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Molecular Imaging and Targeted Therapy Radiopharmaceuticals and Clinical Applications
This book, now published in its second edition, covers a wide range of topics relating to the use of radiopharmaceuticals. The basics of nuclear...
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Molecular-targeted therapy for childhood low-grade glial and glioneuronal tumors
Since the discovery of the association between BRAF mutations and fusions in the development of childhood low-grade gliomas and the subsequent...
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Molecular and functional imaging in cancer-targeted therapy: current applications and future directions
Targeted anticancer drugs block cancer cell growth by interfering with specific signaling pathways vital to carcinogenesis and tumor growth rather...
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Advances in molecular targeted therapies to increase efficacy of (chemo)radiation therapy
Recent advances in understanding the tumor’s biology in line with a constantly growing number of innovative technologies have prompted...
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A case of surgical treatment for recurrence of right ventricular metastasis due to renal cell carcinoma after molecular targeted therapy
BackgroundCardiac metastasis including the right ventricle from renal cell carcinoma is rare. No standard treatment for cardiac metastasis and...
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Advances in the molecular mechanism and targeted therapy of radioactive-iodine refractory differentiated thyroid cancer
Most patients with differentiated thyroid cancer have a good prognosis after radioactive iodine-131 treatment, but there are still a small number of...
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Liquid biopsy guides successful molecular targeted therapy of an inoperable pediatric brainstem neoplasm
Midline CNS tumors are occasionally inaccessible for surgical biopsies. In these instances, cell-free DNA (cfDNA) may serve as a viable alternative...
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Delayed pharyngocutaneous fistula caused by molecular targeted therapy: a case report
BackgroundMolecular-targeted agents used as a treatment for cancer can cause some rare and serious adverse events such as, delayed wound healing....
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Effectiveness and tolerability of camrelizumab combined with molecular targeted therapy for patients with unresectable or advanced HCC
There is a lack of effective programmed cell death protein 1 (PD-1)‐targeted immunotherapy with good tolerability in patients with advanced...
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Targeted therapy for osteosarcoma: a review
BackgroundOsteosarcoma is a common primary malignant tumour of the bone that usually occurs in children and adolescents. It is characterised by...
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Molecular Profiling and Targeted Therapies in Gliomas
Purpose of ReviewMolecular profiling enables the evaluation of genetic alterations for the diagnosis and classification of gliomas and the selection...
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Molecular perspective on targeted therapy in breast cancer: a review of current status
Breast cancer is categorized at the molecular level according to the status of certain hormone and growth factor receptors, and this classification...
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Treatment of node-positive endometrial cancer: chemotherapy, radiation, immunotherapy, and targeted therapy
The standard of treatment for node-positive endometrial cancer (FIGO Stage IIIC) in North America has been systemic therapy with or without...
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Targeted therapy and immunotherapy for T cell acute lymphoblastic leukemia/lymphoma
T cell acute lymphoblastic leukemia/lymphoma (T-ALL/LBL) is an aggressive malignancy of progenitor T cells. Despite significant improvements in...
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Research trends of targeted therapy for cholangiocarcinoma from 2003 to 2022: a bibliometric and visual analysis
In the past 20 years, targeted therapy for cholangiocarcinoma has attracted certain attention. There is a significant upward in papers focusing on...
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Tumor biomarkers for diagnosis, prognosis and targeted therapy
Tumor biomarkers, the substances which are produced by tumors or the body’s responses to tumors during tumorigenesis and progression, have been...
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Targeted therapy, immunotherapy, and chemotherapy for chordoma
Chordoma is a rare bone tumor often present in the skull base and spine. In addition, it is not sensitive to radiotherapy that surgical resection is...
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Molecular diagnostics tailoring personalized cancer therapy—an oncologist’s view
Medical oncology is rapidly evolving with the implementation of personalized, targeted therapies. Advances in molecular diagnostics and the biologic...
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Changes in Real-World Outcomes in Patients with Metastatic Renal Cell Carcinoma from the Molecular-Targeted Therapy Era to the Immune Checkpoint Inhibitor Era
BackgroundKnowledge of changes in the outcome in patients with metastatic renal cell carcinoma from the molecular-targeted therapy era to the immune...
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A multi-institutional study to predict the benefits of DEB-TACE and molecular targeted agent sequential therapy in unresectable hepatocellular carcinoma using a radiological-clinical nomogram
ObjectiveExploring the efficacy of a Radiological-Clinical (Rad-Clinical) model in predicting prognosis of unresectable hepatocellular carcinoma...
