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MiR-449b-5p targets lncRNA PSMG3-AS1 to suppress cancer cell proliferation in lung adenocarcinoma
BackgroundPSMG3-AS1 has been characterized as an oncogenic lncRNA in breast cancer, while its role in other cancers is unknown. This study...
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A summary of our serial study: mechanism of invasion and metastasis in nasopharyngeal carcinoma
PurposeThe patients who have nasopharyngeal carcinoma (NPC) have high possibility to metastases. Therefore, it is of great practical significance to...
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MicroRNAs as the critical regulators of Forkhead box protein family during gynecological and breast tumor progression and metastasis
Gynecological and breast tumors are one of the main causes of cancer-related mortalities among women. Despite recent advances in diagnostic and...
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LncRNA CASC19: a novel oncogene involved in human cancer
Multiple studies have shown that long non-coding RNAs (lncRNAs) play an important role in the occurrence and development of diverse cancers. Cancer...
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Small RNAs, spermatogenesis, and male infertility: a decade of retrospect
Small non-coding RNAs (sncRNAs), being the top regulators of gene expression, have been thoroughly studied in various biological systems, including...
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Liquid biopsy using non-coding RNAs and extracellular vesicles for breast cancer management
This article examines liquid biopsy using non-coding RNAs and extracellular vesicles in detail. Liquid biopsy is emerging as a prominent non-invasive...
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Dynamic Role of miRNAs in Salivary Gland Carcinomas: From Biomarkers to Therapeutic Targets
BackgroundSalivary gland carcinomas (SGCs) are a rare group of malignant neoplasms of the head and neck region. MicroRNAs (miRNAs) are a class of...
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MicroRNA Signature and Cellular Characterization of Undifferentiated and Differentiated House Ear Institute-Organ of Corti 1 (HEI-OC1) Cells
MicroRNAs (miRNAs) regulate gene expressions and control a wide variety of cellular functions. House Ear Institute-Organ of Corti 1 (HEI-OC1) cells...
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miR-603 promotes cell proliferation and differentiation by targeting TrkB in acute promyelocytic leukemia
Arsenic trioxide (ATO) treatment effectively prolongs the overall survival of patients with acute promyelocytic leukemia (APL). Mutations in the...
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Role of repressed microRNAs in endometriosis
Endometriosis is a common, estrogen-dependent benign tumor that affect 3–10% women of reproductive age, and is characterized by the ectopic growth of...
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The crosstalk between long non-coding RNAs and the hedgehog signaling pathway in cancer
Hedgehog (Hh) is a conserved signaling pathway that is involved in embryo development as well as adult tissue maintenance and repair in invertebrates...
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Exploring the enigma: history, present, and future of long non-coding RNAs in cancer
Long noncoding RNAs (lncRNAs), which are more than 200 nucleotides in length and do not encode proteins, play crucial roles in governing gene...
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Recent miRNA Research in Asthma
Purpose of ReviewThe study of microRNA in asthma has revealed a vibrant new level of gene regulation underlying asthma pathology. Several miRNAs have...
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Deciphering glioma epitranscriptome: focus on RNA modifications
Gliomas are highly malignant tumors accounting for the majority of brain neoplasms. They are characterized by nuclear atypia, high mitotic rate and...
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miRNA Profiling of Major Testicular Germ Cells Identifies Stage-Specific Regulators of Spermatogenesis
Spermatogenesis is tightly controlled at transcriptional, post-transcriptional, and epigenetic levels by various regulators, including miRNAs. This...
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Decoding the regulatory landscape of lncRNAs as potential diagnostic and prognostic biomarkers for gastric and colorectal cancers
Colorectal cancer (CRC) and gastric cancer (GC) are major contributors to cancer-related mortality worldwide. Despite advancements in understanding...
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A comprehensive survey into the role of microRNAs in ovarian cancer chemoresistance; an updated overview
Ovarian cancer (OC), a frequent malignant tumor that affects women, is one of the leading causes of cancer-related death in this group of...
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Long non-coding RNAs in brain tumors: roles and potential as therapeutic targets
Brain tumors are associated with adverse outcomes despite improvements in radiation therapy, chemotherapy, and photodynamic therapy. However,...
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LncRNA–miRNA–mRNA regulatory axes in endometrial cancer: a comprehensive overview
IntroductionRecent research on tumorigenesis and progression has opened up an array of novel molecular mechanisms in the form of interactions between...
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Why Is It So Difficult To Have Competent Oocytes from In vitro Cultured Preantral Follicles?
The developmental competence of oocytes is acquired gradually during follicular development, mainly through oocyte accumulation of RNA molecules and...
