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Optimizing Care: Integrative Oncology in Myeloproliferative Neoplasm
Purpose of ReviewMyeloproliferative neoplasm (MPN) burdens the lives of those affected. MPN patients endure significant impacts on their physical,...
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Myelofibrosis-type megakaryocyte dysplasia (MTMD) as a distinct category of BCR::ABL-negative myeloproliferative neoplasms. Challenges and perspectives
In this Perspective , we discuss criteria for defining a new disease entity or variant of a recognized disease or disorder. We do so in the context of...
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International Consensus Classification of myeloid and lymphoid neoplasms: myeloproliferative neoplasms
The recently published International Consensus Classification (ICC) of myeloid neoplasms summarized the results of an in-depth effort by...
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Immunophenotype of myeloid granulocytes in Chinese patients with BCR::ABL1-negative myeloproliferative neoplasms
Typical BCR::ABL1-negative myeloproliferative neoplasms (MPN) are mainly referred to as polycythemia vera (PV), essential thrombocythemia (ET), and...
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A Journey Through JAK Inhibitors for the Treatment of Myeloproliferative Diseases
Purpose of ReviewChronic myeloproliferative neoplasms (MPN) represent a group of diseases characterised by constitutive activation of the JAK/STAT...
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In-Hospital and readmission outcomes of patients with myeloproliferative neoplasms and atrial fibrillation: insights from the National Readmissions Database
IntroductionPatients with myeloproliferative neoplasms (MPNs) and atrial fibrillation (AF) are at increased risk of thrombosis and bleeding. However,...
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Combined venous and arterial thrombosis revealing underlying myeloproliferative disorder in a young patient: a case report
BackgroundMyeloproliferative neoplasms (MPNs) such as polycythemia Vera (PV) and Essential Thrombocythemia (ET) can be associated with a high risk of...
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A review of current knowledge of myeloproliferative disorders in the horse
Myeloid disorders are conditions being characterized by abnormal proliferation and development of myeloid lineage including granulocytes...
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Molecular pathogenesis of the myeloproliferative neoplasms
The Philadelphia negative myeloproliferative neoplasms (MPN) compromise a heterogeneous group of clonal myeloid stem cell disorders comprising...
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Clinical clues for suspecting wild-type transthyretin cardiac amyloidosis in patients with monoclonal gammopathy of undetermined significance: a case report
BackgroundMyeloproliferative disorders, including monoclonal gammopathy of undetermined significance (MGUS), are often associated with amyloid...
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Unique features of vaccine-induced immune thrombotic thrombocytopenia; a new anti-platelet factor 4 antibody-mediated disorder
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a highly prothrombotic disorder caused by anti-PF4 antibodies that activate platelets...
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Combination of treosulfan, fludarabine and cytarabine as conditioning in patients with acute myeloid leukemia, myelodysplastic syndrome and myeloproliferative neoplasms
PurposeTreosulfan and fludarabine (Treo/Flu) were successfully introduced into toxicity-reduced conditioning for SCT. However, the risk of post-SCT...
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Multiple cardiac surgical procedures in a case of an octogenarian with essential thrombocythemia
BackgroundEssential thrombocythemia (ET) is a chronic myeloproliferative disorder characterized by an elevation of platelet counts with a tendency...
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Extramedullary hematopoiesis in an inguinal lymph node: an unusual presentation of primary myelofibrosis
BackgroundExtramedullary hematopoiesis (EMH) is a proliferation of hematopoietic tissue outside of the bone marrow medullary space. It is a...
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Myeloid/lymphoid neoplasm with eosinophilia and BCR/FGFR1 rearrangement with transformation to cortical T-lymphoblastic lymphoma and erythroid precursors: a case report
BackgroundMyeloproliferative neoplasms are a group of diseases with diverse biological and clinical characteristics. As a provisional separate...
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Fedratinib, a newly approved treatment for patients with myeloproliferative neoplasm-associated myelofibrosis
Myeloproliferative neoplasm (MPN)-associated myelofibrosis (MF) is characterized by cytopenias, marrow fibrosis, constitutional symptoms,...
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Biological drivers of clinical phenotype in myelofibrosis
Myelofibrosis (MF) is a myeloproliferative disorder that exhibits considerable biological and clinical heterogeneity. At the two ends of the disease...
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Atypical Megakaryocyte Morphology: an Important Diagnostic Clue for JAK2 Mutation–Associated Disorders
Chronic myeloproliferative neoplasm (MPN) is a diverse group of bone marrow disorders. These include BCR-ABL fusion gene–related disorders or...
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Progression, transformation, and unusual manifestations of myelodysplastic syndromes and myelodysplastic-myeloproliferative neoplasms: lessons learned from the XIV European Bone Marrow Working Group Course 2019
Disease progression in myelodysplastic syndromes (MDS) and myelodysplastic-myeloproliferative neoplasms (MDS/MPN) is a major source of mortality. The...
