinical evaluation of novel 18F-vancomycin-based tracers for the detection of bacterial infections using positron emission tomography
IntroductionBacterial infections are a major problem in medicine, and the rapid and accurate detection of such infections is essential for optimal...
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Advances in positron emission tomography tracers related to vascular calcification
Microcalcification, a type of vascular calcification, increases the instability of plaque and easily leads to acute clinical events. Positron...
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ImmunoPET imaging of Trop2 expression in solid tumors with nanobody tracers
PurposeThe high expression of the transmembrane glycoprotein trophoblast cell-surface antigen 2 (Trop2) was strongly associated with the progression...
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Brain perfusion estimation by Tikhonov model-free deconvolution in a long axial field of view PET/CT scanner exploring five different PET tracers
PurposeNew total-body PET scanners with a long axial field of view (LAFOV) allow for higher temporal resolution due to higher sensitivity, which...
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Discriminative binding of tau PET tracers PI2620, MK6240 and RO948 in Alzheimer’s disease, corticobasal degeneration and progressive supranuclear palsy brains
Recent mechanistic and structural studies have challenged the classical tauopathy classification approach and revealed the complexity and...
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The evidence-based role of catecholaminergic PET tracers in Neuroblastoma. A systematic review and a head-to-head comparison with mIBG scintigraphy
BackgroundMolecular imaging is pivotal in staging and response assessment of children with neuroblastoma (NB). [ 123 I]-metaiodobenzylguanidine (mIBG)...
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Validation of image-derived input function using a long axial field of view PET/CT scanner for two different tracers
BackgroundAccurate image-derived input function (IDIF) from highly sensitive large axial field of view (LAFOV) PET/CT scanners could avoid the need...
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Comparison of the Safety and Thoroughness of Preoperative Versus Intraoperative Injection of Nanocarbon Tracers in Thyroid Cancer Surgery
This study aimed to compare the safety and thoroughness of preoperative versus intraoperative injections of nanocarbon tracers into the thyroid gland...
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The Homunculus of unspecific bone uptakes associated with PSMA-targeted tracers: a systematic review-based definition
PurposeProstate-Specific Membrane Antigen (PSMA)-targeted Positron Emission Tomography (PET) has revolutionised prostate cancer (PCa) diagnosis and...
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PET Tracers for Imaging Cardiac Function in Cardio-oncology
Purpose of ReviewSuccessful treatment of cancer can be hampered by the attendant risk of cardiotoxicity, manifesting as cardiomyopathy, left...
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18F-labeled tracers targeting fibroblast activation protein
BackgroundCancer-associated fibroblasts are found in the stroma of epithelial tumors. They are characterized by overexpression of the fibroblast...
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Advancements in theranostic applications: exploring the role of fibroblast activation protein inhibition tracers in enhancing thyroid health assessment
BackgroundThe diagnostic accuracy of [ 18 F]-fluorodeoxyglucose ([ 18 F]-FDG) positron emission tomography imaging in accurately identifying thyroid...