Search
Search Results
-
Acute Systemic Toxicity Caused by Topical Application of EMLA Cream on a Leg Ulcer: Case Report and Review of Literature
IntroductionSystemic toxicity of eutectic mixture of local anesthetics (EMLA) cream is rare and is most commonly observed in children, for example,...
-
Aclarubicin: contemporary insights into its mechanism of action, toxicity, pharmacokinetics, and clinical standing
Aclarubicin (aclacinomycin A) is one of the anthracycline antineoplastic antibiotics with a multifaceted mechanism of antitumor activity. As a...
-
Mitochondrial metabolism: a predictive biomarker of radiotherapy efficacy and toxicity
IntroductionRadiotherapy is a mainstay of cancer treatment. Clinical studies revealed a heterogenous response to radiotherapy, from a complete...
-
Oxygen supplementation in anesthesia can block FLASH effect and anti-tumor immunity in conventional proton therapy
BackgroundRadiation-induced neurocognitive dysfunction is a major adverse effect of brain radiation therapy and has specific relevance in pediatric...
-
The impact of hyperbaric oxygen therapy on late radiation toxicity and quality of life in breast cancer patients
PurposeTo evaluate symptoms of late radiation toxicity, side effects, and quality of life in breast cancer patients treated with hyperbaric oxygen...
-
Self-assembled peptide-dye nanostructures for in vivo tumor imaging and photodynamic toxicity
We report noncovalent assemblies of iRGD peptides and methylene blue dyes via electrostatic and hydrophobic stacking. These resulting nanomaterials...
-
Body composition measures as a determinant of Alpelisib related toxicity
BackgroundBody composition has emerged as an important prognostic factor in patients treated with cancer. Severe depletion of skeletal muscle,...
-
Chronic supplementation of noni in diabetic type 1-STZ rats: effects on glycemic levels, kidney toxicity and exercise performance
Noni is a fruit with potential medicinal use preventing elevated blood glucose levels in diabetes mellitus. Its effects have been attributed to an...
-
Ivabradine toxicity: a case report
BackgroundWe describe a case of symptomatic bradycardia resulting from ivabradine toxicity by measurement of ivabradine levels, of which there are...
-
SOX71, A Biocompatible Succinyl Derivative of the Triarylmethyl Radical OX071 for In Vivo Quantitative Oxygen Map** Using Electron Paramagnetic Resonance
PurposeThis study aimed to develop a biocompatible oximetric electron paramagnetic resonance (EPR) spin probe with reduced self-relaxation, and...
-
Interplay of hypoxia-inducible factors and oxygen therapy in cardiovascular medicine
Mammals have evolved to adapt to differences in oxygen availability. Although systemic oxygen homeostasis relies on respiratory and circulatory...
-
Using maximum plasma concentration (Cmax) to personalize taxane treatment and reduce toxicity
Taxanes are a widely used class of anticancer agents that play a vital role in the treatment of a variety of cancers. However, toxicity remains a...
-
Use of oxygen therapy for pneumocephalus: a systematic review
Pneumocephalus is the pathologic collection of air in the intracranial cavity. In sufficient volumes, it can contribute to symptoms ranging from...
-
A mechanistic consideration of oxygen enhancement ratio, oxygen transport and their relevancies for normal tissue sparing under FLASH irradiation
Our study investigated the role of oxygen in mediating the FLASH effect. This effect, which was first reported in vitro in the 1950s and in vivo in...
-
Differences in the characteristics and pulmonary toxicity of nano- and micron-sized respirable coal dust
BackgroundThe characteristics of coal dust (CD) particles affect the inhalation of CD, which causes coal worker’s pneumoconiosis (CWP). CD...
-
Determination of cefaclor antibiotic toxicity in zebrafish embryos
Cefaclor represents second-generation cephalosporin antibiotics that act by inhibiting bacterial cell wall synthesis. Systematic studies on the...
-
Role of Hyperbaric Oxygen in Filler-Induced Vascular Occlusion
IntroductionThe rising incidence of filler-induced vascular complications in the context of aesthetic procedures necessitates a thorough assessment...
-
Alpha-pinene neutralizes cisplatin-induced reproductive toxicity in male rats through activation of Nrf2 pathway
PurposeTesticular toxicity is one of the most important side effects of cisplatin (CP) therapy. Alpha-pinene (AP) is a naturally occurring...
-
Practice of oxygen use in anesthesiology – a survey of the European Society of Anaesthesiology and Intensive Care
BackgroundOxygen is one of the most commonly used drugs by anesthesiologists. The World Health Organization (WHO) gave recommendations regarding...
-
High arterial oxygen levels and supplemental oxygen administration in traumatic brain injury: insights from CENTER-TBI and OzENTER-TBI
PurposeThe effect of high arterial oxygen levels and supplemental oxygen administration on outcomes in traumatic brain injury (TBI) is debated, and...
