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Evaluation of Diagnostic Significance of Salivary miRNA-184 and miRNA-21 in Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders
BackgroundAltered levels of miRNAs might affect the pathogenesis of oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders...
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Association analysis of miRNA-146a and miRNA-499 polymorphisms with rheumatoid arthritis: a case–control and trio-family study
Single nucleotide polymorphism is known to alter the expression and processing of miRNAs leading to a variety of diseases including rheumatoid...
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MiRNA-202 Role in Reproductive System and Gynecological Cancers
IntroductionMicroRNAs, also known as miRNAs, are small regulatory RNAs, and they also include many different types in terms of size and commission...
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Laryngeal cancer diagnosis via miRNA-based decision tree model
PurposeLaryngeal cancer (LC) is the most common head and neck cancer, which often goes undiagnosed due to the inaccessible nature of current...
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Regulation of adipogenesis by exosomal milk miRNA
Milk is a rich source of miRNA packaged in exosomes. Evidence for the systemic uptake and tissue distribution of milk exosomes was reported in...
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The DNA-repair protein APE1 participates with hnRNPA2B1 to motif-enriched and prognostic miRNA secretion
The base excision repair (BER) Apurinic/apyrimidinic endonuclease 1 (APE1) enzyme is endowed with several non-repair activities including miRNAs...
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Identification of a circulating three-miRNA panel for the diagnosis of primary open angle glaucoma
PurposeConventional diagnosis of primary open angle glaucoma (POAG) needs a combination of ophthalmic examinations. An efficient assay is urgently...
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Recent trends in miRNA therapeutics and the application of plant miRNA for prevention and treatment of human diseases
BackgroundResearchers now have a new avenue to investigate when it comes to miRNA-based therapeutics. miRNAs have the potential to be valuable...
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The role of miRNA-29b1, MMP-2, MMP-9 mRNAs, and proteins in early diagnosis of HCC
BackgroundHepatocellular carcinoma (HCC) is a common, serious malignancy with a dismal prognosis. As HCC is frequently missed in its early stages,...
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Unraveling the miRNA Puzzle in Atherosclerosis: Revolutionizing Diagnosis, Prognosis, and Therapeutic Approaches
Purpose of ReviewTo eradicate atherosclerotic diseases, novel biomarkers, and future therapy targets must reveal the burden of early atherosclerosis...
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A miRNA-based epigenetic molecular clock for biological skin-age prediction
Skin aging is one of the visible characteristics of the aging process in humans. In recent years, different biological clocks have been generated...
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Bioinformatics analysis of a disease-specific lncRNA–miRNA–mRNA regulatory network in recurrent spontaneous abortion (RSA)
BackgroundThis study investigated the molecular mechanisms of long non-coding RNAs (lncRNAs) in RSA using the lncRNA–miRNA–mRNA regulatory network.
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Targeting miRNA by CRISPR/Cas in cancer: advantages and challenges
Clustered regulatory interspaced short palindromic repeats (CRISPR) has changed biomedical research and provided entirely new models to analyze every...
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Ovarian Stimulation Altered Uterine Fluid Extracellular Vesicles miRNA Affecting Implantation in Rats
Uterine fluid (UF) extracellular vesicle (EV) miRNA may affect implantation and could be the potential biomarker of endometrial receptivity (ER)....
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Identifying miRNA biomarkers for breast cancer and ovarian cancer: a text mining perspective
BackgroundmicroRNA (miRNAs) are small, non-coding RNAs that mediate post-transcriptional gene silencing. Numerous studies have demonstrated the...
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Transcriptome sequencing and miRNA-mRNA network construction in exosome of macrophage M2 in stomach adenocarcinoma
BackgroundStomach adenocarcinoma (STAD) is the most common histological type of gastric cancer (GC). Macrophages are an essential part of the tumor...
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Milk miRNA expression in buffaloes as a potential biomarker for mastitis
BackgroundBuffaloes have the highest potential for production due to a promising gene pool that is being enhanced and upgraded. Mastitis is a...
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Characterization of the circulating transcriptome expression profile and identification of novel miRNA biomarkers in hypertrophic cardiomyopathy
BackgroundHypertrophic cardiomyopathy (HCM), one of the most common genetic cardiovascular diseases, but cannot be explained by single genetic...
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Extraction and identification of exosomes from three different sources of human ovarian granulosa cells and analysis of their differential miRNA expression profiles
ObjectiveAs important functional cells in the ovary, ovarian granulosa cells are involved in the regulation of oocyte growth and development and play...
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Putting the “mi” in omics: discovering miRNA biomarkers for pediatric precision care
AbstractIn the past decade, growing interest in micro-ribonucleic acids (miRNAs) has catapulted these small, non-coding nucleic acids to the...
