Search
Search Results
-
Mechanisms of initiation of cortical spreading depression
BackgroundThere is increasing evidence from human and animal studies that cortical spreading depression (CSD) is the neurophysiological correlate of...
-
The Role of Astrocytes in Migraine with Cortical Spreading Depression: Protagonists or Bystanders? A Narrative Review
Cortical spreading depression (CSD) is a slow wave of cortical depolarization closely associated with migraines with an aura. Previously, it was...
-
Estrogen modulation of cortical spreading depression
Background and aimsCortical spreading depression (CSD), a transient neuronal and glial depolarization that propagates slowly across the cerebral...
-
Cortical spreading depression induces propagating activation of the thalamus ventral posteromedial nucleus in awake mice
BackgroundAs the relay centre for processing sensory information, the thalamus may involve in the abnormal sensory procedure caused by cortical...
-
Different vulnerability of fast and slow cortical oscillations to suppressive effect of spreading depolarization: state-dependent features potentially relevant to pathogenesis of migraine aura
BackgroundSpreading depolarization (SD), underlying mechanism of migraine aura and potential activator of pain pathways, is known to elicit transient...
-
The effect of sex and estrus cycle stage on optogenetic spreading depression induced migraine-like pain phenotypes
BackgroundMigraine is more prevalent in females, raising the possibility that sex and gonadal hormones modulate migraine. We recently demonstrated...
-
From spreading depolarization to blood–brain barrier dysfunction: navigating traumatic brain injury for novel diagnosis and therapy
Considerable strides in medical interventions during the acute phase of traumatic brain injury (TBI) have brought improved overall survival rates....
-
Cortical spreading depression can be triggered by sensory stimulation in primed wild type mouse brain: a mechanistic insight to migraine aura generation
BackgroundUnlike the spontaneously appearing aura in migraineurs, experimentally, cortical spreading depression (CSD), the neurophysiological...
-
Efficacy profile of noninvasive vagus nerve stimulation on cortical spreading depression susceptibility and the tissue response in a rat model
BackgroundNoninvasive vagus nerve stimulation (nVNS) has recently emerged as a promising therapy for migraine. We previously demonstrated that vagus...
-
Relationship between attitudes toward COVID-19 infection, depression and anxiety: a cross-sectional survey in Japan
BackgroundAlthough negative attitudes are known to develop with experiences of COVID-19 infection, it remains unclear whether such attitudes...
-
Src family kinases activity is required for transmitting purinergic P2X7 receptor signaling in cortical spreading depression and neuroinflammation
BackgroundPurinergic P2X7 receptor plays an important role in migraine pathophysiology. Yet precise molecular mechanism underlying P2X7R signaling in...
-
Noninvasive and reliable automated detection of spreading depolarization in severe traumatic brain injury using scalp EEG
BackgroundSpreading depolarizations (SDs) are a biomarker and a potentially treatable mechanism of worsening brain injury after traumatic brain...
-
Anxiety and depression among COVID-19 survivors: a cross-sectional study
BackgroundThe novel coronavirus disease (COVID-19) outbreak has spread globally and resulted in physical suffering in addition to its negative...
-
COVID and depression among stratified population groups: a narrative review
The Covid-19 pandemic has impacted and infiltrated every aspect of our lives. Successive lockdowns, social distancing measures, and reduction in...
-
Brain regions susceptible to alpha-synuclein spreading
The spreading of misfolded alpha-synuclein (α-syn) protein has been observed in animal models of Parkinson’s disease (PD) and other...
-
Interpersonal Factors, Peer Relationship Stressors, and Gender Differences in Adolescent Depression
Purpose of ReviewCompared to boys, girls value close relationships more. Thus, heightened affiliative proclivities may serve as a particularly...
-
Social distancing stress, anxiety/depression, COVID-19 diagnosis, gender identity, and immigration status
BackgroundStrict social distancing public health measures to decrease COVID-19 spread increased social distancing stress. However, differences in...
-
Microglia Modulate Cortical Spreading Depolarizations After Ischemic Stroke: A Narrative Review
Cortical spreading depolarizations (CSDs) are characterized by waves of diminished electroencephalography activity that propagate across the cortex...
-
Suicidal Risk and Depression in Pregnant Women in Times of Pandemic
PurposePregnancy is a risk period for the development of mental disorders. About 10% of pregnant women worldwide experience a mental disorder, mainly...
