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Anesthesia, Anesthetics, and Postoperative Cognitive Dysfunction in Elderly Patients
Postoperative cognitive dysfunction (POCD) remains a major issue that worsens the prognosis of elderly surgery patients. This article reviews the...
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Postoperative cognitive dysfunction: a concept analysis
BackgroundPost-operative cognitive dysfunction (POCD) is a concern for clinicians that often presents post-surgery where generalized anesthesia has...
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Intravenous infusion of dexmedetomidine during the surgery to prevent postoperative delirium and postoperative cognitive dysfunction undergoing non-cardiac surgery: a meta-analysis of randomized controlled trials
BackgroundDexmedetomidine plays a pivotal role in mitigating postoperative delirium and cognitive dysfunction while enhancing the overall quality of...
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The role of dexmedetomidine administered via intravenous infusion as adjunctive therapy to mitigate postoperative delirium and postoperative cognitive dysfunction in elderly patients undergoing regional anesthesia: a meta-analysis of randomized controlled trials
Study objectiveThis meta-analysis aimed to assess whether continuous intravenous administration of DEX during surgery can be part of the measures to...
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The effect of intravenous lidocaine on postoperative cognitive dysfunction: a systematic review and meta-analysis
BackgroundPostoperative cognitive dysfunction (POCD) has been reported as a significant complication in elderly patients. Various methods have been...
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Risk factors for postoperative cognitive dysfunction in elderly patients undergoing surgery for oral malignancies
We aimed to analyse postoperative cognitive dysfunction (POCD) incidence and risk factors in elderly adults who underwent surgery for oral...
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Effect of dexmedetomidine on postoperative cognitive dysfunction in elderly patients undergoing orthopaedic surgery: study protocol for a randomized controlled trial
AimsThis trial aims to assess whether dexmedetomidine can reduce the incidence of postoperative cognitive dysfunction in elderly orthopaedic patients...
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Effect of remote ischemic preconditioning on postoperative cognitive dysfunction in adult patients with general anesthesia: a meta-analysis
BackgroundRemote ischemic preconditioning (RIPC) is proven to have neuroprotective protective effects. Nevertheless, the impact of RIPC on...
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The risk factors of postoperative cognitive dysfunction in patients undergoing carotid endarterectomy: an updated meta-analysis
ObjectiveThe purpose of the current meta-analysis was to determine the incidence and risk factors to provide a scientific basis for prevention and...
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Postoperative cognitive dysfunction after beach chair positioning compared to supine position in orthopaedic surgery in the elderly
IntroductionPostoperative cognitive dysfunction (POCD) occurs in up to 26% of patients older than 60 years 1 week after non-cardiac surgery....
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Protective effect of intranasal insulin on postoperative cognitive dysfunction in elderly patients with metabolic syndrome undergoing noncardiac surgery: a randomized clinical trial
BackgroundInsulin plays a crucial and multifactorial role in cognitive activity, with insulin resistance appearing in neurodegenerative and metabolic...
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Irreversible postoperative cognitive impairment after unruptured intracranial aneurysm treatment in the elderly
PurposePostoperative cognitive dysfunction and recovery remain unclear in older patients undergoing interventional therapies for unruptured...
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Efficiency of probiotics in elderly patients undergoing orthopedic surgery for postoperative cognitive dysfunction: a study protocol for a multicenter, randomized controlled trial
BackgroundPostoperative cognitive dysfunction (POCD) refers to a neurological dysfunction after a major surgery and anesthesia. It is common in...
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A risk prediction model based on machine learning for postoperative cognitive dysfunction in elderly patients with non-cardiac surgery
BackgroundEarly identification of elderly patients undergoing non-cardiac surgery who may be at high risk for postoperative cognitive dysfunction...
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Effects of regional cerebral oxygen saturation monitoring on postoperative cognitive dysfunction in older patients: a systematic review and meta-analysis
Background:Postoperative cognitive dysfunction (POCD) is common after surgery and anesthesia, particularly in older patients. It has been reported...
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Predictors of early postoperative cognitive dysfunction in middle-aged patients undergoing cardiac surgery: retrospective observational study
PurposeThis study aimed to identify the incidence and risk factors of early post-operative cognitive dysfunction (POCD) in middle-aged patients...
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Effects of conventional nursing in the operating room combined with transcutaneous electrical acupoint stimulation on postoperative cognitive dysfunction after total knee arthroplasty in elderly patients
BackgroundTo observe the effects of conventional theatre nursing combined with transcutaneous electrical acupoint stimulation (TEAS) on postoperative...
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Mechanisms of hypoxia in the hippocampal CA3 region in postoperative cognitive dysfunction after cardiopulmonary bypass
BackgroundPostoperative cognitive dysfunction (POCD) is a complication with high morbidity and mortality, commonly observed in the elderly who...
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Oxytocin attenuates hypothalamic injury-induced cognitive dysfunction by inhibiting hippocampal ERK signaling and Aβ deposition
In clinical settings, tumor compression, trauma, surgical injury, and other types of injury can cause hypothalamic damage, resulting in various types...
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Ginkgolide B improved postoperative cognitive dysfunction by inhibiting microgliosis-mediated neuroinflammation in the hippocampus of mice
BackgroundPostoperative cognitive dysfunction (POCD) are a common complication of the central nervous system following surgery and anesthesia. The...
