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  1. Increased Expression of Inactive Rhomboid Protein 2 in Circulating Monocytes after Acute Myocardial Infarction

    Increased TNF-α levels following acute myocardial infarction (AMI) contribute to impaired recovery of myocardial function. Interaction of inactive...

    Phillip van Dijck, Carmen Hannemann, ... Bernd Hewing in Journal of Cardiovascular Translational Research
    Article Open access 14 May 2024
  2. Intermittent fasting alleviates IMQ-induced psoriasis-like dermatitis via reduced γδT17 and monocytes in mice

    Abstract

    Psoriasis is a chronic immune mediated inflammatory skin disease with systemic manifestations. It has been reported that caloric restriction...

    **angming Chen, Cheng Fu, ... Erxia Shen in Archives of Dermatological Research
    Article 17 May 2024
  3. Role of monocytes and dendritic cells in cardiac reverse remodelling after cardiac resynchronization therapy

    Background and aims

    Monocytes and dendritic cells (DC) are both key inflammatory cells, with recognized effects on cardiac repair. However, there are...

    Sílvia Martins, Natália António, ... Artur Paiva in BMC Cardiovascular Disorders
    Article Open access 15 November 2023
  4. Neutrophil extracellular trap-induced intermediate monocytes trigger macrophage activation syndrome in adult-onset Still’s disease

    Background

    Adult-onset Still’s disease (AOSD) is a systemic autoinflammatory disease characterized by innate immune system activation, with a high...

    **chao Jia, Mengyan Wang, ... Qiongyi Hu in BMC Medicine
    Article Open access 20 December 2023
  5. T-cell Immunoglobulin and Mucin Domain 3 in Circulating Monocytes as a Novel Biomarker for Coronary Artery Disease

    The diagnostic role of T-cell immunoglobulin and mucin domain 3 (Tim-3) expression levels in circulating monocytes in coronary artery disease (CAD)...

    Fang** **ao, Zhiqiang Jia, ... Mei Hong in Journal of Cardiovascular Translational Research
    Article 07 December 2023
  6. Contributions of bone marrow monocytes/macrophages in myeloproliferative neoplasms with JAK2V617F mutation

    The classic BCR-ABL1-negative myeloproliferative neoplasm (MPN) is a highly heterogeneous hematologic tumor that includes three subtypes, namely...

    Wenjuan Fan, Weijie Cao, ... Wang Ma in Annals of Hematology
    Article 26 May 2023
  7. Targeting transitioning lung monocytes/macrophages as treatment strategies in lung disease related to environmental exposures

    Background

    Environmental/occupational exposures cause significant lung diseases. Agricultural organic dust extracts (ODE) and bacterial component...

    Aaron D. Schwab, Todd A. Wyatt, ... Jill A. Poole in Respiratory Research
    Article Open access 09 April 2024
  8. Differential immunophenotype of circulating monocytes from pregnant women in response to viral ligands

    Background

    Viral infections during pregnancy can have deleterious effects on mothers and their offspring. Monocytes participate in the maternal host...

    Marcelo Farias-Jofre, Roberto Romero, ... Nardhy Gomez-Lopez in BMC Pregnancy and Childbirth
    Article Open access 06 May 2023
  9. CCR2-positive monocytes contribute to the pathogenesis of early diabetic retinopathy in mice

    Aims/hypothesis

    Accumulating evidence suggests that leucocytes play a critical role in diabetes-induced vascular lesions and other abnormalities that...

    Aicha Saadane, Alexander A. Veenstra, ... Timothy S. Kern in Diabetologia
    Article Open access 26 January 2023
  10. Mediating role of chiro-inositol metabolites on the effects of HLA-DR-expressing CD14 + monocytes in inflammatory bowel disease

    Background

    Inflammatory bowel disease (IBD), a chronic inflammatory condition, is caused by several factors involving aberrant immune responses....

