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Increased Expression of Inactive Rhomboid Protein 2 in Circulating Monocytes after Acute Myocardial Infarction
Increased TNF-α levels following acute myocardial infarction (AMI) contribute to impaired recovery of myocardial function. Interaction of inactive...
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Intermittent fasting alleviates IMQ-induced psoriasis-like dermatitis via reduced γδT17 and monocytes in mice
AbstractPsoriasis is a chronic immune mediated inflammatory skin disease with systemic manifestations. It has been reported that caloric restriction...
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Role of monocytes and dendritic cells in cardiac reverse remodelling after cardiac resynchronization therapy
Background and aimsMonocytes and dendritic cells (DC) are both key inflammatory cells, with recognized effects on cardiac repair. However, there are...
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Neutrophil extracellular trap-induced intermediate monocytes trigger macrophage activation syndrome in adult-onset Still’s disease
BackgroundAdult-onset Still’s disease (AOSD) is a systemic autoinflammatory disease characterized by innate immune system activation, with a high...
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T-cell Immunoglobulin and Mucin Domain 3 in Circulating Monocytes as a Novel Biomarker for Coronary Artery Disease
The diagnostic role of T-cell immunoglobulin and mucin domain 3 (Tim-3) expression levels in circulating monocytes in coronary artery disease (CAD)...
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Contributions of bone marrow monocytes/macrophages in myeloproliferative neoplasms with JAK2V617F mutation
The classic BCR-ABL1-negative myeloproliferative neoplasm (MPN) is a highly heterogeneous hematologic tumor that includes three subtypes, namely...
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Targeting transitioning lung monocytes/macrophages as treatment strategies in lung disease related to environmental exposures
BackgroundEnvironmental/occupational exposures cause significant lung diseases. Agricultural organic dust extracts (ODE) and bacterial component...
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Differential immunophenotype of circulating monocytes from pregnant women in response to viral ligands
BackgroundViral infections during pregnancy can have deleterious effects on mothers and their offspring. Monocytes participate in the maternal host...
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CCR2-positive monocytes contribute to the pathogenesis of early diabetic retinopathy in mice
Aims/hypothesisAccumulating evidence suggests that leucocytes play a critical role in diabetes-induced vascular lesions and other abnormalities that...
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Mediating role of chiro-inositol metabolites on the effects of HLA-DR-expressing CD14 + monocytes in inflammatory bowel disease
BackgroundInflammatory bowel disease (IBD), a chronic inflammatory condition, is caused by several factors involving aberrant immune responses....
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Decreased expression of TIGIT on CD14 + monocytes correlates with clinical features and laboratory parameters of patients with primary Sjögren’s syndrome
ObjectivesThe purpose of this study was to investigate the expression of T-cell immunoglobulin and ITIM domain (TIGIT) in peripheral circulation of...
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Change of monocytes/macrophages in ulcerative colitis patients with symptoms of anxiety and depression
Background and aimsMonocytes/macrophages play important roles in inflammatory bowel disease and depression, but few studies had focused on the change...
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Genetic landscape and immune mechanism of monocytes associated with the progression of acute-on-chronic liver failure
ObjectiveAcute-on-chronic liver failure (ACLF) has a high prevalence and short-term mortality. Monocytes play an important role in the development of...
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Severe neurological impairment and immune function: altered neutrophils, monocytes, T lymphocytes, and inflammasome activation
BackgroundInfections cause significant morbidity and mortality in children with Severe Neurological Impairment (SNI). Alterations in immune cell...
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Dysregulation of long non-coding RNA gene expression pathways in monocytes of type 2 diabetes patients with cardiovascular disease
BackgroundMonocytes play a central role in the pathophysiology of cardiovascular complications in type 2 diabetes (T2D) patients through different...
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ZC3H4 regulates infiltrating monocytes, attenuating pulmonary fibrosis through IL-10
Silicosis is a pulmonary fibrosis-associated disease caused by the inhalation of large amounts of free silicon dioxide (SiO 2 ) that mainly manifests...
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Intermediate monocytes expansion and homing markers expression in COVID-19 patients associate with kidney dysfunction
Patients with severe SARS-CoV-2 infection have an overwhelming inflammatory response characterized by remarkable organs monocyte infiltration. We...
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Immunophenotypic changes of monocytes in myelodysplastic syndrome and clinical significance
BackgroundMyelodysplastic syndrome (MDS) is a type of heterogeneous myeloid clonal disorder usually diagnosed based on a combination of multiple...
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Cervical carcinoma induces NLRP3 inflammasome activation and IL-1ß release in human peripheral blood monocytes affecting patients’ overall survival
PurposeOur group previously demonstrated that genetic variants in inflammasome genes contribute to protection against the establishment of human...
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Monocytes subsets altered distribution and dysregulated plasma hsa-miR-21-5p and hsa-miR-155-5p in HCV-linked liver cirrhosis progression to hepatocellular carcinoma
PurposeThe authors aim to investigate the altered monocytes subsets distribution in liver cirrhosis (LC) and subsequent hepatocellular carcinoma...