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In vitro platform to model the function of ionocytes in the human airway epithelium
BackgroundPulmonary ionocytes have been identified in the airway epithelium as a small population of ion transporting cells expressing high levels of
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A rare case of asymptomatic giant pulmonary hamartoma
BackgroundPulmonary hamartomas are benign lung lesions. Histopathologically, pulmonary hamartoma is composed of varying amounts of mesenchymal...
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Giant retinal pigment epithelium tears with membranous nephropathy: a case report and literature review
BackgroundKidney and eye diseases may be closely linked. Tears of the retinal pigment epithelium (RPE) have been reported to be related to kidney...
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Pathological findings of pulmonary papillary adenoma with EGFR mutation and literature review: two cases report
ObjectivePulmonary papillary adenoma is an extremely rare benign tumor. It is derived from type II lung cells and club cells, suggesting that it may...
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Pulmonary placental transmogrification: a difficult pattern in differential diagnosis of pulmonary hamartomas from a tertiary care hospital in Turkey
ObjectivePulmonary placental transmogrification (PT) is a benign lesion curable by resection, represented by an unusual peculiar morphological...
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Pursuing Clinical Predictors and Biomarkers for Progression in ILD: Analysis of the Pulmonary Fibrosis Foundation (PFF) Registry
IntroductionPulmonary fibrosis is a characteristic of various interstitial lung diseases (ILDs) with differing etiologies. Clinical trials in...
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SIgA in various pulmonary diseases
Secretory immunoglobulin A (SIgA) is one of the most abundant immunoglobulin subtypes among mucosa, which plays an indispensable role in the...
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Tobacco and menthol flavored nicotine-free electronic cigarettes induced inflammation and dysregulated repair in lung fibroblast and epithelium
BackgroundElectronic cigarette (e-cig) va** has increased in the past decade in the US, and e-cig use is misleadingly marketed as a safe cessation...
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Family with sequence similarity 13 member A mediates TGF-β1-induced EMT in small airway epithelium of patients with chronic obstructive pulmonary disease
BackgroundTo explore the role of family with sequence similarity 13 member A (FAM13A) in TGF-β1-induced EMT in the small airway epithelium of...
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Cyclophilin D Contributes to Airway Epithelial Mitochondrial Damage in Chronic Obstructive Pulmonary Disease
IntroductionAirway epithelial mitochondrial injury is an important pathogenesis of chronic obstructive pulmonary disease (COPD). Cyclophilin D (CypD)...
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Lung transcriptomics reveals the underlying mechanism by which aerobic training enhances pulmonary function in chronic obstructive pulmonary disease
BackgroundAerobic training is the primary method of rehabilitation for improving respiratory function in patients with chronic obstructive pulmonary...
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Emerging Roles of Galectin-3 in Pulmonary Diseases
Galectin-3 is a multifunctional protein that is involved in various physiological and pathological events. Emerging evidence suggests that galectin-3...
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Characterization of pulmonary vascular remodeling and MicroRNA-126-targets in COPD-pulmonary hypertension
BackgroundDespite causing increased morbidity and mortality, pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD) patients...
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Pulmonary salivary gland tumor–hyalinizing clear cell carcinoma: a literature review
Primary pulmonary hyalinizing clear cell carcinoma (HCCC) is a very rare lung tumor that accounts for less than 0.09% of all primary lung tumors and...
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Stepwise diagnostic algorithm for high-attenuation pulmonary abnormalities on CT
High-attenuation pulmonary abnormalities are commonly seen on CT. These findings are increasingly encountered with the growing number of CT...
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Typical carcinoid in right middle lobe of pulmonary hypoplasia
BackgroundPulmonary typical carcinoid occurring in hypoplasia of the right middle lobe is very rare.
Case presentationA routine examination's chest...
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Multiplexed analysis of macrophage polarisation in pulmonary metastases of microsatellite stable colorectal cancer
Tumour-associated macrophages (TAMs) express a continuum of phenotypes ranging from an anti-tumoural M1-like phenotype to a pro-tumoural M2-like...
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Molecular Mechanisms Underlying Systemic Sclerosis–Associated Interstitial Lung Disease and Idiopathic Pulmonary Fibrosis: an Update
Purpose of reviewSystemic sclerosis–associated interstitial lung disease (SSc-ILD) and idiopathic pulmonary fibrosis (IPF) are fatal fibrotic lung...
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Spatially distinct molecular patterns of gene expression in idiopathic pulmonary fibrosis
BackgroundIdiopathic pulmonary fibrosis (IPF) is a heterogeneous disease that is pathologically characterized by areas of normal-appearing lung...
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Effects of long-acting muscarinic antagonists on promoting ciliary function in airway epithelium
BackgroundMucociliary clearance (MCC) is an essential defense mechanism in airway epithelia for removing pathogens from the respiratory tract....