    Leichang Zhang, Pan Shen, ... **aojun Yan in BMC Gastroenterology
    Article Open access 17 June 2024
  11. Decreased expression of TIGIT on CD14 + monocytes correlates with clinical features and laboratory parameters of patients with primary Sjögren’s syndrome

    Objectives

    The purpose of this study was to investigate the expression of T-cell immunoglobulin and ITIM domain (TIGIT) in peripheral circulation of...

    ** Zhao, Cheng Peng, ... Jian Wu in Clinical Rheumatology
    Article 25 September 2023
  12. Change of monocytes/macrophages in ulcerative colitis patients with symptoms of anxiety and depression

    Background and aims

    Monocytes/macrophages play important roles in inflammatory bowel disease and depression, but few studies had focused on the change...

    **n Gao, Shihao Duan, ... Yan Zhang in BMC Gastroenterology
    Article Open access 11 March 2023
  13. Genetic landscape and immune mechanism of monocytes associated with the progression of acute-on-chronic liver failure

    Objective

    Acute-on-chronic liver failure (ACLF) has a high prevalence and short-term mortality. Monocytes play an important role in the development of...

    Jia Yao, Tian Liu, ... Jun Xu in Hepatology International
    Article Open access 10 January 2023
  14. Severe neurological impairment and immune function: altered neutrophils, monocytes, T lymphocytes, and inflammasome activation

    Background

    Infections cause significant morbidity and mortality in children with Severe Neurological Impairment (SNI). Alterations in immune cell...

    John Allen, Johana Isaza-Correa, ... Eleanor J. Molloy in Pediatric Research
    Article Open access 17 January 2024
  15. Dysregulation of long non-coding RNA gene expression pathways in monocytes of type 2 diabetes patients with cardiovascular disease

    Background

    Monocytes play a central role in the pathophysiology of cardiovascular complications in type 2 diabetes (T2D) patients through different...

    Najeeb Halabi, Binitha Thomas, ... Charbel Abi Khalil in Cardiovascular Diabetology
    Article Open access 07 June 2024
  16. ZC3H4 regulates infiltrating monocytes, attenuating pulmonary fibrosis through IL-10

    Silicosis is a pulmonary fibrosis-associated disease caused by the inhalation of large amounts of free silicon dioxide (SiO 2 ) that mainly manifests...

    Ya** Liu, **nxin Zhang, ... Jie Chao in Respiratory Research
    Article Open access 12 August 2022
  17. Intermediate monocytes expansion and homing markers expression in COVID-19 patients associate with kidney dysfunction

    Patients with severe SARS-CoV-2 infection have an overwhelming inflammatory response characterized by remarkable organs monocyte infiltration. We...

    Chiara Dentone, Daniela Fenoglio, ... Gilberto Filaci in Clinical and Experimental Medicine
    Article 13 November 2022
  18. Immunophenotypic changes of monocytes in myelodysplastic syndrome and clinical significance

    Background

    Myelodysplastic syndrome (MDS) is a type of heterogeneous myeloid clonal disorder usually diagnosed based on a combination of multiple...

    Lijuan Li, Shunjie Yu, ... Rong Fu in Clinical and Experimental Medicine
    Article 02 August 2022
  19. Cervical carcinoma induces NLRP3 inflammasome activation and IL-1ß release in human peripheral blood monocytes affecting patients’ overall survival

    Purpose

    Our group previously demonstrated that genetic variants in inflammasome genes contribute to protection against the establishment of human...

    Fernanda Pereira Fernandes, Raylane Adrielle Gonçalves Cambui, ... Alessandra Pontillo in Clinical and Translational Oncology
    Article 16 June 2023
  20. Monocytes subsets altered distribution and dysregulated plasma hsa-miR-21-5p and hsa-miR-155-5p in HCV-linked liver cirrhosis progression to hepatocellular carcinoma

    Purpose

    The authors aim to investigate the altered monocytes subsets distribution in liver cirrhosis (LC) and subsequent hepatocellular carcinoma...

    Reham Hammad, Mona A. Eldosoky, ... Nadia M. Hamdy in Journal of Cancer Research and Clinical Oncology
    Article Open access 28 August 2023
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