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Lower ultra-short-term heart rate variability can predict worse mucosal healing in ulcerative colitis
BackgroundPsychological stress has been proved to be a risk factor for exacerbation for ulcerative colitis (UC). However, traditional approaches of...
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Mechanisms of mucosal healing: treating inflammatory bowel disease without immunosuppression?
Almost all currently available treatments for inflammatory bowel disease (IBD) act by inhibiting inflammation, often blocking specific inflammatory...
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A novel twin-grasper assisted mucosal inverted closure technique for closing large artificial gastric mucosal defects
BackgroundLarge artificial gastric mucosal defects are always left unclosed for natural healing due to technique difficulties in closure. This study...
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Mechanism of Acupuncture and Moxibustion on Promoting Mucosal Healing in Ulcerative Colitis
The latest guideline about ulcerative colitis (UC) clinical practice stresses that mucosal healing, rather than anti-inflammation, is the main target...
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Mucosal healing assessment in Crohn’s disease with normalized iodine concentration from dual-energy CT enterography: comparison with endoscopy
ObjectivesMucosal healing (MH) is an important goal in the treatment of patients with Crohn’s disease (CD). Noninvasive assessment of MH with...
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Correlation of mucosal healing endpoints with long-term clinical and patient-reported outcomes in ulcerative colitis
BackgroundWe evaluated the clinical relevance of achieving histologic endoscopic mucosal improvement (HEMI) and the more stringent target of...
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Evaluation of Mucosal Healing in Crohn’s Disease: Radiomics Models of Intestinal Wall and Mesenteric Fat Based on Dual-Energy CT
This study aims to assess the effectiveness of radiomics signatures obtained from dual-energy computed tomography enterography (DECTE) in the...
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Mucosal healing of small intestinal stricture is associated with improved prognosis post-dilation in Crohn’s disease
BackgroundSmall intestinal stricture is a major cause for surgery in Crohn’s disease (CD). Endoscopic balloon dilation (EBD) is performed for small...
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A Computational Platform Integrating a Mechanistic Model of Crohn’s Disease for Predicting Temporal Progression of Mucosal Damage and Healing
IntroductionPhysicians are often required to make treatment decisions for patients with Crohn’s disease on the basis of limited objective information...
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Combination of serological biomarkers and clinical features to predict mucosal healing in Crohn’s disease: a multicenter cohort study
PurposeMucosal healing (MH) has become the treatment goal of patients with Crohn’s disease (CD). This study aims to develop a noninvasive and...
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Simplified Histologic Mucosal Healing Scheme (SHMHS) for inflammatory bowel disease: a nationwide multicenter study of performance and applicability
BackgroundAssessment of mucosal healing is important for the management of patients with inflammatory bowel disease (IBD), but endoscopy can miss...
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Fecal calprotectin predicts endoscopic activity and mucosal healing of small bowel Crohn’s disease evaluated by double-balloon endoscopy
PurposeFecal calprotectin (FC) levels can reflect the level of intestinal inflammation. Crohn’s disease (CD), which affects the small bowel, has not...
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A novel clinical radiomics nomogram at baseline to predict mucosal healing in Crohn’s disease patients treated with infliximab
ObjectivesMucosal healing (MH) is currently the gold standard in Crohn’s disease (CD) management. Noninvasive assessment of MH in CD patients is...
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Mucosal vs. cutaneous advancement flaps for the treatment of chronic anal fissures: a randomized clinical trial
PurposeThe aim of this study was to compare two surgical treatment methods for chronic anal fissures (CAF), mucosal advancement flap anoplasty (MAFA)...
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Recombinant Platelet-Derived Growth Factor-BB (rhPDGF-BB) Augmented Collagen Grafting for Oral Mucosal Defect Reconstruction
ObjectiveTo assess the suitability of collagen grafting and compare the outcomes between rhPDGF-BB (recombinant human platelet-derived growth...
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A Retrospective Study on the Reconstruction of Nasal Septal Mucosal Defects after Asian Rhinoplasty
BackgroundNasal septal mucosal defects following rhinoplasty in Asian patients are uncommon complications. However, the reconstruction of such...
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Omeprazole taken once every other day can effectively prevent aspirin-induced gastrointestinal mucosal damage in rats
BackgroundProton-pump inhibitors (PPIs) prevent aspirin-associated gastric and duodenal mucosal damage. However, long-term use of PPIs can lead to...
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Apex Score: Predicting Flares in Small-Bowel Crohn’s Disease After Mucosal Healing
BackgroundOptimal strategies for using small-bowel capsule endoscopy (SBCE) in established small-bowel Crohn’s disease (CD) remain uncertain. Mucosal...
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Patient-Reported Outcome and Clinical Scores Are Equally Accurate in Predicting Mucosal Healing in Ulcerative Colitis: A Prospective Study
BackgroundOptimal management of patients with ulcerative colitis (UC) requires the accurate, objective assessment of disease activity.
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